scholarly journals C-Reactive Protein, Left Ventricular Mass Index, and Risk of Cardiovascular Disease in Essential Hypertension

2007 ◽  
Vol 30 (12) ◽  
pp. 1177-1185 ◽  
Author(s):  
Yoshio IWASHIMA ◽  
Takeshi HORIO ◽  
Kei KAMIDE ◽  
Hiromi RAKUGI ◽  
Toshio OGIHARA ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Essential Hypertension ◽  
Left Ventricular Mass ◽  
Left Ventricular Mass Index ◽  
Left Ventricular ◽  
C Reactive Protein ◽  
Ventricular Mass Index ◽  
Reactive Protein ◽  
Ventricular Mass

scholarly journals Uric Acid, Left Ventricular Mass Index, and Risk of Cardiovascular Disease in Essential Hypertension

Hypertension ◽  
2006 ◽  
Vol 47 (2) ◽  
pp. 195-202 ◽  
Author(s):  
Yoshio Iwashima ◽  
Takeshi Horio ◽  
Kei Kamide ◽  
Hiromi Rakugi ◽  
Toshio Ogihara ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Uric Acid ◽  
Essential Hypertension ◽  
Left Ventricular Mass ◽  
Left Ventricular Mass Index ◽  
Left Ventricular ◽  
Ventricular Mass Index ◽  
Ventricular Mass

scholarly journals C-reactive Protein is an Independent Predictor of Left Ventricular Mass in Offspring of Hypertensive Subjects in Nigeria

2020 ◽  
pp. 11-21
Author(s):  
O. M. Akinlade ◽  
A. A. Akintunde ◽  
F. T. Akinlade ◽  
O. A. Adeyemi ◽  
J. O. Akande ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Left Ventricular Mass ◽  
Left Ventricular Mass Index ◽  
Left Ventricular ◽  
Systemic Hypertension ◽  
C Reactive Protein ◽  
Ventricular Mass Index ◽  
Reactive Protein ◽  
Ventricular Mass ◽  
Increased Risk

Offspring of hypertensive parents have been shown to be at increased risk of developing systemic hypertension and adverse cardiovascular events later in life. The pathological antecedents of this are thought to be alterations in the structure and function of left ventricle. However, it is currently unclear if these abnormalities are due to genetic factors or a result of higher biomarker levels such as highly sensitive C reactive protein (hsCRP). An improved understanding of the associations of hsCRP with left ventricular structure may offer additional insight. Therefore, this study aims at determining the correlation of left ventricular mass with hsCRP among offspring of hypertensive parents compared with controls. Methodology: A cross sectional Hospital based study, with 100 subjects and 100 controls. A questionnaire was administered to obtain relevant history, physical examination, blood tests, ECG, Echocardiography were done for the two groups. The results were analysed using SPSS 20.  Results: The left ventricular mass and mass index was significantly elevated in the subjects compared with the control group. The median hsCRP was significantly higher in the subjects [1.85 (0.28-10.20) vs. 1.34 (0.17-8.49) mg/L: P < 0.010]. It progressively increases significantly as the number of parent with hypertension increases [1.34 (0.17-8.49), 2.00(0.28-9.66) and 2.54(0.91-10.20) mg/L P < 0.001] from zero, to single and both parent respectively. There was a significant correlation between hsCRP levels, blood pressure, left ventricular mass and left ventricular mass index (R = 0.165, 0.316, 0.274: P = 0.021, 0.004, 0.014) respectively. Conclusion: The study shows that offspring of hypertensive parents had higher echocardiographic left ventricular mass, left ventricular mass index and hsCRP levels compared with controls and this hsCRP increases as the number of parents with hypertension increases. Blood pressure and left ventricular mass index increase with increasing Plasma hsCRP: This may suggest possible role of hsCRP in the development of hypertension and cardiac remodeling.

scholarly journals Long-term effect of efonidipine therapy on plasma aldosterone and left ventricular mass index in patients with essential hypertension

2009 ◽  
Vol 32 (8) ◽  
pp. 670-674 ◽  
Author(s):  
Takayoshi Tsutamoto ◽  
Toshinari Tanaka ◽  
Keizo Nishiyama ◽  
Masayuki Yamaji ◽  
Chiho Kawahara ◽  
...  
Keyword(s):  
Essential Hypertension ◽  
Left Ventricular Mass ◽  
Left Ventricular Mass Index ◽  
Left Ventricular ◽  
Plasma Aldosterone ◽  
Term Effect ◽  
Ventricular Mass Index ◽  
Ventricular Mass ◽  
Long Term Effect

scholarly journals Association Between AGT M235T and Left Ventricular Mass in Vietnamese Patients Diagnosed With Essential Hypertension

2021 ◽  
Vol 8 ◽  
Author(s):  
Tuan Thanh Tran ◽  
Thao Phuong Mai ◽  
Ha Chau Bich Tran ◽  
Linh Hoang Gia Le ◽  
Hoang Anh Vu ◽  
...  
Keyword(s):  
Essential Hypertension ◽  
Left Ventricular Mass ◽  
Left Ventricular Mass Index ◽  
Left Ventricular ◽  
Hypertensive Patients ◽  
Ventricular Mass Index ◽  
Independent Prognostic Marker ◽  
Asian Populations ◽  
Ventricular Mass ◽  
2D Echocardiography

Background: Increasing left ventricular mass in hypertensive patients is an independent prognostic marker for adverse cardiovascular outcomes. Genetic factors have been shown to critically affect left ventricular mass. AGT M235T is one of the genetic polymorphisms that may influence left ventricular mass due to its pivotal role in the regulation of plasma angiotensinogen level as well as hypertension pathophysiology in Asian populations. Currently, how M235T affects left ventricular mass is not well-described in Vietnamese hypertensive patients. This study aimed to investigate the association between M235T and left ventricular mass in Vietnamese patients diagnosed with essential hypertension.Materials and Methods:AGT M235T genotyping and 2D echocardiography were performed on 187 Vietnamese subjects with essential hypertension. All the ultrasound parameters were obtained to calculate the left ventricular mass index according to the American Society of Echocardiography and the European Association of Cardiovascular Imaging 2015 guidelines. Other clinical characteristics were also recorded, including age, gender, duration of hypertension, hypertensive treatment, lifestyle, renal function, fasting plasma glucose, and lipid profile.Results: MT and TT genotypes were determined in 30 and 157 subjects, respectively. AGT M235T genotype, duration of hypertension, body mass index, and ejection fraction statistically affected the left ventricular mass index, which was significantly greater in TT compared to MT carriers after adjusting for confounding factors.Conclusion: The TT genotype of AGT M23T was associated with greater left ventricular mass in Vietnamese patients diagnosed with essential hypertension.

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