Dynamics of lysozyme activity in the blood of intact female rats and pregnant female rats before and after the labor

2016 ◽  
Vol 21 (32) ◽  
pp. 17-22
Author(s):  
Абрамова ◽  
Marina Abramova ◽  
Алексеев ◽  
Vladimir Alekseev ◽  
Бойченко ◽  
...  
Keyword(s):  
Innate Immunity ◽  
Lysozyme Activity ◽  
Pregnant Female ◽  
Labor Pain ◽  
Female Rats ◽  
Intact Female ◽  
Painful Stimulation ◽  
Before And After ◽  
Immunity Factor ◽  
Term Labor

Labor pain can be the cause of the innate immunity factor, for example activity of lysozyme. It is the purpose of this research.Normative term labor in rats and labor with preceding electrical painful stimulation were accompanied with increase of lysozyme activity in the blood. The level of lysozyme activity was increased earlier and persisted longer in rats with painful irritation.

Dynamics of lysozyme activity in rat’s offspring before and after birth in intact rats and rats with painful stimulation at the day before the birth

2016 ◽  
Vol 21 (32) ◽  
pp. 8-12
Author(s):  
Абрамова ◽  
Marina Abramova ◽  
Алексеев ◽  
Vladimir Alekseev ◽  
Бойченко ◽  
...  
Keyword(s):  
Lysozyme Activity ◽  
Pregnant Female ◽  
Female Rats ◽  
Intact Female ◽  
Painful Stimulation ◽  
Before And After ◽  
Increased Activity ◽  
Stimulation Of ◽  
Intact Rats

Electrical painful stimulation of pregnant female rats at the day before the birth leads to an increased activity of lysozyme in rat’s offspring in the womb. No differences were found between lysozyme activity in the rat’s blood, which were born from intact female rats and female rats with electrical painful stimulation.

scholarly journals Kidney Injury Caused by Preeclamptic Pregnancy Recovers Postpartum in a Transgenic Rat Model

2021 ◽  
Vol 22 (7) ◽  
pp. 3762
Author(s):  
Sarah M. Kedziora ◽  
Kristin Kräker ◽  
Lajos Markó ◽  
Julia Binder ◽  
Meryam Sugulle ◽  
...  
Keyword(s):  
Rat Model ◽  
Renal Damage ◽  
Kidney Injury ◽  
Tissue Growth ◽  
Female Rats ◽  
Male Rats ◽  
Renal Diseases ◽  
Transgenic Rat ◽  
Increased Risk ◽  
Before And After

Preeclampsia (PE) is characterized by the onset of hypertension (≥140/90 mmHg) and presence of proteinuria (>300 mg/L/24 h urine) or other maternal organ dysfunctions. During human PE, renal injuries have been observed. Some studies suggest that women with PE diagnosis have an increased risk to develop renal diseases later in life. However, in human studies PE as a single cause of this development cannot be investigated. Here, we aimed to investigate the effect of PE on postpartum renal damage in an established transgenic PE rat model. Female rats harboring the human-angiotensinogen gene develop a preeclamptic phenotype after mating with male rats harboring the human-renin gene, but are normotensive before and after pregnancy. During pregnancy PE rats developed mild tubular and glomerular changes assessed by histologic analysis, increased gene expression of renal damage markers such as kidney injury marker 1 and connective-tissue growth factor, and albuminuria compared to female wild-type rats (WT). However, four weeks postpartum, most PE-related renal pathologies were absent, including albuminuria and elevated biomarker expression. Only mild enlargement of the glomerular tuft could be detected. Overall, the glomerular and tubular function were affected during pregnancy in the transgenic PE rat. However, almost all these pathologies observed during PE recovered postpartum.

Gonadal hormones organize and modulate the circadian system of the rat

1981 ◽  
Vol 241 (1) ◽  
pp. R62-R66 ◽  
Author(s):  
H. E. Albers
Keyword(s):  
Testosterone Propionate ◽  
Wheel Running ◽  
Activity Rhythm ◽  
Gonadal Hormones ◽  
Circadian System ◽  
Female Rats ◽  
Constant Darkness ◽  
Before And After ◽  
Free Running ◽  
Free Running Period

The circadian wheel-running rhythms of gonadectomized adult male, female, and perinatally androgenized female rats, maintained in constant darkness, were examined before and after implantation of Silastic capsules containing cholesterol (C) or estradiol-17 beta (E). The free-running period of the activity rhythm (tau) before capsule implantation tended to be shorter in animals exposed to perinatal androgen. Administration of C did not reliably alter tau in any group. E significantly shortened tau in 100% of females injected with oil on day 3 of life. In females, injected with 3.5 micrograms testosterone propionate on day 3, and males, E shortened or lengthened tau, with the direction and magnitude of this change in tau inversely related to the length of the individual's pretreatment tau. These data indicate that the presence of perinatal androgen does not eliminate the sensitivity of the circadian system of the rat to estrogen, since estrogen alters tau in a manner that depends on its pretreatment length.

