Suppressive Effect of a Hot Water Extract of Adzuki Beans (Vigna angularis) on Hyperglycemia after Sucrose Loading in Mice and Diabetic Rats

2004 ◽  
Vol 68 (12) ◽  
pp. 2421-2426 ◽  
Author(s):  
Tomohiro ITOH ◽  
Nobuyuki KITA ◽  
Yuko KUROKAWA ◽  
Misato KOBAYASHI ◽  
Fumihiko HORIO ◽  
...  
Keyword(s):  
Water Extract ◽  
Suppressive Effect ◽  
Diabetic Rats ◽  
Hot Water ◽  
Vigna Angularis ◽  
Hot Water Extract ◽  
Sucrose Loading

Suppressive effect of hot water extract of wasabi (Wasabia japonica Matsum.) leaves on the differentiation of 3T3-L1 preadipocytes

2010 ◽  
Vol 118 (2) ◽  
pp. 239-244 ◽  
Author(s):  
Tetsuro Ogawa ◽  
Hiromasa Tabata ◽  
Takuya Katsube ◽  
Yukari Ohta ◽  
Yukikazu Yamasaki ◽  
...  
Keyword(s):  
Water Extract ◽  
Suppressive Effect ◽  
Hot Water ◽  
Wasabia Japonica ◽  
Hot Water Extract

The antidiabetic properties of the hot water extract of kola nut (Cola nitida (Vent.) Schott & Endl.) in type 2 diabetic rats

2019 ◽  
Vol 242 ◽  
pp. 112033 ◽  
Author(s):  
Ochuko L. Erukainure ◽  
Olakunle Sanni ◽  
Omamuyovwi M. Ijomone ◽  
Collins U. Ibeji ◽  
Chika I. Chukwuma ◽  
...  
Keyword(s):  
Water Extract ◽  
Diabetic Rats ◽  
Hot Water ◽  
Hot Water Extract ◽  
Type 2 Diabetic ◽  
Cola Nitida

scholarly journals Acute and Subchronic Toxicity Profile of a Polyherbal Drug Used in Sri Lankan Traditional Medicine

2020 ◽  
Vol 2020 ◽  
pp. 1-12
Author(s):  
Donisha Shani Niharika Keembiya Liyanagamage ◽  
Susanthi Jayasinghe ◽  
Anoja Priyadarshani Attanayake ◽  
Veranja Karunaratne
Keyword(s):  
Acute Toxicity ◽  
Glucose Concentration ◽  
Wistar Rats ◽  
Water Extract ◽  
Diabetic Rats ◽  
Acetone Extract ◽  
Hot Water ◽  
Piper Nigrum ◽  
Hot Water Extract ◽  
Acetone Extracts

A polyherbal drug composed of leaves of Murraya koenigii L. Spreng, cloves of Allium sativum L., fruits of Garcinia quaesita Pierre, and seeds of Piper nigrum L. is a popular drug which has been used by indigenous practitioners in Sri Lanka for the treatment of diabetes mellitus and dyslipidemia. The acute toxicity assessment was conducted, following a single oral dose of 0.25–2.0 g/kg in healthy rats, and rats were observed up to 14 days. The hot water extract (1.0 g/kg) and the water : acetone extract (0.5, 1.0, and 1.5 g/kg) were administered to Wistar rats for 28 days in the subchronic study. Hypoglycemic and antihyperglycemic activities (dose response studies) of cold water, hot water, and water : acetone extracts of the polyherbal mixture were evaluated at the doses of 0.5, 1.0, and 1.5 g/kg in healthy and streptozotocin-induced diabetic rats (70 mg/kg, ip), respectively. Acute toxicity study showed that the polyherbal drug did not cause any change in animals throughout the experimental period of 14 days. The administration of the hot water extract and the water : acetone extract of the polyherbal drug for 28 days did not produce changes in the selected biochemical and hematological parameters in Wistar rats (p > 0.05). The histological assessment corroborated the biochemical findings with no significant treatment-related changes in the kidney and liver. The treatment of polyherbal drug significantly lowered the serum glucose concentration compared to the diabetic control rats (p < 0.05) while it did not lead to a severe reduction of glucose concentration in healthy rats. The hot water and water : acetone extracts of the polyherbal drug showed a statistically significant improvement on total area under the glucose tolerance curve in diabetic rats (p < 0.05), reflecting dose-dependent antihyperglycemic effects of the drug. Based on the results, we conclude that the aforementioned antidiabetic polyherbal remedy is free of toxic/adverse effects at the equivalent human therapeutic dose in healthy Wistar rats and would be a safe therapeutic agent for long-term treatments.

