scholarly journals A pathologic study on the inhibitory effects of a herbal medicine against the glomerular lesion induced by Agkistrodon venom in mice.

1991 ◽  
Vol 53 (2) ◽  
pp. 255-262
Author(s):  
Koji SUGIMOTO ◽  
Nobuo SAKURAI ◽  
Haruyuki SHIRASAWA ◽  
Masao KANEKO ◽  
Yutaka FUJISE ◽  
...  
1992 ◽  
Vol 54 (1) ◽  
pp. 111-118 ◽  
Author(s):  
Koji SUGIMOTO ◽  
Nobuo SAKURAI ◽  
Yutaka FUJISE ◽  
Haruyuki SHIRASAWA ◽  
Kiyoshi SHIBATA ◽  
...  

Molecules ◽  
2020 ◽  
Vol 25 (23) ◽  
pp. 5679
Author(s):  
Qing-Wei Tan ◽  
Jian-Cheng Ni ◽  
Jian-Ting Shi ◽  
Jian-Xuan Zhu ◽  
Qi-Jian Chen

Phytochemistry investigations on Ailanthus altissima (Mill.) Swingle, a Simaroubaceae plant that is recognized as a traditional herbal medicine, have afforded various natural products, among which C20 quassinoid is the most attractive for their significant and diverse pharmacological and biological activities. Our continuous study has led to the isolation of two novel quassinoid glycosides, named chuglycosides J and K, together with fourteen known lignans from the samara of A. altissima. The new structures were elucidated based on comprehensive spectra data analysis. All of the compounds were evaluated for their anti-tobacco mosaic virus activity, among which chuglycosides J and K exhibited inhibitory effects against the virus multiplication with half maximal inhibitory concentration (IC50) values of 56.21 ± 1.86 and 137.74 ± 3.57 μM, respectively.


1994 ◽  
Vol 22 (02) ◽  
pp. 191-196 ◽  
Author(s):  
Katsuhisa Ikeda ◽  
Da-Zheng Wu ◽  
Motoaki Ishigaki ◽  
Hiroshi Sunose ◽  
Tomonori Takasaka

Sho-seiryu-to, a traditional Japanese herbal medicine, has been used extensively in the treatment of allergic rhinitis. The effects of Sho-seiryu-to on electrical responses induced by acetylcholine in dissociated nasal gland acinar cells were investigated using patch-clamp and microfluorimetric imaging techniques. The application of Sho-seiryu-to inhibited both K+ and Cl- currents augmented by acetylcholine. The elevation of intracellular Ca2+ and Na+ concentrations induced by acetylcholine was also inhibited by Sho-seiryu-to. These findings suggest that Sho-seiryu-to attenuated the secretion of water and electrolytes from the nasal glands through an anti-cholinergic effect.


2012 ◽  
Vol 60 (3) ◽  
pp. 363-370 ◽  
Author(s):  
Mohamed-Elamir F. Hegazy ◽  
Hisashi Matsuda ◽  
Seikou Nakamura ◽  
Mikuko Yabe ◽  
Tomoko Matsumoto ◽  
...  

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