scholarly journals Safety Evaluation of the Aqueous Extract Kothala Himbutu (Salacia reticulata) Stem in the Hepatic Gene Expression Profile of Normal Mice Using DNA Microarrays

2008 ◽  
Vol 72 (12) ◽  
pp. 3075-3083 ◽  
Author(s):  
Ryanghyok IM ◽  
Hiroshi MANO ◽  
Sachie NAKATANI ◽  
Jun SHIMIZU ◽  
Masahiro WADA
Keyword(s):  
Gene Expression ◽  
Gene Expression Profile ◽  
Aqueous Extract ◽  
Expression Profile ◽  
Dna Microarrays ◽  
Safety Evaluation ◽  
Hepatic Gene Expression ◽  
Salacia Reticulata

Effect of globin digest on the liver injury and hepatic gene expression profile in galactosamine-induced liver injury in SD rats

Life Sciences ◽  
2011 ◽  
Vol 88 (15-16) ◽  
pp. 701-712 ◽  
Author(s):  
Kaori Yamamoto ◽  
Yuka Sasakawa ◽  
Fumiko Nakaoka ◽  
Mayumi Nakao ◽  
Miki Nakamura ◽  
...  
Keyword(s):  
Gene Expression ◽  
Liver Injury ◽  
Gene Expression Profile ◽  
Expression Profile ◽  
Hepatic Gene Expression ◽  
Sd Rats

Hepatic gene expression profile associated with non-alcoholic steatohepatitis protection by S-nitroso-N-acetylcysteine in ob/ob mice

2006 ◽  
Vol 45 (5) ◽  
pp. 725-733 ◽  
Author(s):  
Claudia Pinto Marques Souza de Oliveira ◽  
José Tadeu Stefano ◽  
Vicência Mara Rodrigues de Lima ◽  
Sandra Valéria de Sá ◽  
Fernanda Ibanez Simplicio ◽  
...  
Keyword(s):  
Gene Expression ◽  
Gene Expression Profile ◽  
Expression Profile ◽  
Hepatic Gene Expression ◽  
Alcoholic Steatohepatitis

scholarly journals Effect of Chronic Pioglitazone Treatment on Hepatic Gene Expression Profile in Obese C57BL/6J Mice

2015 ◽  
Vol 16 (12) ◽  
pp. 12213-12229 ◽  
Author(s):  
Chunming Jia ◽  
Yi Huan ◽  
Shuainan Liu ◽  
Shaocong Hou ◽  
Sujuan Sun ◽  
...  
Keyword(s):  
Gene Expression ◽  
Gene Expression Profile ◽  
Expression Profile ◽  
Hepatic Gene Expression ◽  
Pioglitazone Treatment

scholarly journals Effect of Chronic Valproic Acid Treatment on Hepatic Gene Expression Profile inWfs1Knockout Mouse

PPAR Research ◽  
2014 ◽  
Vol 2014 ◽  
pp. 1-11 ◽  
Author(s):  
Marite Punapart ◽  
Mall Eltermaa ◽  
Julia Oflijan ◽  
Silva Sütt ◽  
Anne Must ◽  
...  
Keyword(s):  
Gene Expression ◽  
Valproic Acid ◽  
Gene Expression Profile ◽  
Expression Profile ◽  
Expression Profiles ◽  
Peroxisome Proliferator ◽  
Hepatic Gene Expression ◽  
Wild Type ◽  
Drug Induced

Valproic acid (VPA) is a widely used anticonvulsant and mood-stabilizing drug whose use is often associated with drug-induced weight gain. Treatment with VPA has been shown to upregulateWfs1expressionin vitro. Aim of the present study was to compare the effect of chronic VPA treatment in wild type (WT) andWfs1knockout (KO) mice on hepatic gene expression profile. Wild type,Wfs1heterozygous, and homozygous mice were treated with VPA for three months (300 mg/kg i.p. daily) and gene expression profiles in liver were evaluated using Affymetrix Mouse GeneChip 1.0 ST array. We identified 42 genes affected byWfs1genotype, 10 genes regulated by VPA treatment, and 9 genes whose regulation by VPA was dependent on genotype. Among the genes that were regulated differentially by VPA depending on genotype was peroxisome proliferator-activated receptor delta (Ppard), whose expression was upregulated in response to VPA treatment in WT, but not inWfs1KO mice. Thus, regulation ofPpardby VPA is dependent onWfs1genotype.

scholarly journals Dynamics of Hepatic Gene Expression Profile in a Rat Cecal Ligation and Puncture Model

2012 ◽  
Vol 176 (2) ◽  
pp. 583-600 ◽  
Author(s):  
Qian Yang ◽  
John S.A. Mattick ◽  
Mehmet A. Orman ◽  
Tung T. Nguyen ◽  
Marianthi G. Ierapetritou ◽  
...  
Keyword(s):  
Gene Expression ◽  
Gene Expression Profile ◽  
Expression Profile ◽  
Cecal Ligation ◽  
Hepatic Gene Expression ◽  
Cecal Ligation And Puncture ◽  
Puncture Model
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