Prevalence and Patterns of Anterior Segment Dysgenesis among Children with Corneal Opacity in Cairo University Specialized Pediatric Hospital

Author(s):  
Omar Mohamed El Zawahry ◽  
Amanne Feisal Esmael ◽  
Sameh Hassan Abdelbaky
2018 ◽  
Vol 55 (4) ◽  
pp. 584-590 ◽  
Author(s):  
Lorelei L. Clarke ◽  
Kevin D. Niedringhaus ◽  
K. Paige Carmichael ◽  
M. Kevin Keel ◽  
Heather Fenton

Congenital ocular abnormalities in cervids have been previously reported as individual cases from various regions of the United States and include microphthalmia, anophthalmia, congenital cataracts, dermoids, and colobomata. A common underlying cause for these abnormalities, such as nutritional deficiencies, environmental toxin exposures, or genetic mutations, has not been established. This retrospective study summarized and compared cases of suspected congenital ocular abnormalities in free-ranging white-tailed deer ( Odocoileus virginianus) submitted to the Southeastern Cooperative Wildlife Disease Study (SCWDS) in Athens, Georgia, to the preexisting literature. Of 3645 accessions of white-tailed deer submitted to SCWDS, 15 qualifying case records were found. An additional 15 cases were reported previously in the literature. Conditions described in SCWDS cases included microphthalmia (8/15), congenital cataracts (3/15), anophthalmia (2/15), colobomata (1/15), anterior segment dysgenesis (1/15), ectopic lacrimal gland tissue (1/15), and congenital blindness with corneal opacity (1/15). Most (11/15; 73%) of the SCWDS cases were male fawns with an average age of 4 months at presentation, consistent with previously described cases. Most animals had bilateral abnormalities with few extraocular congenital abnormalities, also consistent with existing reports. Cases were variably tested for various infectious agents at the time of submission; 2 cases were seropositive for bluetongue virus. Spatiotemporal clustering of cases was not evident. This study provided a concise and systematic summary of known existing cases of congenital ocular defects in fawns but did not identify a cause.


Author(s):  
N. I. Latyshevskaya ◽  
M. A. Alborova ◽  
L. A. Davydenko ◽  
A. V. Belyaevа

Introduction. The profession of “machine operator in metalworking”, one of the most common professions in various industries, characterized by a large volume of abrasive operations, accompanied by dust formation, which creates a potential for the occurrence of diseases of the visual organ.The aim of the study is to provide a hygienic assessment of working conditions and occupational risk of visual organ pathology in metalworking machine operators.Materials and methods. Observation groups — machine operators for metalworking of two training groups (experience up to 5 years, experience of 6–20 years). Two comparison groups (administrative and technical personnel of the enterprise) are formed according to the same age-experience principle.Results. The working conditions of machine operators were classified as class 3.2. taking into account the severity and intensity of the work process and the noise level (80 dBA) in the workplace. Nitrogen oxide, carbon monoxide, and manganese were registered in the air of the working area in concentrations below the permissible concentration (PC), and the aerosol dihydroxide was registered above the PC in 25.8% of cases. In the main working groups, diseases of the anterior segment of the eye were more often registered, among which dry eye syndrome (DYS) prevailed (94.1%), chronic blepharoconjunctivitis (79.9%), persistent corneal opacification (21.7%). There was an increase in the prevalence of detected diseases with an increase in work experience (p≤0.05). In machine operators, the frequency of inhibition of lacrimal formation and decreased stability of the tear film was recorded significantly more often, with increasing work experience, the degree of violation of lacrimal formation and stability of the tear film increased. The chances of detecting pathology of the anterior segment of the eye in machine operators are 5.9 and 3.5 times higher than in the comparison group. There are different forces of connection, increasing with the increase of work experience in the profession, between the working conditions of machine operators and the occurrence of SHG (relatively strong), with chronic blepharoconjunctivitis and persistent corneal opacity (medium strength), which suggests the professional conditionality of this pathology.Conclusions. The results obtained suggest that the pathology of the anterior segment of the eye is professionally conditioned in metalworking machine operators and necessitate the introduction of preventive measures aimed at protecting the visual organ.


2004 ◽  
Vol 25 (4) ◽  
pp. 277-283 ◽  
Author(s):  
S.M. Quinn ◽  
G.C.M. Black ◽  
S. Biswas ◽  
J. Clayton-Smith ◽  
I.C. Lloyd

1996 ◽  
Vol 210 (6) ◽  
pp. 361-366 ◽  
Author(s):  
Charlise A. Gunderson ◽  
Robert Stone ◽  
Robert Peiffer ◽  
Sharon Freedman

2016 ◽  
Vol 95 (5) ◽  
pp. 537-541 ◽  
Author(s):  
Anastasia V. Pilat ◽  
Viral Sheth ◽  
Ravi Purohit ◽  
Frank A. Proudlock ◽  
Samira Anwar ◽  
...  

2021 ◽  
Vol 62 (12) ◽  
pp. 1667-1671
Author(s):  
Seongmi Kim ◽  
Hye Jin Lee ◽  
Ahnul Ha ◽  
Jong Young Lee ◽  
Jinho Jeong

Purpose: We report a case of keratitis that improved after removal of a causative plant foreign body from below the posterior surface of an opaque cornea. The foreign body was revealed by anterior segment optical coherence tomography (AS-OCT) and gonioscopy.Case summary: A 79-year-old woman was referred with an impression of left-eye keratitis; the eye had been injured by a branch of a tangerine tree 1 month prior. She had been given the usual topical antibiotics by a local clinic, but they were ineffective. At her initial visit, her visual acuity was only hand motion in the left eye; slit-lamp examination revealed a 3 × 3-mm corneal infiltration with a hypopyon in the anterior chamber. Despite administration of strong topical antibiotics on an hourly basis, the corneal lesion worsened. AS-OCT and gonioscopy revealed a small foreign body below the posterior surface of the cornea; this was surgically removed. The corneal opacity and corneal epithelial defects dramatically improved, and the hypopyon disappeared.Conclusions: The possibility of a residual foreign body should be considered if trauma precedes infectious keratitis that does not improve with conventional treatment and the posterior surface of the cornea is not visible because of corneal opacity. In such a case, AS-OCT and gonioscopy can be useful.


Author(s):  
Ozlem Dikmetas ◽  
Pelin Ozlem Simsek Kiper ◽  
Mehmet C. Mocan ◽  
Eda G. Utine ◽  
Koray Boduroglu ◽  
...  

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