DNA methylation profiles associated with persistent organic pollutants body burden in Greenlandic Inuit

2016 ◽  
Vol 2016 (1) ◽  
Author(s):  
Jennifer Rusiecki* ◽  
Lee Moore ◽  
Tiffany Oliver ◽  
Li Wang ◽  
Ligong Chen ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Organic Pollutants ◽  
Persistent Organic Pollutants ◽  
Body Burden

scholarly journals Maternal plasma concentrations of persistent organic pollutants and placental DNA methylation

2020 ◽  
Vol 2020 (1) ◽  
Author(s):  
M. Ouidir ◽  
P. Mendola ◽  
G.M. Buck Louis ◽  
K. Kannan ◽  
C. Zhang ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Organic Pollutants ◽  
Persistent Organic Pollutants ◽  
Plasma Concentrations ◽  
Maternal Plasma

Body burden of persistent organic pollutants on hypertension: a meta-analysis

2016 ◽  
Vol 23 (14) ◽  
pp. 14284-14293 ◽  
Author(s):  
Su Hyun Park ◽  
Jung-eun Lim ◽  
Hyesook Park ◽  
Sun Ha Jee
Keyword(s):  
Organic Pollutants ◽  
Persistent Organic Pollutants ◽  
Meta Analysis ◽  
Body Burden

DNA Methylation Among Greenlandic Inuit With Varying Levels of Exposures to Specific Persistent Organic Pollutants

Epidemiology ◽  
2007 ◽  
Vol 18 (Suppl) ◽  
pp. S151-S152 ◽  
Author(s):  
J Rusiecki ◽  
A Baccarelli ◽  
V Bollati ◽  
L Moore ◽  
E Bonefeld-Jorgensen
Keyword(s):  
Dna Methylation ◽  
Organic Pollutants ◽  
Persistent Organic Pollutants

scholarly journals Concentrations of persistent organic pollutants in maternal plasma and epigenome-wide placental DNA methylation

2020 ◽  
Vol 12 (1) ◽  
Author(s):  
Marion Ouidir ◽  
Pauline Mendola ◽  
Germaine M. Buck Louis ◽  
Kurunthachalam Kannan ◽  
Cuilin Zhang ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Organic Pollutants ◽  
Persistent Organic Pollutants ◽  
Maternal Plasma

scholarly journals Association between DNA methylation profiles in leukocytes and serum levels of persistent organic pollutants in Dutch men

2017 ◽  
Vol 3 (1) ◽  
Author(s):  
Myrthe W. van den Dungen ◽  
Albertinka J. Murk ◽  
Ellen Kampman ◽  
Wilma T. Steegenga ◽  
Dieuwertje E. Kok
Keyword(s):  
Dna Methylation ◽  
Organic Pollutants ◽  
Persistent Organic Pollutants ◽  
Serum Levels

scholarly journals Time Trend of Persistent Organic Pollutants and Metals in Greenlandic Inuit during 1994–2015

2021 ◽  
Vol 18 (5) ◽  
pp. 2774
Author(s):  
Manhai Long ◽  
Maria Wielsøe ◽  
Eva Cecilie Bonefeld-Jørgensen
Keyword(s):  
Organic Pollutants ◽  
Persistent Organic Pollutants ◽  
Marine Mammals ◽  
Body Burden ◽  
The Arctic ◽  
Marine Food Chain ◽  
Arctic Regions ◽  
Perfluorodecanoic Acid ◽  
Increasing Trend ◽  
Marine Food

Persistent organic pollutants (POPs), including polychlorinated biphenyls (PCBs), organchlorine pesticides and perfluoroalkylated substances (PFASs) and heavy metals bioaccumulate in the marine food chain in the Arctic regions, and thus, the Greenlandic population has a higher body burden due to relatively high intake of marine mammals. We assessed the temporal trend for POPs, including PCB 153; 1,1-dichloro−2,2-bis (p-chlorophenyl)-ethylene (p,p’-DDE); oxychlordane; six PFASs; mercury; lead and selenium in Inuit from Ilulissat, Nuuk, and across Greenland (including thirteen towns/districts), from 1994 to 2015. Data showed a significant annual decrease of 6.85–8.61% for PCB153, 6.67–8.61% for p,p’-DDE, 6.11–9.52% for oxychlordane, 5.92–6.76% for mercury and 6.48–9.43% for lead in Inuit women from Nuuk, Ilulissat, and across thirteen Greenlandic districts. The blood selenium level of all Greenlandic women increased 1.01% annually, while the trend direction was negative for Nuuk women. A similar pattern was seen for men across Greenland, with a yearly decrease of 11.3% for PCB 153, 8.61% for p,p’-DDE, 15.6% for oxychlordane, 13.1% for mercury and 12.2% for lead. Perfluorooctane sulfonate, perfluorohexane sulfonate and perfluorooctanoic acid significantly decreased 5.82–11.7% annually for both women and men across Greenland. For perfluorononanoic acid, perfluorodecanoic acid and perfluoroundecanoic acid, we observed an increasing trend for women across Greenland. In conclusion, there was a decreasing trend of the regulated POPs and metals but a potential increasing trend of the nonregulated PFASs in the Greenlandic population between 1994 and 2015. The continuing biomonitoring of contaminants of concern is important to protect the Arctic population heath.

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