Radical Scavenging Activity of Tea Catechins and Their Related Compounds

1999 ◽  
Vol 63 (9) ◽  
pp. 1621-1623 ◽  
Author(s):  
Fumio NANJO ◽  
Masao MORI ◽  
Keiichi GOTO ◽  
Yukihiko HARA
Keyword(s):  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Scavenging Activity ◽  
Tea Catechins ◽  
Related Compounds

Synthesis of 4-aryl-1,2,3-triazolyl appended natural coumarin-related compounds with antiproliferative and radical scavenging activities and intracellular ROS production modification

2017 ◽  
Vol 41 (15) ◽  
pp. 7531-7543 ◽  
Author(s):  
A. Bistrović ◽  
N. Stipaničev ◽  
T. Opačak-Bernardi ◽  
M. Jukić ◽  
S. Martinez ◽  
...  
Keyword(s):  
Antiproliferative Activity ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
K562 Cells ◽  
Ros Production ◽  
Scavenging Activity ◽  
Intracellular Ros ◽  
Natural Coumarin ◽  
Related Compounds

Diverse natural coumarin-based compounds linked to aryl via a 1,2,3-triazole spacer with antiproliferative activity against K562 cells, radical scavenging activity and a decrease of ROS production were provided.

scholarly journals Efficient Concentration of Functional Polyphenols Using Their Interaction with Gelatin

Foods ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 698
Author(s):  
Mizuki Hirai ◽  
Ryo Kobori ◽  
Ryo Doge ◽  
Issei Tsuji ◽  
Akiko Saito
Keyword(s):  
Green Tea ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Basic Unit ◽  
Scavenging Activity ◽  
Dpph Radical ◽  
Tea Catechins ◽  
Polyphenol Compounds ◽  
Green Tea Catechins ◽  
Tea Leaf

Among polyphenol compounds, the flavan-3-ol structure, which is the basic unit of green tea catechins and the galloyl groups contained in green tea catechins are known to exhibit various functions. In this paper, we discuss how to concentrate highly functional polyphenol compounds by exploiting the interaction between gelatin and the catechol structures. First, we confirmed the interaction between heat-stabilized gelatin and flavan-3-ol derivatives, including synthesized compounds. When green tea leaf extract containing a large amount of flavan-3-ol derivatives was incubated with gelatin, most of the polyphenol compounds it contained were adsorbed. Because the compounds adsorbed on gelatin could not be eluted, DPPH radical and ABTS radical scavenging activity tests were conducted using the as-prepared gelatin–polyphenol complex. Radical scavenging activity was observed when the compounds were adsorbed on gelatin and heating at 90 °C for 5 min did not have a significant effect on their activity. These results suggest that functional polyphenols can be efficiently concentrated using heat-stabilized gelatin and retain their functionality while adsorbed.

scholarly journals An Unusual Bisnor-clerodane Diterpenoid from Polyalthia Simiarum

2010 ◽  
Vol 5 (10) ◽  
pp. 1934578X1000501
Author(s):  
Selina Kabir ◽  
Mohammad S. Rahman ◽  
A. M. Sarwaruddin Chowdhury ◽  
Choudhury M. Hasan ◽  
Mohammad A. Rashid
Keyword(s):  
Free Radical ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Stem Bark ◽  
Free Radical Scavenging ◽  
Light Petroleum ◽  
Scavenging Activity ◽  
Nmr Studies ◽  
Clerodane Diterpenoid ◽  
Related Compounds

The stem bark of Polyalthia simiarum has yielded a new bisnor-type clerodane diterpenoid, 2-oxo-14,15-bisnor-3,11 E-kolavadien-13-one (1), and three previously known clerodane derivatives, kolavenic acid (2), 16β-hydroxycleroda-3,13(14) Z-dien-15,16-olide (3), and 16-oxocleroda-3,13(14) E-dien-15-oic acid (4). The structures of these compounds were unambiguously determined by extensive NMR studies as well as by comparison with related compounds. Till now this is the second report of the occurrence of any unusual C-18 clerodane diterpenoid from nature. The crude light petroleum extract and the purified compound 3 demonstrated moderate free radical scavenging activity with IC50 values of 21.5 and 23.5 μg/mL, respectively.

scholarly journals Free Radical Scavenging Activity of Synthetic and Naturally Occurring Polyhydroxy-, Aminohydroxynaphthazarins and Related Compounds

2018 ◽  
Vol 13 (10) ◽  
pp. 1934578X1801301 ◽  
Author(s):  
Nikita S. Polonik ◽  
Yuri E. Sabutskii ◽  
Sergey G. Polonik
Keyword(s):  
Antiradical Activity ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Scavenging Activity ◽  
Naturally Occurring ◽  
Antiradical Properties ◽  
Relationship Of ◽  
First Time ◽  
Related Compounds

Fifty natural and synthetic hydroxy-, aminohydroxynaphthazarins and related quinones were tested for their antiradical activities using 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonate) (ABTS) scavenging assay. The main features of structure-antiradical activity relationship of amino- and hydroxyquinones were determined for the first time. It was found that naphthazarins (5,8-dihydroxy-1,4-naphthoquinones) are much more active against ABTS-radical than related 1,4-naphthoquinones and 5-hydroxy-1,4-naphthoquinones. Natural aminonaphthazarins (spinamine E, echinamine A) and polyhydroxylated naphthazarins (spinazarin, echinochrome, spinochrome D and E) revealed high antiradical properties. In most cases, the presence of long chained O-alkoxy substituent in benzenoid part of naphthazarin core enhanced their antiradical activity.

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