scholarly journals Effect of citric acid on the stabilization of crystalline acid carboxypeptidase from Penicillium janthinellum.

1981 ◽  
Vol 45 (1) ◽  
pp. 311-312 ◽  
Author(s):  
Sadaji YOKOYAMA ◽  
Toshinori MIYABE ◽  
Akira OOBAYASHI ◽  
Osamu TANABE ◽  
Eiji ICHISHIMA
Keyword(s):  
Citric Acid ◽  
Penicillium Janthinellum ◽  
Acid Carboxypeptidase

Action of crystalline acid carboxypeptidase from Penicillium janthinellum

1975 ◽  
Vol 397 (2) ◽  
pp. 443-448 ◽  
Author(s):  
Sadaji Yokoyama ◽  
Akira Oobayashi ◽  
Osamu Tanabe ◽  
Eiji Ichishima
Keyword(s):  
Penicillium Janthinellum ◽  
Acid Carboxypeptidase

scholarly journals Submerged Production, Purification, and Crystallization of Acid Carboxypeptidase from Penicillium janthinellum IFO-8070

1974 ◽  
Vol 28 (5) ◽  
pp. 742-747 ◽  
Author(s):  
Sadaji Yokoyama ◽  
Akira Oobayashi ◽  
Osamu Tanabe ◽  
Eiji Ichishima
Keyword(s):  
Penicillium Janthinellum ◽  
Acid Carboxypeptidase

scholarly journals Submerged Production, Purification, and Crystallization of Acid Carboxypeptidase from Penicillium janthinellum IFO-8070

1974 ◽  
Vol 28 (5) ◽  
pp. 742-747
Author(s):  
Sadaji Yokoyama ◽  
Akira Oobayashi ◽  
Osamu Tanabe ◽  
Eiji Ichishima
Keyword(s):  
Penicillium Janthinellum ◽  
Acid Carboxypeptidase

Coadministration of citric acid allows oxytetracycline dose reduction in yellowtail Seriola quinqueradiata infected with Vibrio anguillarum

2020 ◽  
Vol 140 ◽  
pp. 25-29
Author(s):  
K Akiyama ◽  
N Hirazawa ◽  
A Hatanaka
Keyword(s):  
Body Weight ◽  
Citric Acid ◽  
Effective Treatment ◽  
Dose Reduction ◽  
Vibrio Anguillarum ◽  
Enhancing Effect ◽  
Bacterial Diseases ◽  
Seriola Quinqueradiata ◽  
Poor Efficacy

Oxytetracycline (OTC) has been commonly used as an effective antibiotic against various fish bacterial diseases, including vibriosis. In this study, the absorption-enhancing effect of citric acid on oral OTC pharmacokinetics and treatment of artificial Vibrio anguillarum infection was evaluated in juvenile yellowtail Seriola quinqueradiata followed by serum OTC concentration analysis. When 25 mg kg-1 body weight (BW) OTC was administered in combination with 1250 mg kg-1 BW citric acid, the serum OTC concentration reached almost the same concentration as that of the group treated with 50 mg kg-1 BW OTC. This coadministration successfully suppressed mortality due to vibriosis similar to the group treated with 50 mg kg-1 BW OTC. Conversely, poor efficacy was observed when only 25 mg kg-1 BW OTC was administered. These results suggest that coadministration of citric acid can be beneficial in reducing the dose of OTC needed for effective treatment, and thus contributes to the goal of reduced use of this antibiotic in aquaculture.

EFFECT OF SERUM GONADOTROPHIN ON DEHYDROGENASES OF THE CITRIC ACID CYCLE IN THE OVARY OF THE RAT

1963 ◽  
Vol 42 (4) ◽  
pp. 480-484 ◽  
Author(s):  
B. Eckstein ◽  
R. Landsberg
Keyword(s):  
Citric Acid ◽  
Citric Acid Cycle ◽  
Age Groups ◽  
Succinic Dehydrogenase ◽  
Immature Rat ◽  
Acid Cycle ◽  
Immature Rats ◽  
Rat Ovary

ABSTRACT The succinic, malic and isocitric dehydrogenases in the ovary of immature and mature, normal and serum gonadotrophin injected rats were examined. The Qo2 of these enzymes were markedly enhanced in the gonadotrophin injected rats of both age groups, except in the case of succinic dehydrogenase in the ovary of the immature rats, where a slight non-significant decrease was noted. It is concluded that in the mature rat ovary, gonadotrophin administration stimulates the activity of all the examined dehydrogenases of the citric acid cycle, whereas in the immature rat ovary, at least the isocitric- and malic dehydrogenases are thus stimulated.

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