A comparative analysis of cerebral asymmetry according to data from perfusion computed tomography in infarctions of the cerebral hemispheres and dyscirculatory encephalopathy

2015 ◽  
Vol 9 (4) ◽  
pp. 0-0
Author(s):  
Сеинова ◽  
L. Seinova

Currently a problem of timely diagnostics and treatment of disorders of cerebral circulation is one of the most important for medicine, as strokes and chronic brain ischemia occupy a significant place among the diseases leading to mortality and disability of population. Computed tomography is one of the leading diagnostics of cerebro-vascular disorders. Today, the diagnostic capabilities of perfusion computed tomography, especially in the field of subtle changes in perfusion in infected and in the contralateral hemispheres of the brain are poorly understood and aren’t used in full. The relevance and scientific novelty of this research is not in doubt. Based on the data of 87 patients with ischemic infarction of the cerebral hemispheres of the brain and vascular encephalopathy, a comparative analysis of blood flow in the affected and contralateral hemispheres, was carried out. The degree of asymmetry of blood flow depending on the phase of development of ischemic stroke and chronic brain ischemia was evaluated. The studies have shown that the relative indicator of inter-hemispheric asymmetry is reduced in the course of development of cerebral infarction, reaching minimum values of dyscirculatory encephalopathy. The author substantiates the practical use of the proposed indicator of inter-hemispheric asymmetry in the evaluation of the degree of chronic ischemic disturbances of cerebral blood flow.

Author(s):  
N. K. Svyrydovа ◽  
G. S. Lubenets

The incidence of hypertension is an independent risk factor for cerebrovascular disease. A special problem is uncontrolled hypertension, with the progression of which is 7 times more likely to develop chronic ischemia. At the present stage of diagnosis and treatment of uncontrolled hypertension hypertensive crises is the problem as critical state. Violation of cerebral hemodynamics and function of the brain in patients with chronic brain ischemia determine the clinical picture of hypertensive crisis complicated course. The article highlights the theoretical foundations of the mechanisms of etiopathogenetical, clinical course, diagnosis and modern aspects of the treatment of chronic brain ischemia in the development of hypertensive crisis. The results of their research on the changes of regional cerebral blood flow, cerebral blood flow parameters or transient change in the substance of the brain after hypertensive crises using modern research methods: daily monitoring of blood pressure and single photon emission computed tomography.


2020 ◽  
Vol 101 (1) ◽  
pp. 124-131
Author(s):  
K G Valeeva ◽  
S K Perminova ◽  
A Ya Nazipova ◽  
S V Kurochkin ◽  
A A Yakupova

Aim. Assessment of cerebral blood flow in various vascular beds in patients with an acute cerebrovascular accident in the acute period by perfusion computed tomography in combination with transcranial Doppler ultrasonography of cerebral vessels. Methods. Data was analyzed from perfusion computed tomography of the brain and transcranial Doppler ultrasonography in 35 patients with an acute cerebrovascular accident, based at the vascular centre of the City Clinical Hospital No. 7 of Kazan. The study included 18 (51.4%) women and 17 (48.6%) men who had arrived in the first hours after a vascular accident. When analyzing the stroke subtype, atherothrombotic subtype was determined in 27 (77.1%) patients, cardioembolic subtype in 5 (14.3%) patients, and 3 (8.6%) patients had had a transient ischemic attack. Results. Perfusion computed tomography is a method that allowed evaluation of the structure of the brain, and blood supply to the anterior cerebral (in 2.9% of the studied patients), middle cerebral (in 62.9% of the studied patients), posterior cerebral (in 11.4% of the studied patients) and vertebral (in 14.2% of the studied patients) arteries of patients with a stroke. The method revealed a zone of critical perfusion (ischemic penumbra) by quantitatively processing perfusion indicators in the anterior cerebral blood flow system (decrease in rate and increase in average volume of cerebral blood flow and average transit time) and in the posterior cerebral circulation system (decrease in blood flow and prolongation of transit time) in the bed of the right vertebral artery). The method also aided the construction of perfusion maps. Transcranial Doppler ultrasonography of cerebral vessels revealed breaches in the cerebral circulation: a decrease in the linear velocity of blood flow in the right middle cerebral arterial bed and in the posterior circulatory system of blood flow in the brain, and an increase in the pulsatility index in all the studied vascular beds. Conclusion. Perfusion computed tomography of the brain in combination with transcranial Doppler ultrasonography is applicable to patients with stroke in various vascular beds, followed by determination of indications for thrombolytic therapy and thrombectomy.


