VERY HIGH CORRELATIONS BETWEEN FRESH WEIGHT AND LIPID-ADJUSTED PCB-153 SERUM CONCENTRATIONS – IRRESPECTIVE OF FASTING STATUS, AGE, BODY MASS INDEX, GENDER, OR EXPOSURE DISTRIBUTIONS

2011 ◽  
Vol 2011 (1) ◽  
Author(s):  
Lars Rylander ◽  
Anna Axmon ◽  
Aleksander Giwercman ◽  
Bo AG Jönsson ◽  
Christian Lindh ◽  
...  
Chemosphere ◽  
2012 ◽  
Vol 88 (7) ◽  
pp. 828-831 ◽  
Author(s):  
Lars Rylander ◽  
Carl-Magnus Björkdahl ◽  
Anna Axmon ◽  
Aleksander Giwercman ◽  
Bo A.G. Jönsson ◽  
...  

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Bodo Warrings ◽  
Lydia Samanski ◽  
Jürgen Deckert ◽  
Stefan Unterecker ◽  
Maike Scherf-Clavel

2008 ◽  
Vol 28 (2) ◽  
pp. 97-106 ◽  
Author(s):  
Judy D. Ribaya-Mercado ◽  
Cherry C. Maramag ◽  
Lorena W. Tengco ◽  
Jeffrey B. Blumberg ◽  
Florentino S. Solon

In marginally nourished children, information is scarce regarding the circulating concentrations of carotenoids and tocopherols, and physiological factors influencing their circulating levels. We determined the serum concentrations of carotenoids, tocopherols and retinol at steady state and in response to a 9-week vegetable diet intervention in 9–12-year-old girls (n=54) and boys (n=65) in rural Philippines. We determined cross-sectional relationships of BMI (body mass index) with serum micronutrient levels, and whether BMI is a determinant of serum carotenoid responses to the ingestion of carotenoid-rich vegetables. We measured dietary nutrient intakes and assessed inflammation by measurement of serum C-reactive protein levels. The children had low serum concentrations of carotenoids, tocopherols and retinol as compared with published values for similar-aged children in the U.S.A. The low serum retinol levels can be ascribed to inadequate diets and were not the result of confounding due to inflammation. Significant inverse correlations of BMI and serum all-trans-β-carotene, 13-cis-β-carotene, α-carotene, lutein, zeaxanthin and α-tocopherol (but not β-cryptoxanthin, lycopene and retinol) were observed among girls at baseline. The dietary intervention markedly enhanced the serum concentrations of all carotenoids. Changes in serum all-trans-β-carotene and α-carotene (but not changes in lutein, zeaxanthin and β-cryptoxanthin) in response to the dietary intervention were inversely associated with BMI in girls and boys. Thus, in Filipino school-aged children, BMI is inversely related to the steady-state serum concentrations of certain carotenoids and vitamin E, but not vitamin A, and is a determinant of serum β- and α-carotene responses, but not xanthophyll responses, to the ingestion of carotenoid-rich vegetable meals.


Author(s):  
Elsa Vitale ◽  
Rocco Mea ◽  
Francesca Di Dio ◽  
Anna Canonico ◽  
Vito Galatola

Background: A new Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2) (COVID-19) infection was reported in Wuhan, China, and quickly spread, becoming a global health emergency. Literature shows how nursing work is particularly stressful and how this condition is closely connected to the development of anxiety disorders, sleep quality and can also influence eating behavior with consequent variations in BMI values. Objective: The study aims to investigate and correlate the levels of anxiety, insomnia and Body Mass Index among nurses directly involved in the care of patients in the intensive care units with the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2) infection. Method: An observatory study was conducted assessing and correlating the anxiety and insomnia levels and BMI values of each nurse before (until December 2019) and during (until May 2020) the pandemic. Results: In total, 291 Italian nurses joined the study. There are no statistically significant differences between female nurses and male nurses for both groups of participants with or without anxiety (p=0.655). Female nurses with mild, moderate and severe insomnia levels were statistically more numerous than male nurses (p=0.025). For the same BMI differences, the levels of anxiety and insomnia were statistically significant between them (p<0.001). Conclusion: Nurses engaged in the treatment of the most serious patients with Covid-19 are subjected to very high levels of stress due to the nature of the nursing job, shifting, poor rest, anxiety due to health emergency period and weight gain.


Author(s):  
Juliette Raffort ◽  
Patricia Panaïa-Ferrari ◽  
Fabien Lareyre ◽  
Mathilde Blois ◽  
Pascale Bayer ◽  
...  

