scholarly journals Biomonitoring Studies Should Be Used by Regulatory Agencies to Assess Human Exposure Levels and Safety of Bisphenol A

2010 ◽  
Vol 118 (8) ◽  
pp. 1051-1054 ◽  
Author(s):  
Laura N. Vandenberg ◽  
Ibrahim Chahoud ◽  
Vasantha Padmanabhan ◽  
Francisco J.R. Paumgartten ◽  
Gilbert Schoenfelder
Keyword(s):  
Bisphenol A ◽  
Human Exposure ◽  
Regulatory Agencies ◽  
Exposure Levels

scholarly journals Origins of Risk Assessment in Food Safety Decision Making

1988 ◽  
Vol 7 (4) ◽  
pp. 539-542 ◽  
Author(s):  
Joseph V. Rodricks
Keyword(s):  
Risk Assessment ◽  
Decision Making ◽  
Human Exposure ◽  
Driving Forces ◽  
Quantitative Risk Assessment ◽  
Regulatory Agencies ◽  
Decision Making Process ◽  
Commercially Important ◽  
Exposure Levels ◽  
Almost All

FDA's efforts during the early 1970s to establish acceptable food exposure levels for carcinogenic animal drugs such as diethylstilbestrol (DES) led the agency to incorporate quantitative risk assessment into its decision-making process. During the nearly two decades since FDA first introduced risk assessment as a regulatory tool, its uses have been expanded to almost all areas of chemical regulation. The major driving forces behind this expansion have been (1) the need to deal systematically with the large number of commercially important chemicals that have been identified as animal carcinogens and that have been found to occur widely in the environment and (2) the large number of laws that now require regulatory agencies to establish limits on human exposure to these substances.

scholarly journals A novel method for rapid and quantitative detection of bisphenol A in urine

2020 ◽  
Author(s):  
Aleksandra Rutkowska ◽  
Aleksandra Olsson ◽  
Jacek Namieśnik ◽  
Andrzej Milewicz ◽  
Jan Krzysztof Ludwicki ◽  
...  
Keyword(s):  
Bisphenol A ◽  
Human Exposure ◽  
Hormone Receptors ◽  
Low Cost ◽  
Medical Diagnostics ◽  
Quantitative Detection ◽  
Adverse Health Effects ◽  
Increased Risk ◽  
Novel Method ◽  
Lifestyle Diseases

Bisphenol A (BPA) is classified as an endocrine disruptor (ED) and it can interact with variety of hormone receptors leading to hormonal disruption and increased risk of various adverse health effects. Reducing human exposure to BPA is one of the main challenges of public health, as it is constantly present in daily life. A low-cost and commonly applied method to enable determination of BPA in the patient's body has yet to be developed. Currently available techniques are expensive, time-consuming, and require access to highly equipped analytical chemistry laboratories. Here we describe a fast and cheap engineered lateral flow assay of our design, to detect of BPA in urine samples. The technology not only provides an opportunity to perform rapid medical diagnostics without the need for an access to the central laboratory but also a means for self-diagnosis by the patient. The addition of β-glucuronidase improves the sensitivity of detection as it releases the free BPA from glucuronide complexes in urine. This invention may become a demonstrated analytical means for lowering human exposure to BPA and probably also to other EDs and consequently, may be useful in decrease of the risk for several lifestyle diseases.

Levels of bisphenol-A in different paper products in Guangzhou, China, and assessment of human exposure via dermal contact

2015 ◽  
Vol 17 (3) ◽  
pp. 667-673 ◽  
Author(s):  
Ruifang Fan ◽  
Biyan Zeng ◽  
Xiaosu Liu ◽  
Chao Chen ◽  
Qinwei Zhuang ◽  
...  
Keyword(s):  
Bisphenol A ◽  
Human Exposure ◽  
Dermal Contact ◽  
Beverage Container ◽  
Food And Beverage

Bisphenol A (BPA) is a chemical widely used both in plastics production as a food and beverage container and in thermal papers as a color developer.

Pharmaceuticals and endocrine disruptors in raw and cooked seafood from European market: Concentrations and human exposure levels

2018 ◽  
Vol 119 ◽  
pp. 570-581 ◽  
Author(s):  
Diana Álvarez-Muñoz ◽  
Sara Rodríguez-Mozaz ◽  
Silke Jacobs ◽  
Albert Serra-Compte ◽  
Nuria Cáceres ◽  
...  
Keyword(s):  
Endocrine Disruptors ◽  
Human Exposure ◽  
European Market ◽  
Exposure Levels

Review of the toxicology, human exposure and safety assessment for bisphenol A diglycidylether (BADGE)

2004 ◽  
Vol 21 (9) ◽  
pp. 905-919 ◽  
Author(s):  
A. Poole ◽  
P. van Herwijnen ◽  
H. Weideli ◽  
M. C. Thomas ◽  
G. Ransbotyn ◽  
...  
Keyword(s):  
Bisphenol A ◽  
Human Exposure ◽  
Safety Assessment

Levels of bisphenol-A in thermal paper receipts from Belgium and estimation of human exposure

2012 ◽  
Vol 435-436 ◽  
pp. 30-33 ◽  
Author(s):  
Tinne Geens ◽  
Leo Goeyens ◽  
Kurunthachalam Kannan ◽  
Hugo Neels ◽  
Adrian Covaci
Keyword(s):  
Bisphenol A ◽  
Human Exposure ◽  
Thermal Paper

Estimate of safe human exposure levels for lunar dust based on comparative benchmark dose modeling

2013 ◽  
Vol 25 (5) ◽  
pp. 243-256 ◽  
Author(s):  
John T. James ◽  
Chiu-Wing Lam ◽  
Patricia A. Santana ◽  
Robert R. Scully
Keyword(s):  
Human Exposure ◽  
Benchmark Dose ◽  
Lunar Dust ◽  
Exposure Levels
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