scholarly journals Changes in Activities of Enzymes Related to Energy Metabolism in Canine Lymphoma Cells

2005 ◽  
Vol 67 (6) ◽  
pp. 615-616 ◽  
Author(s):  
Tsukimi WASHIZU ◽  
Daigo AZAKAMI ◽  
Makoto BONKOBARA ◽  
Makoto WASHIZU ◽  
Toshiro ARAI
Keyword(s):  
Energy Metabolism ◽  
Lymphoma Cells ◽  
Canine Lymphoma

scholarly journals Silver sulfide nanoparticles for photodynamic therapy of human lymphoma cells via disruption of energy metabolism

RSC Advances ◽  
2019 ◽  
Vol 9 (51) ◽  
pp. 29936-29941 ◽  
Author(s):  
Ge Wang ◽  
Jing Liu ◽  
Lin Zhu ◽  
Yuming Guo ◽  
Lin Yang
Keyword(s):  
Photodynamic Therapy ◽  
Energy Metabolism ◽  
Silver Sulfide ◽  
Light Irradiation ◽  
Hybrid Nanoparticles ◽  
Reactive Oxidative Species ◽  
Lymphoma Cells ◽  
Human Lymphoma ◽  
Silver Sulfide Nanoparticles ◽  
Oxidative Species

Ag2S/BSA hybrid nanoparticles were prepared and studied for their ability to inhibit the growth of human lymphoma cells under light irradiation, via inducing the accumulation of intracellular reactive oxidative species to disrupt energy metabolism.

scholarly journals Evaluation of a side population of canine lymphoma cells using Hoechst 33342 dye

2013 ◽  
Vol 14 (4) ◽  
pp. 481 ◽  
Author(s):  
Myung-Chul Kim ◽  
Susan D'Costa ◽  
Steven Suter ◽  
Yongbaek Kim
Keyword(s):  
Side Population ◽  
Lymphoma Cells ◽  
Hoechst 33342 ◽  
Canine Lymphoma

scholarly journals In vitro antineoplastic effects of auranofin in canine lymphoma cells

BMC Cancer ◽  
2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Hong Zhang ◽  
Barbara J. Rose ◽  
Alex A. Pyuen ◽  
Douglas H. Thamm
Keyword(s):  
Lymphoma Cells ◽  
Canine Lymphoma

scholarly journals Pharmacological targeting of valosin containing protein (VCP) induces DNA damage and selectively kills canine lymphoma cells

BMC Cancer ◽  
2015 ◽  
Vol 15 (1) ◽  
Author(s):  
Marie-Ève Nadeau ◽  
Charlène Rico ◽  
Mayra Tsoi ◽  
Mélanie Vivancos ◽  
Sabin Filimon ◽  
...  
Keyword(s):  
Dna Damage ◽  
Lymphoma Cells ◽  
Canine Lymphoma

scholarly journals Characterization of the novel indolylmaleimides' PDA-66 and PDA-377 effect on canine lymphoma cells

Oncotarget ◽  
2016 ◽  
Vol 7 (23) ◽  
pp. 35379-35389 ◽  
Author(s):  
Wen Liu ◽  
Julia Beck ◽  
Laura C. Schmidt ◽  
Catrin Roolf ◽  
Anahit Pews-Davtyan ◽  
...  
Keyword(s):  
The Novel ◽  
Lymphoma Cells ◽  
Canine Lymphoma

scholarly journals Hypoxia-activated prodrug TH-302 decreased survival rate of canine lymphoma cells under hypoxic condition

PLoS ONE ◽  
2017 ◽  
Vol 12 (5) ◽  
pp. e0177305
Author(s):  
Hiroki Yamazaki ◽  
Yu-Chang Lai ◽  
Morihiro Tateno ◽  
Asuka Setoguchi ◽  
Yuko Goto-Koshino ◽  
...  
Keyword(s):  
Survival Rate ◽  
Hypoxic Condition ◽  
Lymphoma Cells ◽  
Canine Lymphoma

scholarly journals In vitro drug sensitivity in canine lymphoma

2016 ◽  
Vol 60 (1) ◽  
pp. 55-61 ◽  
Author(s):  
Aleksandra Pawlak ◽  
Bożena Obmińska-Mrukowicz ◽  
Iwona Zbyryt ◽  
Andrzej Rapak
Keyword(s):  
Cell Viability ◽  
Annexin V ◽  
In Vitro Assays ◽  
In Vitro Tests ◽  
Primary Lymphoma ◽  
High Grade ◽  
Lymphoma Cells ◽  
Canine Lymphoma ◽  
Induced Apoptosis

AbstractIntroduction: Due to the high heterogeneity of canine lymphoma, the aim of the present study was to test in vitro the chemosensitivity of canine high-grade primary lymphoma cells to various cytostatic drugs commonly used to treat dogs: 4-HO-cyclophosphamide, doxorubicin, dexamethasone, prednisolone, vincristine, etoposide, chlorambucil, lomustine, and cytosine arabinoside. Material and Methods: To determine the cell viability and drug ability to induce apoptosis two different tests were used: an MTT assay and annexin V/propidium iodide staining. Results: Both in vitro tests were found to be useful tools. Significant differences in the sensitivity, depending on the drug type, between B-, T- and mixed/null-type lymphoma cells were found for the majority of the tested drugs. B-type cells were the most sensitive in vitro, whereas T-type cells seemed to be the most resistant. Doxorubicin, chlorambucil, etoposide, and vincristine most strongly reduced the cell viability and induced apoptosis. Conclusion: In vitro assays, such as the MTT test and especially the annexin V/PI assay, may be useful tools for predicting a response to the treatment of high-grade lymphoma in dogs or improving the treatment outcomes in individual animals.

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