scholarly journals Obesity 2021: Current Clinical Management of a Chronic, Serious Disease

2021 ◽  
Vol 70 (6 Supplement) ◽  
Author(s):  
Kushner

LEARNING OBJECTIVES At the end of the activity, participants will be able to: • Recognize obesity as a chronic, relapsing, serious disease warranting long-term management and early intervention to minimize disease burden and decrease associated morbidity and mortality. • Destigmatize obesity to initiate and enhance patient engagement. • Apply guideline-recommended care for screening, diagnosis, and individualized treatment of adults and others with obesity. • Incorporate practical practice management strategies.

2021 ◽  
Vol 17 (1) ◽  
Author(s):  
Konrad Bork ◽  
John T. Anderson ◽  
Teresa Caballero ◽  
Timothy Craig ◽  
Douglas T. Johnston ◽  
...  

Abstract Background Hereditary angioedema (HAE) is a rare disease characterized by unpredictable, potentially life-threatening attacks, resulting in significant physical and emotional burdens for patients and families. To optimize care for patients with HAE, an individualized management plan should be considered in partnership with the physician, requiring comprehensive assessment of the patient’s frequency and severity of attacks, disease burden, and therapeutic control. Although several guidelines and consensus papers have been published concerning the diagnosis and treatment of HAE, there has been limited specific clinical guidance on the assessment of disease burden and quality of life (QoL) in this patient population. Practical guidance is critical in supporting effective long-term clinical management of HAE and improving patient outcomes. The objective of this review is to provide evidence-based guidelines for an individualized assessment of disease burden and QoL in patients with HAE. Methods A consensus meeting was held on February 29, 2020, consisting of 9 HAE experts from the United States and Europe with extensive clinical experience in the treatment of HAE. Consensus statements were developed based on a preliminary literature review and discussions from the consensus meeting. Results Final statements reflect the consensus of the expert panel and include the assessment of attack severity, evaluation of disease burden, and long-term clinical management of HAE caused by C1-esterase inhibitor deficiency. Patient-reported outcome measures for assessing HAE attack severity and frequency are available and valuable tools; however, attack frequency and severity are insufficient markers of disease severity unless they are evaluated in the broader context of the effect on an individual patient’s QoL. QoL assessments should be individualized for each patient and minimally, they should address the interference of HAE with work, school, social, family, and physical activity, along with access to and burden of HAE treatment. Advances in HAE therapies offer the opportunity for comprehensive, individualized treatment plans, allowing patients to achieve minimal attack burden with reduced disease and treatment burden. Conclusion This consensus report builds on existing guidelines by expanding the assessment of disease burden and QoL measures for patients with HAE.


2002 ◽  
Vol 5 (4) ◽  
pp. 312-328 ◽  
Author(s):  
Ron Goeree ◽  
Bernie J. O'Brien ◽  
Gordon Blackhouse ◽  
John Marshall ◽  
Andrew Briggs ◽  
...  

1995 ◽  
Vol 1 (1) ◽  
pp. 74
Author(s):  
Martin Knapp

Advice on enuresis has been provided by a range of individuals. Many myths and misunderstandings have been responsible for the confusing range of opinions given to those who seek help. Management should be based on an understanding of the physiology of the condition and the established facts about its treatment. There is still a lack of awareness about how effective are the management strategies now proposed by those who base their practise on the extensive research that is now documented. The best results are obtained with conditioning therapy, when this is supervised and supported. There is an important role for 'wetness' alarms in conditioning. There are now body-worn mini-alarms, established by over a decade of use, that are inexpensive and reliable. There is a decreasing role for tricyclic medication. The recently introduced pharmaceutical Minirin (desmopressin) is useful in short-term management to get dryness on social occasions and, in selected individuals, might have a role in long-term control of enuresis, when conditioning has not been effective. There is an important need to provide advice and treatment facilities for all those with enuresis - a treatable condition.


