scholarly journals Dietary Docosahexaenoic Acid Dose Not Promote Lipid Peroxidation in Rat Tissue to the Extent Expected from Peroxidizability Index of the Lipids

1998 ◽  
Vol 62 (9) ◽  
pp. 1698-1706 ◽  
Author(s):  
Kazuhiro KUBO ◽  
Morio SAITO ