scholarly journals Endocrine Disruptors in the Workplace, Hair Spray, Folate Supplementation, and Risk of Hypospadias: Case–Control Study

2009 ◽  
Vol 117 (2) ◽  
pp. 303-307 ◽  
Author(s):  
Gillian Ormond ◽  
Mark J. Nieuwenhuijsen ◽  
Paul Nelson ◽  
Mireille B. Toledano ◽  
Nina Iszatt ◽  
...  
2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
M Fiore ◽  
P Zuccarello ◽  
M Gulisano ◽  
M Monteleone ◽  
G Bonaccorso ◽  
...  

Abstract Background BPA and DEHP are endocrine disruptors. BPA-G and MEHP are their main metabolites. The main exposure route for human is the diet. Endometriosis is a pathology with uncertain etiopathogenesis, characterized by disturbances in sex hormones balance with a prevalence in women ranged from 1% to 7% in women aged 15-45 years. Methods A case-control study should highlight a possible relationship between exposure to DEHP and BPA and endometriosis. Patients (n = 40) with a surgical diagnosis of endometriosis will compose the group of cases; healthy women (n = 40) will compose the control group. Cases and controls will be studied by means of questionnaires and by means of urinary analysis of these endocrine disruptors concentration. Results BPA values ranged between 0.05-8.55 and 0.05-1.84 in cases and in controls, respectively; BPA-G values ranged between 0.05-16.1 and 0.05-7.38 in cases and in controls, respectively; total BPA values ranged between 0.05-3.26 and 0.05-3.51 in cases and in controls, respectively. DEHP values ranged between 13.63-57.78 and 16.66-61.93 in cases and in controls, respectively; MEHP values ranged between 1.74-6.16 and 4.26-14.16 in cases and in controls, respectively; total DEHP ranged between 15.27-63.93 and 21.72-72.73 in cases and in controls, respectively. A reverse correlation was found between endometriosis and phthalates, while a direct correlation was found between BPA and endometriosis. Conclusions The direct correlation between BPA and endometriosis suggests the decreasing the use of plasticizer in food packaging and the importance to implement interventions and strategy to minimize exposure. The reverse correlation between endometriosis and DEHP could be explained by the small size of sample and by the monitoring of urine that are representative of a short-time exposure. Key messages Improve epidemiological studies with analysis of alternative matrices that are more representative of long-time exposure. Implement interventions and strategy to minimize exposure to plasticizer.


2011 ◽  
Vol 26 (3) ◽  
pp. 241-246 ◽  
Author(s):  
Roumi Deb ◽  
Jyoti Arora ◽  
Sanjenbam Yaiphaba Meitei ◽  
Sangeeta Gupta ◽  
Vanita Verma ◽  
...  

2012 ◽  
Vol 11 (1) ◽  
Author(s):  
James T Brophy ◽  
Margaret M Keith ◽  
Andrew Watterson ◽  
Robert Park ◽  
Michael Gilbertson ◽  
...  

Epidemiology ◽  
2007 ◽  
Vol 18 (Suppl) ◽  
pp. S86
Author(s):  
G Ormond ◽  
M Nieuwenhuijsen ◽  
P Nelson ◽  
N Iszatt ◽  
P Elliott

2007 ◽  
Vol 6 (1) ◽  
Author(s):  
Stephen L Wood ◽  
John J Jarrell ◽  
Cheryl Swaby ◽  
Sui Chan

2001 ◽  
Vol 120 (5) ◽  
pp. A657-A658
Author(s):  
A CATS ◽  
E BLOEMENA ◽  
E SCHENK ◽  
I CLINICS ◽  
S MEUWISSEN ◽  
...  

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