2007 ◽  
Vol 13 (1) ◽  
pp. 20 ◽  
Author(s):  
Melany H. Chapin ◽  
Mike Maunder ◽  
Katherine E. Horak

Island floras have been subject to catastrophic changes since human colonization; the Hawaiian Islands exemplify this pattern of species decline and ecological change. Archaeological and historic findings support the former existence of coastal, lowland and interior Pritchardia dominated forests. Wild Pritchardia populations are highly fragmented and exhibit poor or absent regeneration in the wild. This study records seed predation, goat grazing, pig damage, and human harvesting on six wild populations of three species and outlines requirements for the long-term management of wild populations. Only one population of the six studied was found to contain seedlings. Recommended conservation management strategies are outlined.


Author(s):  
Adam B. Rosen ◽  
Elizabeth Wellsandt ◽  
Mike Nicola ◽  
Matthew A. Tao

ABSTRACT Patellar tendinopathy is a common, yet misunderstood pathoetiology afflicting a variety of patient populations. This lack of unified understanding affects the capability of clinicians to provide effective treatment interventions. Patients with tendinopathy often report long-term and low to moderate levels of pain, diminished flexibility, and strength, as well as decreased physical function. Load-management strategies combined with exercise regimens focused on progressive tendon loading are the most effective treatment option for patients with patellar tendinopathy. This review will provide an evidence-based approach to patellar tendinopathy, including its pathoetiology, evaluation, and treatment strategies.


2019 ◽  
Vol 24 (12) ◽  
pp. 576-579 ◽  
Author(s):  
Debbie Provan

Overweight and obesity are known risk factors for the development of lymphoedema, and are also well-recognised factors complicating the management of lymphoedema. However, a degree of uncertainty remains regarding the way in which obesity impacts upon the condition, and there is little detail about the practical application of weight management strategies in the population with lymphoedema. This article provides the background for ongoing research into the association between lymphoedema management and obesity. It is hoped that this research will provide important insights into the long-term management of lymphoedema.


2003 ◽  
Vol 48 (1) ◽  
pp. 147-154 ◽  
Author(s):  
C. Lampert

Nutrients are a limited resource and call for management. A sustainable nutrient management strategy reintegrates nutrients in the environment without accumulating harmful substances above an acceptable level. In this study a methodology to assess the environmental compatibility was developed. For this assessment both the (i) enrichment of pollutants in the soils and (ii) the area specific nutrient demand of the crops were taken into account. The method considers, that products applied on soils also contain stable substances, and as a consequence the accumulation of pollutants diminishes. Additionally, it is considered, that increasing substance concentrations in the soil will lead to an increase of substance flows out of the soil by percolation, plant-removal (and erosion). In practice long term management strategies are restricted by the time span considered, the accepted accumulation of substances, the plants real needs and legal constraints. The rating of various goods can be made with the ratio of the added nutrients, considering the pollution criteria, the legal constraints and the plants real needs.


2012 ◽  
Vol 50 (No. 11) ◽  
pp. 510-513 ◽  
Author(s):  
J. Simon

About 15% of the area of the Czech Republic is classified as territories with special status of protection, most of which is covered with forests. At present, at the time of integration of the country into the European structures, an increase in the area of such territories by approximately 20% is expected. The territories show significant variation of protection objectives, management restrictions, profound differentiation in natural conditions, structure of ownership and different levels of damage, especially that caused by anthropogenic pressure. This situation requires the formulation of long-term management strategies. The problem can be solved in the following successive steps: formulation of variants and alternatives of management strategies based on a retrospective analysis of forest development; prognosis of the forest condition development after application of the individual management strategies on the basis of growth and development simulations; addition of technological and economical bases; selection of optimal variants and alternatives from the viewpoint of the fulfilment of the owner’s management goals, in accordance with the principles of forest policy and from the viewpoint of the fulfilment of the protection objective formulated for a specific territory with special status of protection. A set of methods for following the above-mentioned steps is specified in the presented contribution.


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