Two types of approaches at personification medicine development

2015 ◽  
Vol 4 (1) ◽  
pp. 81-88
Author(s):  
Филатова ◽  
O. Filatova ◽  
Хадарцева ◽  
K. Khadartseva ◽  
Еськов ◽  
...  
Keyword(s):  
Phase Space ◽  
Medical Treatment ◽  
Basic Principle ◽  
State Vector ◽  
The State ◽  
Self Organization ◽  
Human Organism ◽  
Medicine Development ◽  
State Measurement

It is evident that requirement of medical personification includes two procedures: individual (with uninterrupted procedure of human organism state measurement) diagnostics and the second part which is connected with uninterrupted control of the efficiency of medical treatment and measurements of human organism parameters. According to classic deterministic-stochastic approaches we don´t have any possibility for realization of the basic principle in medicine because every human organism has its own specific features. We conduct the diagnostics according to beha-vior of state vector of human organism in phase space of states according to every coordinates of human´s state vector and with calculation of quasiattractors. It was presented new bioinformational methods and software for calculation of quasiattractors parameters for dissolving such contradic-tions between deterministic-stochastic medicine and the use of theory of chaos self-organization where the state vector of human organism demonstrates uninterrupted movements. The practical results of such procedure are also presented according to the theory of chaos self-organization.

Analysis of Myograms Acording to the Stochastics and the Chaos Theory – Self-Organization

2015 ◽  
Vol 22 (2) ◽  
pp. 32-38
Author(s):  
Григоренко ◽  
V. Grigorenko ◽  
Горбунов ◽  
D. Gorbunov ◽  
Еськов ◽  
...  
Keyword(s):  
Phase Space ◽  
Shannon Entropy ◽  
Chaos Theory ◽  
The State ◽  
Biomechanical Analysis ◽  
Self Organization ◽  
Biological Research ◽  
Dimensional Phase Space ◽  
Low Load ◽  
Little Finger

The paper shows the feasibility of applying the method of multi-dimensional phase space as a quantitative measure for the evaluation of chaotic dynamics on the example of the muscles (flexor of the little finger). The method of multi-dimensional phase space was used. In the study and modeling of complex biological objects (complexity) there is the possibility of introducing traditional physical methods in biological research and new methods based on the chaos theory and self-organization. As a measure of the state of the neuromuscular system of the person (weak muscle tension and strong, almost the maximum force), the authors used quasi-attractors volumes of multidimensional phase space. This enables identification of the actual measurements of the parameters of the functional state with weak muscles (Fi = 5 daN) and strong (Fi = 10 daN) static stress. The authors built a timebase signal received from the electromyograph and the autocorrelation function A(t) of signal. A biomechanical analysis of the state of the system is carried out on the basis of comparison of the volume VG quasi attractor, as well as on the basis of the analysis of the Shannon entropy E. Volume of quasi attractor VG displacements under low load is slightly less than the same volume displacement VG with strong exertion of the muscles of the flexor of the little finger, exactly the same as the values of the Shannon entropy under a heavy load increases compared to the values obtained under low load the muscles.

Dynamics parameters of human psychophysiological functions under conditions of latitudinal shifts

2015 ◽  
Vol 4 (1) ◽  
pp. 95-102
Author(s):  
Буров ◽  
I. Burov ◽  
Поскина ◽  
T. Poskina ◽  
Филатов ◽  
...  
Keyword(s):  
State Vector ◽  
Open Systems ◽  
Age Groups ◽  
Fundamental Property ◽  
Ecological Factors ◽  
State Parameter ◽  
The State ◽  
Human Organism ◽  
Parameter Mismatch ◽  
The North

Adaptation is a fundamental property of organisms, which purpose is to keep quasi-attractors parameters within certain limits providing non equilibrium open systems in quasiattractor state. Parameter mismatch of functional systems, desynchronization of circadian rhythms, stability reduction of regulatory mechanisms in the conditions of the North are caused with extreme envi-ronmental parameters, chaotic oscillations of temperature and barometric modes, or socio-economic (information) changes. However, we can get the greatest expectations in this field by monitoring child population and older adults, as these are the most dangerous age groups in terms of sensitivity to ecological factors of Ugra. It is obvious that frequent vibrational motions of the state vector of the human organism do not allow it entering the stable quasi-attractor. For instance, long-term re-gimes of monotonous work, significant physical load or mental stress with short rest periods do not allow keeping the state vector of the human organism in quasi-attractors and accelerate the motion of quasi-attractor centers in the field of the mortal oscillatory rate.

