LOW DOSE MIXTURE EFFECTS OF BISPHENOL A AND ISOBUTYLPARABEN FOR THE MALE REPRODUCTIVE SYSTEM

2011 ◽  
Vol 2011 (1) ◽  
Author(s):  
Yun-jung Yang ◽  
Mun-seo Park ◽  
Sang-yon Kim ◽  
Lee-so Maeng ◽  
Soon-chul Myoung ◽  
...  
Keyword(s):  
Bisphenol A ◽  
Reproductive System ◽  
Low Dose ◽  
Male Reproductive System ◽  
Mixture Effects

scholarly journals Bisphenol A-Induced Epigenetic Changes and Its Effects on the Male Reproductive System

2020 ◽  
Vol 11 ◽  
Author(s):  
Federica Cariati ◽  
Luigi Carbone ◽  
Alessandro Conforti ◽  
Francesca Bagnulo ◽  
Stefania Ramona Peluso ◽  
...  
Keyword(s):  
Bisphenol A ◽  
Reproductive System ◽  
Male Reproductive System ◽  
Epigenetic Changes

Prenatal bisphenol a and phthalate exposure are risk factors for male reproductive system development and cord blood sex hormone levels

2019 ◽  
Vol 87 ◽  
pp. 146-155 ◽  
Author(s):  
Birce Sunman ◽  
Kadriye Yurdakök ◽  
Belma Kocer-Gumusel ◽  
Özgür Özyüncü ◽  
Filiz Akbıyık ◽  
...  
Keyword(s):  
Risk Factors ◽  
Bisphenol A ◽  
Cord Blood ◽  
Reproductive System ◽  
System Development ◽  
Sex Hormone ◽  
Male Reproductive System ◽  
Hormone Levels ◽  
Phthalate Exposure

scholarly journals EFFECTS OF MATERNAL EXPOSURE TO A LOW DOSE OF DIETHYLSTILBESTROL ON SEXUAL DIMORPHIC NUCLEUS VOLUME AND MALE REPRODUCTIVE SYSTEM IN RAT OFFSPRING

2005 ◽  
Vol 30 (1) ◽  
pp. 7-18 ◽  
Author(s):  
Masako YAMAMOTO ◽  
Mitsuyuki SHIRAI ◽  
Aya TAMURA ◽  
Tetsuo KOBAYASHI ◽  
Shinnya KOHARA ◽  
...  
Keyword(s):  
Reproductive System ◽  
Low Dose ◽  
Maternal Exposure ◽  
Male Reproductive System ◽  
Rat Offspring ◽  
Nucleus Volume

scholarly journals Bisphenol-A Dose-dependently Regulates The Development of Ovary and Uterus through Differential Expression of METTL3

2020 ◽  
Author(s):  
Zhe Zhang ◽  
Yuan Zhu ◽  
Zhifan Zhang ◽  
Daojuan Wang ◽  
Hongwei Wang ◽  
...  
Keyword(s):  
Bisphenol A ◽  
Soybean Oil ◽  
Reproductive System ◽  
Low Dose ◽  
Polycystic Ovary ◽  
Female Rats ◽  
Control Group ◽  
Sprague Dawley ◽  
Blank Group ◽  
Rna Methylation

Abstract Background: Environmental endocrine disruptors, which have a profound impact on the reproductive system, can cause endocrine and reproductive disorders, such as polycystic ovary syndrome (PCOS). Bisphenol-A (BPA) is a common endocrine disruptor which can affect the function of the reproductive system under low-dose conditions. However, the mechanism by which this molecule disrupts normal reproduction is still unclear. In this study, we investigated the effects of BPA on the RNA methyltransferase METTL3 in adolescent female rats which may be a possible mode of action of BPA. Methods: 4-week-old Sprague-Dawley (SD) rats were intragastrically treated for 10 weeks, which were divided into blank group (n = 8), control group (soybean oil, n = 8), three BPA-treatment groups (0.5 mg/kg BPA + soybean oil, 5 mg/kg BPA + soybean oil, 50 mg/kg BPA + soybean oil, n = 8). Results: The results showed that low-dose BPA (0.5 mg/kg) increased the coefficient of uteri and ovaries, and promoted the growth of uteri in rats without causing hyperandrogenism and ovarian polycystic changes. Oral BPA disturbed the expression of CYP17A1, CYP11A1 and METTL3 in ovaries and effected the level of serum testosterone. Conclusions: Our results suggested that oral BPA might interfere uterine and ovarian morphology and the level of hormone with RNA methylation by disturbing the expression level of METTL3. RNA methylation will be a new way to explain the interference mechanism of BPA.

scholarly journals Evaluation of subacute bisphenol – A toxicity on male reproductive system

2015 ◽  
Vol 8 (6) ◽  
pp. 738-744 ◽  
Author(s):  
S. S. Karnam ◽  
R. C. Ghosh ◽  
S. Mondal ◽  
M. Mondal
Keyword(s):  
Bisphenol A ◽  
Reproductive System ◽  
Male Reproductive System
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