Background Proglucagon-derived hormones represent a family of peptides mainly produced in the pancreas and the intestine. While several proglucagon-derived peptides play key roles in metabolic diseases, little is known about glicentin. The aim of the present study was to investigate serum glicentin concentrations in individuals with adult obesity and to study its potential link with various metabolic parameters. Methods Fifty-two individuals with normal body mass index (BMI < 25 kg/m2) and 39 patients with severe or morbid obesity (BMI > 35 kg/m2) were prospectively included at the University Hospital of Nice between January 2014 and April 2016. Clinical data were recorded, and a fasting blood sample was collected to measure glicentin, glucose, insulin, C-peptide, total cholesterol, triglyceride, LDL and HDL-cholesterol. In addition, a homeostasis model assessment for insulin resistance (HOMA2-IR) was also calculated. Results Patients with severe and morbid obesity had significantly higher plasma glucose, together with higher serum concentrations of insulin, C-peptide, HOMA2-IR, triglyceride, LDL-cholesterol and lower serum concentrations of HDL-cholesterol compared with individuals with a normal body mass index. The obese patients displayed significantly lower fasting serum concentrations of glicentin compared with subjects with a normal body mass index (12 pmol/L vs. 24 pmol/L, P < 0.0001). In the total population, fasting glicentin concentrations did not correlate with BMI, glycaemic parameters (glucose, insulin, C-peptide, HOMA-IR) or lipid parameters (total cholesterol, triglyceride, LDL and HDL-cholesterol). Conclusion To the best of our knowledge, this is the first study reporting serum glicentin concentrations in healthy lean and obese adult subjects. We found that fasting serum glicentin concentrations are decreased in patients with severe or morbid obesity suggesting the potential interest of this peptide in obesity and metabolic-related disorders.


2015 ◽  
pp. 701-709 ◽  
Author(s):  
J. OŚWIĘCIMSKA ◽  
A. SUWAŁA ◽  
E. ŚWIĘTOCHOWSKA ◽  
Z. OSTROWSKA ◽  
P. GORCZYCA ◽  
...  

It is believed that omentin is secreted by stromal cells of adipose tissue and modulates insulin sensitivity. Data from a few studies have shown lower serum omentin in obese children and higher in anorexia nervosa. However, to date, there is lack of research on serum omentin concentrations in adolescent patients in a wide range of body mass index (BMI) and insulin resistance. In this cross-sectional study omentin-1 serum concentrations were evaluated using commercially available ELISA kit in 47 Polish girls with restrictive anorexia nervosa (AN), 50 with simple obesity (OB) and 39 healthy controls (C). The mean serum omentin-1 concentration in girls with AN was statistically significantly higher than that of C and OB girls. Statistically significant (P<0.0001) negative correlations between the serum concentrations of omentin-1 and body weight (r=−0.73), BMI (r=−0.75), standard deviation score for body mass index (BMI-SDS) (r=−0.75), insulin (r=−0.81) and HOMA-IR index (r=−0.82) were seen in the entire examined population. We conclude, that omentin-1 is the nutritional marker reflecting body weight and insulin resistance. Our findings support the hypothesized role of omentin in maintenance of body weight and regulation of appetite and suggest the adaptation of its secretion to body weight and glucose metabolism.


2004 ◽  
Vol 89 (8) ◽  
pp. 4053-4061 ◽  
Author(s):  
Antje Böttner ◽  
Jürgen Kratzsch ◽  
Grit Müller ◽  
Thomas M. Kapellen ◽  
Susann Blüher ◽  
...  

Adiponectin is an adipocytokine with profound antidiabetic and antiatherogenic effects that is decreased in obesity. With the increasing prevalence of obesity and the emergence of related disorders, including type 2 diabetes in children, the regulation of adiponectin and its relationship to childhood obesity is of great interest. In this study we aimed to elucidate the impact of gender, pubertal development, and obesity on adiponectin levels in children. We investigated two phenotypically characterized cohorts of 200 normal weight and 135 obese children and adolescents covering a wide range of age (3.4–17.9 yr) and body mass index (−2.1 to +4.8 sd score). In healthy lean boys, adiponectin levels significantly declined in parallel with physical and pubertal development, subsequently leading to significantly reduced adiponectin levels in adolescent boys compared with girls (5.6 ± 0.5 vs. 7.1 ± 0.5 mg/liter; P = 0.03). This decline was inversely related to testosterone (r = −0.42; P &lt; 0.0001) and dehydroepiandrosterone sulfate (r = −0.20; P = 0.0068) serum concentrations and may account for the gender differences seen in adults. Using a stepwise forward multiple regression model, pubertal stage was the strongest independent predictor of adiponectin (r2 = 0.206; P &lt; 0.0001), with additional influences of body mass index sd score and testosterone. Adiponectin levels were decreased in obese children and adolescents compared with lean peers of corresponding age and pubertal stage (5.18 vs. 7.13 mg/liter; P = 0.015). In obese children, adiponectin levels were closely associated with parameters related to the metabolic syndrome, such as insulin resistance, hyperinsulinemia, blood pressure, and uric acid, in univariate and multivariate analyses, with the insulin sensitivity index being the strongest independent parameter identified by stepwise forward multiple regression (r2 = 0.226; P &lt; 0.0001). Hence, there is a strong association of adiponectin serum concentrations with obesity, pubertal development, and metabolic parameters in children indicating epidemiological and pathophysiological relevance already in childhood.


Metabolism ◽  
1991 ◽  
Vol 40 (2) ◽  
pp. 187-190 ◽  
Author(s):  
G. De Pergola ◽  
V.A. Giagulli ◽  
G. Garruti ◽  
M.R. Cospite ◽  
F. Giorgino ◽  
...  

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