Indigofera oblongifolia regulates the hepatic gene expression profile induced by blood stage malaria

2018 ◽  
Vol 119 ◽  
pp. 170-182 ◽  
Author(s):  
Esam A. Al-Shaebi ◽  
Mohamed A. Dkhil ◽  
Saleh Al-Quraishy
Life Sciences ◽  
2011 ◽  
Vol 88 (15-16) ◽  
pp. 701-712 ◽  
Author(s):  
Kaori Yamamoto ◽  
Yuka Sasakawa ◽  
Fumiko Nakaoka ◽  
Mayumi Nakao ◽  
Miki Nakamura ◽  
...  

2006 ◽  
Vol 45 (5) ◽  
pp. 725-733 ◽  
Author(s):  
Claudia Pinto Marques Souza de Oliveira ◽  
José Tadeu Stefano ◽  
Vicência Mara Rodrigues de Lima ◽  
Sandra Valéria de Sá ◽  
Fernanda Ibanez Simplicio ◽  
...  

2015 ◽  
Vol 16 (12) ◽  
pp. 12213-12229 ◽  
Author(s):  
Chunming Jia ◽  
Yi Huan ◽  
Shuainan Liu ◽  
Shaocong Hou ◽  
Sujuan Sun ◽  
...  

PPAR Research ◽  
2014 ◽  
Vol 2014 ◽  
pp. 1-11 ◽  
Author(s):  
Marite Punapart ◽  
Mall Eltermaa ◽  
Julia Oflijan ◽  
Silva Sütt ◽  
Anne Must ◽  
...  

Valproic acid (VPA) is a widely used anticonvulsant and mood-stabilizing drug whose use is often associated with drug-induced weight gain. Treatment with VPA has been shown to upregulateWfs1expressionin vitro. Aim of the present study was to compare the effect of chronic VPA treatment in wild type (WT) andWfs1knockout (KO) mice on hepatic gene expression profile. Wild type,Wfs1heterozygous, and homozygous mice were treated with VPA for three months (300 mg/kg i.p. daily) and gene expression profiles in liver were evaluated using Affymetrix Mouse GeneChip 1.0 ST array. We identified 42 genes affected byWfs1genotype, 10 genes regulated by VPA treatment, and 9 genes whose regulation by VPA was dependent on genotype. Among the genes that were regulated differentially by VPA depending on genotype was peroxisome proliferator-activated receptor delta (Ppard), whose expression was upregulated in response to VPA treatment in WT, but not inWfs1KO mice. Thus, regulation ofPpardby VPA is dependent onWfs1genotype.


2012 ◽  
Vol 176 (2) ◽  
pp. 583-600 ◽  
Author(s):  
Qian Yang ◽  
John S.A. Mattick ◽  
Mehmet A. Orman ◽  
Tung T. Nguyen ◽  
Marianthi G. Ierapetritou ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document