Regulation of the differentiation of osteoblasts and osteoclasts by a hot-water extract of adzuki beans (Vigna angularis)

2014 ◽  
Vol 78 (1) ◽  
pp. 92-99 ◽  
Author(s):  
Tomohiro Itoh ◽  
Masahiro Nakamura ◽  
Hirohisa Nakamichi ◽  
Masashi Ando ◽  
Yasuyuki Tsukamasa ◽  
...  
Keyword(s):  
Water Extract ◽  
Hot Water ◽  
Vigna Angularis ◽  
Hot Water Extract

scholarly journals [Regular Paper] The Suntan Suppressive Effect by Oral Ingestion of Hot Water Extract from Salmon Nasal Cartilage:

2016 ◽  
Vol 6 (2) ◽  
pp. 138-146
Author(s):  
Masashi Goto ◽  
Yutaka Suekawa ◽  
Yukako Hanada ◽  
Ikuko Kakizaki ◽  
Kazushi Yamamoto ◽  
...  
Keyword(s):  
Water Extract ◽  
Suppressive Effect ◽  
Hot Water ◽  
Oral Ingestion ◽  
Nasal Cartilage ◽  
Regular Paper ◽  
Hot Water Extract

scholarly journals Hypoglycemic Effect of Chlorella sp. CMS-1 Hot Water Extract on Streptozotocin-Induced Diabetic Rats

2008 ◽  
Vol 18 (11) ◽  
pp. 1584-1591 ◽  
Author(s):  
Jung-Wook Kim ◽  
Jae-Young Cha ◽  
Jin-Sun Heo ◽  
Hyun-Jin Jin ◽  
Young-Su Cho
Keyword(s):  
Water Extract ◽  
Diabetic Rats ◽  
Hot Water ◽  
Hypoglycemic Effect ◽  
Chlorella Sp ◽  
Hot Water Extract

Suppressive effect of the hot-water extract of Ficus pseudopalma Blanco leaves on the postprandial increase in blood glucose level in mice

2012 ◽  
Vol 67 (4) ◽  
pp. 725-729 ◽  
Author(s):  
Reginald B. Salonga ◽  
Shinsuke Hisaka ◽  
Jasmin S. Mendoza ◽  
Yoshiaki Takaya ◽  
Masatake Niwa ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Water Extract ◽  
Suppressive Effect ◽  
Hot Water ◽  
Hot Water Extract

scholarly journals Vignoside, A Novel New Sesquiterpene Glucoside obtained from a Hot-Water Extract of Adzuki Bean (Vigna angularis)

2005 ◽  
Vol 52 (7) ◽  
pp. 319-323 ◽  
Author(s):  
Tomohiro Itoh ◽  
Yuko Itoh ◽  
Hiroshige Hibasami ◽  
Hirotaka Katsuzaki ◽  
Kunio Imai ◽  
...  
Keyword(s):  
Water Extract ◽  
Hot Water ◽  
Adzuki Bean ◽  
Vigna Angularis ◽  
Hot Water Extract

scholarly journals Isolation of a Substance Inducing Apoptosis of Cultured Human Gastric Cancer Cells from a Hot-water Extract of Adzuki (Vigna angularis)

2005 ◽  
Vol 58 (5) ◽  
pp. 281-287 ◽  
Author(s):  
Tomohiro Itoh ◽  
Yuko Itoh ◽  
Hiroshige Hibasami ◽  
Hirotaka Katsuzaki ◽  
Kunio Imai ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Cancer Cells ◽  
Water Extract ◽  
Hot Water ◽  
Human Gastric Cancer ◽  
Vigna Angularis ◽  
Gastric Cancer Cells ◽  
Hot Water Extract
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