scholarly journals Perfluoroalkyl Substances and Maternal Thyroid Hormones in Early Pregnancy; Findings in the Danish National Birth Cohort

2019 ◽  
Vol 127 (11) ◽  
pp. 117002 ◽  
Author(s):  
Kosuke Inoue ◽  
Beate Ritz ◽  
Stine Linding Andersen ◽  
Cecilia Høst Ramlau-Hansen ◽  
Birgit Bjerre Høyer ◽  
...  
2019 ◽  
Vol 127 (1) ◽  
pp. 017004 ◽  
Author(s):  
Andreas Ernst ◽  
Nis Brix ◽  
Lea Lykke Braskhøj Lauridsen ◽  
Jørn Olsen ◽  
Erik Thorup Parner ◽  
...  

2020 ◽  
Vol 264 ◽  
pp. 114557 ◽  
Author(s):  
Ruxianguli Aimuzi ◽  
Kai Luo ◽  
Rong Huang ◽  
Xiaona Huo ◽  
Min Nian ◽  
...  

2016 ◽  
Vol 101 (6) ◽  
pp. 2484-2492 ◽  
Author(s):  
Peter Laurberg ◽  
Stine Linding Andersen ◽  
Peter Hindersson ◽  
Ellen A. Nohr ◽  
Jørn Olsen

2010 ◽  
Vol 32 (10) ◽  
pp. 948-955 ◽  
Author(s):  
Mehrnaz Salehidobakhshari ◽  
Fiona Bamforth ◽  
Igor Burstyn

2016 ◽  
Vol 174 (2) ◽  
pp. 203-212 ◽  
Author(s):  
Stine Linding Andersen ◽  
Jørn Olsen ◽  
Peter Laurberg

ObjectiveThyroid disorders are common in women of reproductive age, but the exact burden of disease before, during and after a pregnancy is not clear. We describe the prevalence of thyroid disease in women enrolled in the Danish National Birth Cohort (DNBC) and investigate some of its risk factors.DesignPopulation-based study within the DNBC, which included 101 032 pregnancies (1997–2003).MethodsWe studied women enrolled in the DNBC who gave birth to a live-born child. Information on maternal thyroid disease (hyperthyroidism, hypothyroidism, benign goiter/nodules, thyroid cancer, and other) before, during and up to 5 years after the woman's first pregnancy in the cohort was obtained from self-report (telephone interview in median gestational week 17) and from nationwide registers on hospital diagnosis of thyroid disease/thyroid surgery (from 1977) and prescriptions of thyroid drugs (from 1995).ResultsOf the 77 445 women studied, 3018 (3.9%) were identified with an onset of thyroid disease before (2.0%), during (0.1%) or in the 5-year period after the pregnancy (1.8%). During the pregnancy, 153 (0.2%) women received antithyroid drugs and 365 (0.5%) received thyroid hormone for hypothyroidism (83 after previous hyperthyroidism, 42 after previous surgery for benign goiter/nodules or thyroid cancer). Significant risk factors for maternal thyroid disease were age, parity, origin, iodine intake, smoking, alcohol, and BMI.ConclusionsAround 4% of Danish pregnant women had either a history of thyroid disease or thyroid disease during pregnancy or were diagnosed with thyroid disease for the first-time in the years following a pregnancy. The spectrum of thyroid disease was influenced by demographic and environmental factors.


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