Histomorphometric Analysis of Bone Deposition at Ti Implant Surface Dip - Coated with Hydroxyapatite ( in Vivo Study )

2013 ◽  
Vol 25 (2) ◽  
pp. 70-75
Author(s):  
Athraa Y. Al-Hijazi ◽  
Thair L. Al-Zubaydi ◽  
Eman I. Mahdi
2014 ◽  
Vol 9 (1) ◽  
pp. 12-17 ◽  
Author(s):  
Bushra Habeeb Al-Molla ◽  
Nada Al-Ghaban ◽  
Abbas Taher

2019 ◽  
Vol 20 (13) ◽  
pp. 3267 ◽  
Author(s):  
Eugenio Velasco-Ortega ◽  
Ivan Ortiz-García ◽  
Alvaro Jiménez-Guerra ◽  
Loreto Monsalve-Guil ◽  
Fernando Muñoz-Guzón ◽  
...  

The surface modifications of titanium dental implants play important roles in the enhancement of osseointegration. The objective of the present study was to test two different implant surface treatments on a rabbit model to investigate the osseointegration. The tested surfaces were: a) acid-etched surface with sandblasting treatment (SA) and b) an oxidized implant surface (OS). The roughness was measured by an interferometeric microscope with white light and the residual stress of the surfaces was measured with X-ray residual stress Bragg–Bentano diffraction. Six New Zealand white rabbits were used for the in vivo study. Implants with the two different surfaces (SA and OS) were inserted in the femoral bone. After 12 weeks of implantation, histological and histomorphometric analyses of the blocks containing the implants and the surrounding bone were performed. All the implants were correctly implanted and no signs of infection were observed. SA and OS surfaces were both surrounded by newly formed trabeculae. Histomorphometric analysis revealed that the bone–implant contact % (BIC) was higher around the SA implants (53.49 ± 8.46) than around the OS implants (50.94 ± 16.42), although there were no significant statistical differences among them. Both implant surfaces (SA and OS) demonstrated a good bone response with significant amounts of newly formed bone along the implant surface after 12 weeks of implantation. These results confirmed the importance of the topography and physico–chemical properties of dental implants in the osseointegration.


Author(s):  
Nicolas Rousseau ◽  
Inès Msolli ◽  
Patrick Chabrand ◽  
Arnaud Destainville ◽  
Olivier Richart ◽  
...  

Materials ◽  
2021 ◽  
Vol 14 (8) ◽  
pp. 1830
Author(s):  
Mastrangelo Filiberto ◽  
Botticelli Daniele ◽  
Bengazi Franco ◽  
Scarano Antonio ◽  
Piattelli Adriano ◽  
...  

Objective: Evaluation of the in vivo bone response of two innovative titanium surfaces ytterbium laser active fiber obtained (L1-L2) compared to a sandblasted and acid etched (SBAE) during early phase of osseointegration. Material and Methods: Three implant groups with the same macroscopic features were obtained (L1-L2-SBAE) to promote specific surface characteristics. Scanning electron microscopy, profilometric evaluation, X-ray spectrometry, and diffraction analysis were performed. For each group, six implants were placed in the tibiae of three Peli Buey sheep, and histologic, histomorphometric analysis, bone to implant contact (BIC), and the Dynamic Osseointegration index (DOI) were performed. Results: During the early phases of osseointegration, the histological and histomorphometric results showed significant differences between L1-L2-SBAE implants. At 15 and 30 days, histological analysis detected a newly bone formation around all specimens with an higher vital bone in L2 compared to L1 and SBAE both in cortical and in poor-quality marrow bone. At same time, histomorphometric analysis showed significantly higher BIC values in L2 (42.1 ± 2.6 and 82.4 ± 2.2) compared to L1 (5.2 ± 3.1 and 56.2 ± 1.3) and SBAE (23.3 ± 3.9 and 77.3 ± 0.4). DOI medium value showed a higher rate in L2 (2.83) compared to SBAE (2.60) and L1 (1.91). Conclusions: With the limitations of this pilot study, it is possible to assess that the titanium surface characteristics, and not the technologies used to obtain the modification, played a crucial role during the osseointegration process. Histological, histomorphometric, BIC, and DOI evaluation showed a significantly higher rate in L2 specimens compared to others, confirming that the implant surface could increase the bone response in cortical or marrow poor quality bone during the initial phases of osseointegration.


Author(s):  
Yuhao Zhu ◽  
Antian Xu ◽  
Chuan Zhou ◽  
Yefeng Wu ◽  
Guofen Lin ◽  
...  

Storage in aqueous solution or ultraviolet (UV) irradiation  can  re t ain or regain the hydrophilicity of titanium implant surface.  In this study, t hree types of commercial titanium implants were used : ZBL (ZDI Bone  L evel ® ), CEL (C-tech Esthetic Line ® ) , and modSLA (Straumann SLActive ® ). ZBL and CEL implants were treated with UV irradiation for 4 h. Surface characterization of the four groups (ZBL, ZBL-UV, CEL-UV, modSLA)  was  evaluated by scanning electron microscopy and contact angle measurements. The  in vivo bone response  was  evaluated by removal torque (RTQ) tests and histomorphometric analysis  at  3, 6 , and 12 weeks post-implantation. A total of 144 implants and 36 rabbits were used for experiments according to a previously established randomization sequence. The  ZBL-UV, CEL-UV , andmodSLA groups were hydrophilic, and nanostructures were observed on  the  modSLA implant surface.ModSLA achieved better  RTQ value than ZBL at 12 weeks ( p <0.05). For histomorphometric analysis, ZBL-UV and CEL-UV implants showed higher bone area values in  the  cancellous bone zone at 6 weeks than  did  modSLA and ZBL  implants  ( p <0.05).In  the  cortical bone zone, all groups showed comparable bone-to-implant contact at all healing time points ( p >0.05).Both storage in saline  and UV irradiation could retain or provoke hydr o philic surfaces and improve osseointegration. Compared to storage in saline, UV irradiation displayed slight advantages in promoting new bone formation in cancellous bone zone at  an  early stage.


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