Clinical and epidemiological features and residual manifestations of serous enteroviralmeningitis in children in North Ossetia-Alania

2016 ◽  
Vol 21 (32) ◽  
pp. 46-51
Author(s):  
Калоева ◽  
Zinaida Kaloeva ◽  
Гуссоева ◽  
I. Gussoeva ◽  
Албегова ◽  
...  

The article presents the analysis of the epidemiological, clinical and laboratory features of serous meningitis enteroviral etiology in children hospitalized at the RCCH of Vladikavkaz in 2008–2012. We have also studied the residual manifestations of enteroviral meningitis in 44 patients in the early period of convalescence. The study showed that of RNO-Alania typical summer – autumn seasonality of serous meningitis enteroviral etiology in children. The central nervous system caused by enteroviruses more often develops in children of preschool and school age. The clinical picture of enteroviral meningitis remains a leading hypertension – hydrocephalic syndrome. In the early period of convalescence enteroviral meningitis in children often formed cerebro-asthenic, hypertension, neurosis-like syndromes and syndrome immune dysfunction.

2018 ◽  
Vol 17 (3) ◽  
pp. 11-16
Author(s):  
G. P. Martynova ◽  
N. S. Strashnikova ◽  
I. A. Kutisheva ◽  
A. B. Belkina ◽  
A. V. Karasev

Objective. To reveal the clinical and epidemiological features of еnterovirus meningitis (EVM) in 140 children of Krasnoyarsk in the period of seasonal rise of morbidity in 2017.Materials and methods. For the etiological interpretation of the enterovirus infection (EVI), a molecular biological and virological study of the cerebrospinal fluid, two samples of feces, a swab from the oropharynx, the contents of the vesicles was carried out. Statistical processing of data was carried out using the PASW Statistics 17.0 program.Results. In the Krasnoyarsk Territory, an annual increase in the incidence of EVI is registered, exceeding the average for the country. Serous meningitis is traditionally the main clinical form of EVI. Among the observed patients with EVM, the main group consisted of preschool children (32.9%) and school age (30%), mainly organized in children's groups (84.3%), and the summer-autumn seasonality of the disease remains. Meningitis was observed in 82.8% of patients, meningitis combined with exanthema — in 10%, with herpangina — in 2.1%, with myalgia  — in isolated cases . Mediastinal forms of the disease predominated (96.4% — 135 people), severe forms of the EVM were diagnosed only in 3.6% (5 patients). The clinical picture is traditionally represented by three leading syndromes: intoxication, cerebral and meningeal. The implementation of the epidemic process in 2017 was mainly represented by enteroviruses Coxackie B, B1, B2, B4. Despite the relatively favorable course of the EVM, residual events were in 10% of patients (14 people) at the time of discharge.


2012 ◽  
Vol 17 (3) ◽  
pp. 38-42
Author(s):  
S. N. Eshmolov ◽  
I. G. Sitnikov ◽  
I. M. Melnikov

152 cases of enteroviral meningitis in children aged 3 to 17years treated at the Infectious Diseases Hospital in Yaroslavl have been analyzed. The dominance of moderate forms of the disease with hypertension-hydrocephalic syndrome has been established. The combination with other clinical forms of enteroviral infection was rare, except for reactive pancreatitis. In patients with aseptic meningitis in the acute phase of illness an imbalance of cytokine profile due to increasing the production ofproinflammatory and reduction of the protective role of anti-inflammatory cytokines took place. Despite the relatively favorable course, a high risk of developing functional and organic disorders of the nervous system in a period of convalescence maintained, which creates conditions for the revision and supplement the standard protocols of treatment programs by including in them medicines of etiotropic targeting. The authors have developed regimens and performed the analysis of clinical and immunological efficacy of drugs with antiviral and interferonogenic action - arbidol and amiksin - in the content of complex basic therapy. In addition, the results of outpatient monitoring ofconvalescents 3 months after discharge from hospital have been analyzed. These data justify the need and desirability of inclusion of etiotropic drugs in standards of the basic therapy of enteroviral meningitis in children.


2019 ◽  
Vol 18 (4) ◽  
pp. 43-48
Author(s):  
S. P. Kokoreva ◽  
N. V. Kazartseva ◽  
V. B. Kotlova

In recent years, enterovirus infection (EVI) retains its cyclical nature with an increase in the incidence rate in the Russian Federation in 2000, 2006, 2009, 2013 and 2017. Observation of 41 patients with laboratory-confirmed enteroviral meningitis (EVM) in 2000, 54 children in 2013, and 56 patients in 2018 revealed the clinical and laboratory features of this clinical form of the disease, mainly concerning changes in hemo- and liquorogram parameters, which allowed to trace the evolutionary changes during this infection in children.


2020 ◽  
pp. 49-56
Author(s):  
T. Shirshova

Disorders of the musculoskeletal system in school-age children occupy 1-2 places in the structure of functional abnormalities. Cognitive impairment without organic damage to the central nervous system is detected in 30-56% of healthy school children. Along with the increase in the incidence rate, the demand for rehabilitation systems, which allow patients to return to normal life as soon as possible and maintain the motivation for the rehabilitation process, is also growing. Adaptation of rehabilitation techniques, ease of equipment management, availability of specially trained personnel and availability of technical support for complexes becomes important.