2008 ◽  
Vol 70 (9) ◽  
pp. 981-983 ◽  
Author(s):  
Miori KISHIMOTO ◽  
Kazutaka YAMADA ◽  
Joon-Soo SEOK ◽  
Junichiro SHIMIZU ◽  
Yoshiyasu KOBAYASHI ◽  
...  

2019 ◽  
Author(s):  
Kiyohiko Shuto ◽  
Mikito Mori ◽  
Chihiro Kosugi ◽  
Kazuo Narushima ◽  
Satoko Nakabayashi ◽  
...  

Author(s):  
T.V. Cherniy ◽  
D.A. Fokina ◽  
V.I. Cherniy

Background. Vascular cerebral pathology, caused by a slowly progressing diffuse insufficiency of blood supply to brain tissue, leads to a progressive impairment of brain function, is a predictor of stroke, shaping the development of immune failure of brain tissue. Perspective direction of protection of the brain from chronic ischemia – direct influence on the systems of neurotransmitters and neuromodulators of the brain, normalization of the ratio of the processes of excitatory and inhibitory neurotransmission, individual approach to the restoration of impaired functions, activation of additional reserves of the brain, based on different treatments. Aim: to develop a method of complex treatment of patients with chronic brain ischemia (CВI), stroke, which includes targeted correction of cognitive impairment and restoration of motor functions. Material and methods. In the period from 2016 to 2019, a total of 118 people aged 51 to 78 years with chronic cerebral ischemia without concomitant hypertension, with a history of hypertension, with CBI and a stroke with a history without movement disorders, and with disorders of arbitrary disorders were comprehensively examined, with the formation of persistent neurological deficit. Among the examined patients were 40 men and 78 women. The diagnosis was confirmed by the data of general clinical, neurological, laboratory, instrumental examination, neuropsychological testing (MMSE, DASS-21). In addition to the protocol, patients with CBI received a complex of drugs aimed at the correction of neurotransmitter metabolism: ipidacrine hydrochloride monohydrate, choline alphoscerate, citicolin for 14 days. In patients with impaired arbitrary movements additionally used the hardware-software complex «Trenar-01» in the program «Donor». Results. Supplementation of the protocol of treatment of patients with CBI in all study groups with a complex of drugs aimed at eliminating cholinergic insufficiency led to the correction of cognitive disorders in chronic brain ischemia. The use of the hardware-software complex «Trenar-01» in the course of treatment repeatedly increases the strength and function of stimulated muscles, which allows normalizing static and motor disorders faster. Conclusion. The complex of drugs aimed at eliminating cholinergic insufficiency, the use of the apparatus for electrical stimulation with biocontrol «Trenar-01» leads to the correction of cognitive impairment and the restoration of arbitrary movements in patients with CBI who have suffered a stroke with motor disorders.


2021 ◽  
Author(s):  
Karine Felipe Martins ◽  
Flávia Pascoal Teles ◽  
Amanda Fernandes de Sousa Oliveira Balestra ◽  
Isadora Rosa Maia

Background: Until the 70s, cerebrovascular diseases (CVDs) were neglected to the lack of resources. However, due to the advancement of technology, several imaging tests have appeared, such as magnetic resonance and computed tomography, which facilitated the diagnosis and the understanding of the pathophysiology of each disease. Objectives: The objective of this work is to identify the main CVDs signs and symptoms. Methods: An integrative literature review was carried out based on selected articles from Google Scholar, PubMed and SciELO, using the terms headache, cerebrovascular disease, neurology. Results: CVDs are characterized by causing damage to brain vessels, due to changes in blood flow momentarily or permanently in an area of the brain, allowing them to be classified as ischemic or hemorrhagic. In ischemic there is a blockage of blood flow and, consequently, of oxygen to areas of the brain, in hemorrhagic rupture of a vessel occurs and, with this, blood leakage. Therefore, it is necessary to recognize the signs and symptoms early, in order to prevent loss of neurological function, movements on one side of the body and the presence or absence of headaches in both patients, with ischemic CVD and hemorrhagic CVD prevent rapid loss of consciousness accompanied by severe headache. Such signs and symptoms associated with the patient’s family history and lifestyle can help in the diagnosis of this disease. Conclusion: Therefore, it is important to recognize the signs and symptoms of CVDs, in order to determine the treatment and advise the patient, which will guarantee a better prognosis.


2012 ◽  
Vol 10 (2) ◽  
pp. 8-13
Author(s):  
Ludmila Konstantinovna Khnychenko

The review represents recent data devoted to pathogenesis of the brain ischemia and pharmacological ways to correct metabolic shifts in the cerebral blood flow disorders.


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