Assessment of parameters state of neuromuscular cluster in the conditions of the dosed physical activity

10.12737/3860 ◽  
2014 ◽  
Vol 8 (1) ◽  
pp. 1-6
Author(s):  
Рассадина ◽  
Yu. Rassadina ◽  
Попов ◽  
Yuriy Popov ◽  
Карпин ◽  
...  
Keyword(s):  
Physical Activity ◽  
Control System ◽  
Phase Space ◽  
State Vector ◽  
Self Organization ◽  
Neuromuscular System ◽  
Two Dimensional ◽  
Practical Possibility ◽  
Dimensional Phase Space ◽  
State Vector Of System

Parameters of neuromuscular system at the unexercised and trained examinees from a position of the theory of chaos and self-organization are studied. Essential distinction between two studied groups (the trained and unexercised students) is established. Dynamics of involuntary micro-movements of extremities (fingers of hands) in a person as reaction to the dosed physical activity is shown in change of parameters of quasiattractors of characteristics of a tremor. Dynamics of increase in volumes of quasiattractors of a vector of organism state in the unexercised students is revealed. The new technique of research of a control system by movements of a person by means of the analysis of characteristics of a tremor of an extremity in the conditions of physical activity is stated. Practical possibility of application of the method of multidimensional phase spaces of involuntary micro-movement in the assessment of reaction of neuromuscular system of the person on dynamic physical activity is shown. As a measure of state of human neuromuscular system (to loading and after loading) the authors use the quasiattractors of movement of state vector of system in two-dimensional phase space of states.

Complex System Stationary Mode According to the Theory of Chaos-Self-Organization

10.12737/3329 ◽  
2014 ◽  
Vol 21 (1) ◽  
pp. 141-144
Author(s):  
Бикмухаметова ◽  
L. Bikmukhametova ◽  
Полухин ◽  
L. Polukhin ◽  
Вохмина ◽  
...  
Keyword(s):  
Phase Space ◽  
State Vector ◽  
Chaotic Dynamics ◽  
Main Idea ◽  
Self Organization ◽  
Stationary Mode ◽  
Cluster Approach ◽  
Classical Statistics ◽  
Complex Biosystems ◽  
Real Complex

Traditional biological science (biophysics, systems analyses of biosystems) stationary mode of biosystems describes according to equation dx/dt=0 for the systems state vector x=x(t)=(x1, x2,…xm)T. But real biosystems demonstrated uninterrupted chaotic dynamics when dx/dt≠0 is always uninterrupted. The authors present two types of approaches to stationary mode investigation for biosystems. The first approach is based on the compartmental-cluster theory and the second approach is based on the theory of chaos-self-organization. The last is more convenient for real biosystems description because there are pragmatic results of its use. The compartmental-cluster approach may be used for real complex biosystems and the authors present some typical examples of such theory. The stationary mode of hierarchical neural networks were illustrated according to specific audi - analyzator. It was demonstrated that short intervals of tremogram demonstrate the real difference of distribution function parameters. As a result of such experiments – the classical statistics methods don’t usefulness for investigation of postural tremor. The tremogram, cardiogram, encephalogram are the systems of third type. The main idea consists of uninterrupted chaotic movements (glimmering property) of system’s vector in phase space of state and evolution of such system’s state vector in phase space of state. The glimmering property and evolution don’t have properties which can be modeled by traditional deterministic and stochastic approaches.

Other World, Other Science, Other Models in Complexity Descreaption

10.12737/3328 ◽  
2014 ◽  
Vol 21 (1) ◽  
pp. 138-141
Author(s):  
Еськов ◽  
Valeriy Eskov ◽  
Филатова ◽  
O. Filatova
Keyword(s):  
Phase Space ◽  
State Vector ◽  
Stochastic Systems ◽  
Chaotic Behavior ◽  
Future Generation ◽  
Self Organization ◽  
Stationary Mode ◽  
Initial State ◽  
Heisenberg Uncertainty Principle ◽  
The Third