2020 ◽  
pp. 76-79
Author(s):  
N. P. Setko ◽  
E. V. Bulycheva ◽  
O. M. Zhdanova

Objective: The objective is to determine the features of formation of the functional state of the central nervous system (CNS) and cognitive abilities in children and adolescents of the school age.Methods: The study included 300 school children of general education institution of Orenburg. Functional state of CNS was evaluated with variational chronoreflexometry. Cognitive availabilities have been studied with proof-reading test, Landolt ring.Results: From 7–11 y.o. to 16–17 y.o., there was an increase by 1.5 times in parameters of CNS functional state. Students aged from 7–11 y.o. by 12–15 y.o. demonstrated decrease in processing speed by 1.5 times due to increase of cognitive activity to 1.8 times. From 12–15 y.o. by 16–17 y.o., on the contrary, there was an increase of information processing speed by 1.3 times and decrease of cognitive activity by 2.9 times.Conclusions: The detected features of formation of CNS functional state and cognitive abilities in children and adolescents can be taken into account in when organizing personality-oriented training in educational institutions in order to maintain and increase the level of mental performance and academic performance of students. 


2019 ◽  
Vol 11 (1) ◽  
pp. 41-45
Author(s):  
L. V. Pypa ◽  
R. V. Svistilnik ◽  
Yu. N. Lysytsia ◽  
K. Yu. Romanchuk ◽  
I. V. Odarchuk

Aim of work – to analyze the etiological structure, epidemiological structure, social-demographic features and the nature of the development of complications of the central nervous system in aseptic meningitis in children in Khmelnitskyi region for the period 2004-2017.Materials and methods. It was conducted a prospective analysis of 208 cases of aseptic meningitis in children of whom 138 people were boys and 70 people were girls. The etiology of the disease was determined by studying cerebrospinal fluid using PCR method. Complications of the central nervous system were diagnosed on the basis of the clinical picture and CT or MRI scans. The analytical method was used to conduct the analysis of the received data.Results. The highest seasonal increase of the incidence was from August to October and it was 65.6% with its peak in September (24.0%). The clinical picture was characterized by a moderate trend in 71.2% of cases and in 28.8% by a severe course. In 100% of cases the disease began with a fever, headache (83.6%), vomiting (76.9%), abdominal pain with diarrhea (6.2%), epileptic seizures (0.9%). The average level of cytosis was 269.4±196.7 cells/mm3with a predominance of lymphocytes and the average protein level in cerebrospinal fluid was 73 ± 36 mg/dl. The etiological factor was established in 18 (8.6%) patients.Conclusions. Enterovirus remains to be the main pathogen which was determined in 72.2% of cases. The second place was taken by herpes viruses (22.2% of cases), the third place was given to the mumps virus (5.6% of cases) (in etiologically verified cases). In most cases the disease ended in complete recovery but in 47 (22.6%) patients the complications were observed. The prevalence of aseptic meningitis among children in Khmelnitskyi region was 6.2 per 100,000 children, and males outnumbered females by a 2:1 ratio.


2015 ◽  
Vol 7 (16) ◽  
pp. 47-56
Author(s):  
Desy Kumaladewi ◽  
Sugeng Maryanto ◽  
Galeh Septiar Pontang

Stunting is one of the effects of lack of nutrients that lasts a long time. Stunting can occur due to deficiency of macronutrients and macronutrients that play a role in the growth, such as energy, protein, vitamin A and zinc (Zn). The aim of this study was determine the relationship between the intake of energy, protein, vitamin A and zinc (Zn) and the incidences of stunting in children of school age in Candirejo Village This research was The study correlation with cross sectional approach. The population in this study were all first year students in Candirejo village. It obtained 56 children with total sampling method. Method of data taking used microtoise, digital scale and FFQ. Bivariate analysis used Pearson product moment and alternative test of Spearman rho (α=0,05) The average energy intake in children was 86.5% RDA. The average protein intake in children was 106.3% RDA. The average intake of vitamin A in children was 111.9% RDA. The average intake of zinc in children was 64.4% RDA. From 56 childs 37,5% was stunting and 62,5% no stunting. There was no relationship between the intake of energy, protein and vitamin A with the incidences of stunting (p = 0.129, p = 0.139, p = 0.200), and there was a correlation between zinc intake with the incidences of stunting (p = 0.014) There was no relationship between the intake of energy, protein and vitamin A with the incidences of stunting in children of school-age in Candirejo village. There was a relationship between zinc intake with the incidences of stunting in school-age children in the Candirejo village.


1981 ◽  
Vol 54 (2) ◽  
pp. 261-263 ◽  
Author(s):  
Stephen J. Lerman

✓ Two (1%) of 165 episodes of Haemophilus influenzae infection of the central nervous system occurred in patients with cerebrospinal fluid shunts. Both cases were caused by strains that could not be typed. The clinical presentation was similar to that of other forms of shunt infection, yet the pathogenesis may be similar to that of H. influenzae meningitis in children without shunts. Systemic antibiotic therapy, without shunt replacement or intraventricular antibiotic administration, may be more successful in shunt infections caused by H. influenzae than in those caused by other organisms.


2010 ◽  
Vol 2010 ◽  
pp. 1-4 ◽  
Author(s):  
Urs Ehehalt ◽  
Stefan Schmiedel ◽  
Ansgar W. Lohse

Immunosuppression of any kind is a known risk factor for infection withListeria monocytogenes(L. monocytogenes). Particularly, patients with impaired liver function are at increased risk of developing an aggravated course of infection with this bacterial pathogen (see Nolla-Salas et al.; 2002 and Cabellos et al.; 2008). It is a well-known pathogen in immunocompromised patients, but has only seldom been reported following orthotopic liver transplantation. Invasion of the central nervous system presenting as meningitis or meningoencephalitis and bacteremia are the principal clinical manifestations of listerial infections (see Brouwer et al.; 2006). We present an account of a case of a patient who developedL. monocytogenesmeningitis during the early period after liver transplantation.


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