scholarly journals Identification of Effective Component from a Traditional Herbal Medicine and the Inhibitory Effects on Experimental Glomerular Lesion in Mice.

1992 ◽  
Vol 54 (1) ◽  
pp. 111-118 ◽  
Author(s):  
Koji SUGIMOTO ◽  
Nobuo SAKURAI ◽  
Yutaka FUJISE ◽  
Haruyuki SHIRASAWA ◽  
Kiyoshi SHIBATA ◽  
...  
Keyword(s):  
Herbal Medicine ◽  
Inhibitory Effects ◽  
Traditional Herbal Medicine ◽  
Glomerular Lesion ◽  
Effective Component

scholarly journals Two Novel Quassinoid Glycosides with Antiviral Activity from the Samara of Ailanthus altissima

Molecules ◽  
2020 ◽  
Vol 25 (23) ◽  
pp. 5679
Author(s):  
Qing-Wei Tan ◽  
Jian-Cheng Ni ◽  
Jian-Ting Shi ◽  
Jian-Xuan Zhu ◽  
Qi-Jian Chen
Keyword(s):  
Data Analysis ◽  
Herbal Medicine ◽  
Inhibitory Concentration ◽  
Biological Activities ◽  
Virus Multiplication ◽  
Ailanthus Altissima ◽  
Inhibitory Effects ◽  
Traditional Herbal Medicine ◽  
Virus Activity ◽  
Ic50 Values

Phytochemistry investigations on Ailanthus altissima (Mill.) Swingle, a Simaroubaceae plant that is recognized as a traditional herbal medicine, have afforded various natural products, among which C20 quassinoid is the most attractive for their significant and diverse pharmacological and biological activities. Our continuous study has led to the isolation of two novel quassinoid glycosides, named chuglycosides J and K, together with fourteen known lignans from the samara of A. altissima. The new structures were elucidated based on comprehensive spectra data analysis. All of the compounds were evaluated for their anti-tobacco mosaic virus activity, among which chuglycosides J and K exhibited inhibitory effects against the virus multiplication with half maximal inhibitory concentration (IC50) values of 56.21 ± 1.86 and 137.74 ± 3.57 μM, respectively.

scholarly journals A pathologic study on the inhibitory effects of a herbal medicine against the glomerular lesion induced by Agkistrodon venom in mice.

1991 ◽  
Vol 53 (2) ◽  
pp. 255-262
Author(s):  
Koji SUGIMOTO ◽  
Nobuo SAKURAI ◽  
Haruyuki SHIRASAWA ◽  
Masao KANEKO ◽  
Yutaka FUJISE ◽  
...  
Keyword(s):  
Herbal Medicine ◽  
Inhibitory Effects ◽  
Glomerular Lesion ◽  
Pathologic Study
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