The understanding of very special systems of third type was created according to W.Weaver efforts. The new theory of chaos – self- organization was created last 40 years and was based on other understanding of stationary mode of third type of systems and its very specific chaotic behavior. The analog of the systems with physical system was discussed too. The third type of systems (opposite of deterministic and stochastic systems) was presented. It was discussed the principle distinguishes between dynamics of such system and traditional systems according to Heisenberg uncertainty principle. Traditional systems have certain and reproducible initial state of its system’s state vector and we can predict its future states. But in the third type of systems the authors have uncertain initial system state and uncertain vector states. It is a unique system which I.R. Prigogine in his famous article to the future generation determines as systems behind the science. The time for researching of such systems has come. For the modeling of biosystems, the authors propose method of quasi-attractor and define five special properties of complex systems. The main of it is connected with uninterrupted chaotic movements (glimmering property) of system’s vector in phase space of state and evolution of such system’s state vector in phase space of state. It was demonstrated that Heizenberg principle of uncertainty has special analog at theory of chaos – self organization. The botton boarder of the left side of inequality for the systems of third type the authors propose the value of quasiattractors, inside of it we chaos uninferrupled and chaotic movements of systems state vector. The value of quasiattractor determine like multiplication of coordinat x its speed dx/dt.

Operators and meaning of wave function

2016 ◽  
pp. 4039-4042
Author(s):  
Viliam Malcher
Keyword(s):  
Wave Function ◽  
Quantum Theory ◽  
State Vector ◽  
The State ◽  
Physical Significance ◽  
Central Problem ◽  
Quantum Mechanical ◽  
Mechanical Description ◽  
Quantum Mechanical Description ◽  
Interpretation Of Quantum Theory

The interpretation problems of quantum theory are considered. In the formalism of quantum theory the possible states of a system are described by a state vector. The state vector, which will be represented as |ψ> in Dirac notation, is the most general form of the quantum mechanical description. The central problem of the interpretation of quantum theory is to explain the physical significance of the |ψ>. In this paper we have shown that one of the best way to make of interpretation of wave function is to take the wave function as an operator.

The analysis is geometrically stable orbits of spacecraft remote sensing of the Еarth

2018 ◽  
Vol 15 (1) ◽  
pp. 12-22
Author(s):  
V. M. Artyushenko ◽  
D. Y. Vinogradov
Keyword(s):  
Remote Sensing ◽  
Gravitational Field ◽  
State Vector ◽  
Semimajor Axis ◽  
The State ◽  
Zonal Harmonics ◽  
The Earth ◽  
Conditions Of Stability

The article reviewed and analyzed the class of geometrically stable orbits (GUO). The conditions of stability in the model of the geopotential, taking into account the zonal harmonics. The sequence of calculation of the state vector of GUO in the osculating value of the argument of the latitude with the famous Ascoli-royski longitude of the ascending node, inclination and semimajor axis. The simulation is obtained the altitude profiles of SEE regarding the all-earth ellipsoid model of the gravitational field of the Earth given 7 and 32 zonal harmonics.

scholarly journals ‘Our legal responsibility…to intervene on behalf of the child’: Recognising public responsibilities for the medical treatment of children

2021 ◽  
Vol 21 (1) ◽  
pp. 19-41
Author(s):  
Jo Bridgeman
Keyword(s):  
Medical Treatment ◽  
Social Services ◽  
Local Authority ◽  
The State ◽  
Parental Authority ◽  
Best Interests ◽  
Legal Responsibility ◽  
Local Authorities ◽  
Professional Responsibilities ◽  
Seriously Ill

This article argues for recognition of public responsibilities to protect the welfare of children with respect to decisions affecting their health and medical treatment. As the quote in the title of this article, from David Plank, the Director of Social Services responsible for bringing the case of Baby Alexandra before the courts, identifies, early cases concerning children’s medical treatment were brought by local authorities to determine responsibilities to protect the welfare of children. In cases such as Re B (1981), Re J (1990) and Re W (1992), the court was asked not only to determine the child’s best interests but also to clarify the duties of the local authority, Trust, court and child’s parents to the child. The respective duties established apply to all involved in cases brought before the courts on the question of a child’s future medical treatment, whether or not the child is in the care of the state. Recent cases concerning the medical treatment of seriously ill children have involved claims of parental authority to determine the care of their child. To the contrary, this article argues that court involvement is required when parents are disagreed with the child’s treating doctors over the child’s medical treatment because of public as well as parental and professional responsibilities for the welfare of all children.