DZIKIR CAN REDUCE LABOR PAIN LEVEL

2021 ◽  
Vol 2 (1) ◽  
pp. 26-30
Author(s):  
Ai Nur Zannah
Keyword(s):  
Physiological Condition ◽  
Active Phase ◽  
Labor Pain ◽  
Pain Level ◽  
Cervical Dilation ◽  
Uterine Contractions ◽  
Before And After ◽  
Quasi Experimental ◽  
Latent Phase ◽  
First Stage Of Labor

Labor pain is a physiological condition that began at the first stage of labor (laten and active phase). Pain comes from uterine contractions and cervical dilation in an attempt to pave the way for birth and encourage babies to be born. Experts find pharmacological and non-pharmacological ways to reduce pain in labor, one of them is Dzikir guided by childbirth helper (midwife). The purpose of this study was to analyze the differences of labor pain level on mother in latent phase before and after applying Dzikir. Subjects were 15 accidentally selected mothers in labor latent phase on March - April in PMB “S” Puger Jember. The design of this study uses a quasi-experimental one group pre-posttest. Results showed significant decreased pain level of mothers after doing Dzikir significantly (Z=-3,578, p≤0.001). In conclusions, there are differences of labor pain level on mother in latent phase before and after applying Dzikir

scholarly journals Soy-Induced Fecal Metabolome Changes in Ovariectomized and Intact Female Rats: Relationship with Cardiometabolic Health

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Victoria J. Vieira-Potter ◽  
Tzu-Wen L. Cross ◽  
Kelly S. Swanson ◽  
Saurav J. Sarma ◽  
Zhentian Lei ◽  
...  
Keyword(s):  
Female Rats ◽  
Cardiometabolic Health ◽  
Intact Female

Pituitary Responsiveness to LH-Releasing Hormone in Intact Female Rats of Different Ages*

Endocrinology ◽  
1972 ◽  
Vol 90 (6) ◽  
pp. 1499-1502 ◽  
Author(s):  
LUCIANO DEBELJUK ◽  
AKIRA ARIMURA ◽  
ANDREW V. SCHALLY
Keyword(s):  
Female Rats ◽  
Intact Female ◽  
Releasing Hormone ◽  
Different Ages ◽  
Lh Releasing Hormone

Effect of Starvation on Pituitary and Serum Follicle-Stimulating Hormone and Luteinizing Hormone Following Ovariectomy in the Rat

1972 ◽  
Vol 50 (8) ◽  
pp. 768-773 ◽  
Author(s):  
E. A. Ibrahim ◽  
B. E. Howland
Keyword(s):  
Luteinizing Hormone ◽  
Pituitary Gland ◽  
Follicle Stimulating Hormone ◽  
Female Rats ◽  
Intact Female ◽  
Pituitary Glands ◽  
Ad Libitum ◽  
Stimulating Hormone

The concentration of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) in serum and pituitary glands was studied in intact female rats and rats that were ovariectomized on day 0 of the experiment and then starved or fed for 2, 4, 7, or 9 days. Ovariectomy resulted in enhanced rates of synthesis and release of FSH and LH as indicated by the significant (P < 0.01) rises in the concentration of both hormones in the pituitary gland and serum.Starvation resulted in a decrease in body and pituitary weight. The concentration of FSH and LH in pituitary glands of starved rats was higher (P < 0.05) than that in fed rats on days 7 and 9. The concentration of FSH and LH in serum of starved rats was increased after ovariectomy but the levels on days 7 and 9 were lower than those of fed rats.These results suggest that the synthesis of FSH and LH was enhanced in both starved and fed rats following ovariectomy while the rate of release of both hormones was decreased at 7 and 9 days of starvation in comparison with rats fed ad libitum.

Effects of chronic estrogen treatment on water exchange in rats

1984 ◽  
Vol 247 (1) ◽  
pp. E101-E110 ◽  
Author(s):  
K. A. Carlberg ◽  
M. J. Fregly ◽  
M. Fahey
Keyword(s):  
Water Exchange ◽  
Daily Intake ◽  
Estradiol Benzoate ◽  
Female Rats ◽  
Intact Female ◽  
Water Turnover ◽  
Ovx Rats ◽  
Concentrate Urine ◽  
Daily Water ◽  
Intake Ratio

Intact female rats implanted subcutaneously with Silastic tubes containing estradiol benzoate (EB) (28.7 micrograms X kg-1 X day-1) for 28 wk had a significantly greater daily intake of water, a higher water-to-food intake ratio, and a greater urine output than untreated control rats. Ovariectomized (OVX) rats also implanted for 14 wk with EB tubes (15 and 36 micrograms X kg-1 X day-1) showed identical results. Dipsogenic responses of the EB-treated rats to isoproterenol (25 micrograms/kg sc), angiotensin II (200 micrograms/kg ip), and hypertonic saline (1 M, 1% of body wt ip) were significantly attenuated. Both intact and OVX rats were subjected to a 24-h dehydration to assess renal concentrating ability. EB-treated rats lost significantly more weight and excreted significantly more urine of lower osmolality than controls. Administration of vasopressin to volume-loaded, EB-treated rats revealed no abnormalities in the ability to concentrate urine to the level of controls. Thus, in spite of a reduced responsiveness to several dipsogenic stimuli, EB-treated rats have an increased daily water turnover apparently related to an inability to concentrate their urine. This in turn may be related to abnormalities in either synthesis or release of antidiuretic hormone or both.

scholarly journals Evaluation of developmental toxicity of guaifenesin using pregnant female rats

2016 ◽  
Vol 48 (3) ◽  
pp. 264 ◽  
Author(s):  
Arham Shabbir ◽  
Sadia Shamsi ◽  
Muhammad Shahzad ◽  
HajraIkram Butt ◽  
Khurram Aamir ◽  
...  
Keyword(s):  
Developmental Toxicity ◽  
Pregnant Female ◽  
Female Rats
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