Minor sugar – response abnormal biological processes of the human body

Author(s):  
G. Bolotnikov
Author(s):  
Maheswara Reddy Mallu ◽  
Shaik Mohammad Anjum ◽  
Sai Sri Samyutha Katravulapalli ◽  
Sri Sai Priya Avuthu ◽  
Koteswara Reddy Gujjula ◽  
...  

Over the past decade, metabolic engineering has emerged as an active and distinct discipline characterized by its over-arching emphasis on integration. In practice, metabolic engineering is the directed improvement of cellular properties through the application of modern genetic methods. The concept of metabolic regulations deals with the varied and innumerable metabolic pathways that are present in the human body. A combination of such metabolic reactions paves the way to the proper functioning of different physiological and biological processes. Dealing with the adversities of a disease, engineering of novel metabolic pathways showcases the potential of metabolic engineering and its application in the therapeutic treatment of diseases. A proper and deeper understanding of the metabolic functions in the human body can be known from simulated yeast models. This review gives a brief understanding about the interactions between the molecular set of metabolome and its complexity.


2017 ◽  
Vol 27 (2) ◽  
pp. 331-349 ◽  
Author(s):  
Katarzyna Rżosińska ◽  
Dorota Formanowicz ◽  
Piotr Formanowicz

Abstract The complexity of many biological processes, which, thanks to the development of many fields of science, becomes for us more and more obvious, makes these processes extremely interesting for further analysis. In this paper a quantitative model of the process of macrophage differentiation, which is essential for many phenomena occurring in the human body, is proposed and analyzed. The model is expressed in the language of Petri net theory on the basis of one of the three hypotheses concerning macrophage differentiation existing in the literature. The performed analysis allowed to find an importance of individual factors in the studied phenomenon.


1997 ◽  
Vol 12 (2) ◽  
pp. 265-287 ◽  
Author(s):  
FRANS VAN POPPEL ◽  
JITSE P. VAN DIJK

As elsewhere in Europe in the middle of the nineteenth century, general dissatisfaction among Dutch doctors with their position in society and with overall levels of public health led to an active endeavour to raise their own status and to improve the level of public hygiene. For the most part these sanitary reformers or hygienists were inspired by the ‘Bodentheorie’ (literally ‘soil theory’) of the Munich hygienist Max von Pettenkofer, which postulated a specific relationship between chemical and biological processes in soil and air and in the human body, and by the Belgian statistician Adolphe Quetelet, according to whom statistics were an important means to social progress. The hygienists stressed the need for objective measures of health, including empirical research, standardization of data collection, and increased dissemination of data.Although a national system of death registration had been functioning in the Netherlands for more than thirty years, there was no national registration of causes of death. Only local registration of causes existed and these were considered insufficient and inaccurate.


2018 ◽  
Vol 11 (4) ◽  
pp. 1797-1800
Author(s):  
Alexander Poletaev

Blood (blood plasma) is a special all-pervading substance, functionally co-tuning all organs, tissues and cells of the body. To some extent blood is similar to the Ether of the ancients. In addition to performing house-keeping functions, blood is a medium for the transfer of huge amounts of information, which is continuously exchanged between all the compartments and structures of the macro-organism and its microbiome. This information is transmitted mostly in the form of chemical signals (peptides, micro-RNA, extracellular DNA, the products of the microbiome, antibodies, etc.), the totality of which controls lots of biological processes. Blood is not only a controlling, but also a reflecting environment: dynamic changes in the composition of this environment carry information about the smallest changes in the state of individual populations of cells, tissues, organs and the body as a whole. The prospects of practical using of information about the state of the organism, transmitted by blood and reflected in individual’s serum immunoreactivity profiles are analyzed.


2021 ◽  
Vol 2021 ◽  
pp. 1-13
Author(s):  
Zhi Li ◽  
Xu Wei ◽  
Shuyi Li ◽  
Jiashi Zhao ◽  
Xiang Li ◽  
...  

In recent years, researchers have discovered plant miRNA (plant xenomiR) in mammalian samples, but it is unclear whether it exists stably and participates in regulation. In this paper, a cross-border regulation model of plant miRNAs based on biological big data is constructed to study the possible cross-border regulation of plant miRNAs. Firstly, a variety of human edible plants were selected, and based on the miRNA data detected in human experimental studies, screening was performed to obtain the plant xenomiR that may stably exist in the human body. Then, we use plant and animal target gene prediction methods to obtain the mRNAs of animals and plants that may be regulated, respectively. Finally, we use GO (Gene Ontology) and the Multiple Dimensional Scaling (MDS) algorithm to analyze the biological processes regulated by plants and animals. We obtain the relationship between different biological processes and explore the regulatory commonality and individuality of plant xenomiR in plants and humans. Studies have shown that the development and metabolic functions of the human body are affected by daily eating habits. Soybeans, corn, and rice can not only affect the daily development and metabolism of the human body but also regulate biological processes such as protein modification and mitosis. This conclusion explains the reasons for the different physiological functions of the human body. This research is an important meaning for the design of small RNA drugs in Chinese herbal medicine and the treatment of human nutritional diseases.


2015 ◽  
Vol 21 (3) ◽  
pp. 838-843
Author(s):  
Fabiana Martinescu

Abstract Living organisms are in close dependence with the environment. There is also a permanent exchange of substance, energy and information between the human body and the environment, an exchange that underlies the development of all biological processes. In the normal biological processes, the essential environmental factors compete, among which we mention the air, water and food. The importance of food (lat. alimentum - aliment)consists of the intake of nutrients necessary for all life processes. The substances from food are generically described by the term “nutrient principles” or “food principles”, often being used the term “nutrients”. Among nutrients, depending on their amount in the food products and the physiological and biochemical role, there are the macronutrients (carbohydrates, lipids and protides), micronutrients (mineral compounds of biological interest and vitamins) as well as other nutrients (water, fibres, biologically-active substances).


PMLA ◽  
1996 ◽  
Vol 111 (1) ◽  
pp. 66-79 ◽  
Author(s):  
T. Hugh Crawford

In the field of medical imaging, theory, technique, and rhetoric converge to produce knowledge. Historical taboo and cultural belief in the fragility of life have protected the interior of the human body from the scientist's prying eyes; nevertheless, in the modern period (since about 1540), the production of medical knowledge has depended on the unveiling of physical detail. Recent work in the sociology of science—notably Bruno Latour's concept of the theater of proof—has questioned this epistemology. Latour argues that scientific knowledge can be produced by superimposing data that create an effect of reality. To illuminate traditional strategies for constructing convincing accounts of hidden biological processes, I examine texts by Andreas Vesalius, William Beaumont, and Wilhelm Conrad Röntgen. I then discuss an advertisement for a contemporary medical-imaging device that, by foregrounding the superimposition of diagnostic data, provides a useful counterexample to the constructed objectivity of the earlier texts.


2021 ◽  
Vol 11 ◽  
Author(s):  
Qianqian Guo ◽  
Liwen Li ◽  
Shanshan Hou ◽  
Ziqiao Yuan ◽  
Chenhui Li ◽  
...  

Iron is an essential trace element for the human body, and its deficiency or excess can induce a variety of biological processes. Plenty of evidences have shown that iron metabolism is closely related to the occurrence and development of tumors. In addition, iron plays an important role in cell death, which is very important for the development of potential strategies for tumor treatment. Here, we reviewed the latest research about iron metabolism disorders in various types of tumors, the functions and properties of iron in ferroptosis and ferritinophagy, and new opportunities for iron-based on treatment methods for tumors, providing more information regarding the prevention and treatment of tumors.


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