scholarly journals Combined assimilation of streamflow and snow water equivalent for mid-term ensemble streamflow forecasts in snow-dominated regions

2016 ◽  
Author(s):  
Jean M. Bergeron ◽  
Mélanie Trudel ◽  
Robert Leconte
Keyword(s):  
Data Assimilation ◽  
State Vector ◽  
Snow Water Equivalent ◽  
Synthetic Data ◽  
Hydrologic Model ◽  
Open Loop ◽  
The State ◽  
Wide Range ◽  
Snow Water ◽  
The Impact

Abstract. The potential of data assimilation for hydrologic predictions has been demonstrated in many research studies. Watersheds over which multiple observation types are available can potentially further benefit from data assimilation by having multiple updated states from which hydrologic predictions can be generated. However, the magnitude and time span of the impact of the assimilation of an observation varies according not only to its type, but also to the variables included in the state vector. This study examines the impact of multivariate synthetic data assimilation using the Ensemble Kalman Filter (EnKF) into the spatially distributed hydrologic model CEQUEAU for the mountainous Nechako River located in British-Columbia, Canada. Synthetic data includes daily snow cover area (SCA), daily measurements of snow water equivalent (SWE) at three different locations and daily streamflow data at the watershed outlet. Results show a large variability of the continuous rank probability skill score over a wide range of prediction horizons (days to weeks) depending on the state vector configuration and the type of observations assimilated. Overall, the variables most closely linearly linked to the observations are the ones worth considering adding to the state vector. The performance of the assimilation of basin-wide SCA, which does not have a decent proxy among potential state variables, does not surpass the open loop for any of the simulated variables. However, the assimilation of streamflow offers major improvements steadily throughout the year, but mainly over the short-term (up to 5 days) forecast horizons, while the impact of the assimilation of SWE gains more importance during the snowmelt period over the mid-term (up to 50 days) forecast horizon compared with open loop. The combined assimilation of streamflow and SWE performs better than its individual counterparts, offering improvements over all forecast horizons considered and throughout the whole year, including the critical period of snowmelt. This highlights the potential benefit of using multivariate data assimilation for streamflow predictions in snow-dominated regions.

scholarly journals Wavelet introscopy of human organism bionets

2021 ◽  
pp. 63-72
Author(s):  
Gennady M. Aldonin ◽  
◽  
Vasily V. Cherepanov ◽  
Keyword(s):  
Functional State ◽  
Human Body ◽  
Dynamic Models ◽  
Golden Ratio ◽  
The State ◽  
The Body ◽  
Human Organism ◽  
Fractal Structures ◽  
Self Similar ◽  
The Creation

In domestic and foreign practice, a great deal of experience has been accumulated in the creation of means for monitoring the functional state of the human body. The existing complexes mainly analyze the electrocardiogram, blood pressure and a number of other physiological parameters. Diagnostics is often based on formal statistical data which are not always correct due to the nonstationarity of bioprocesses and without taking into account their physical nature. An urgent task of monitoring the state of the cardiovascular system is the creation of effective algorithms for computer technologies to process biosignals based on nonlinear dynamic models of body systems since biosystems and bioprocesses have a nonlinear nature and fractal structure. The nervous and muscular systems of the heart, the vascular and bronchial systems of the human body are examples of such structures. The connection of body systems with their organization in the form of self-similar fractal structures with scaling close to the “golden ratio” makes it possible to diagnose them topically. It is possible to obtain detailed information about the state of the human body’s bio-networks for topical diagnostics on the basis of the wavelet analysis of biosignals (the so-called wavelet-introscopy). With the help of wavelet transform, it is possible to reveal the structure of biosystems and bioprocesses, as a picture of the lines of local extrema of wavelet diagrams of biosignals. Mathematical models and software for wavelet introscopy make it possible to extract additional information from biosignals about the state of biosystems. Early detection of latent forms of diseases using wavelet introscopy can shorten the cure time and reduce the consequences of disorders of the functional state of the body (FSO), and reduce the risk of disability. Taking into account the factors of organizing the body’s biosystems in the form of self-similar fractal structures with a scaling close to the “golden ratio” makes it possible to create a technique for topical diagnostics of the most important biosystems of the human body.

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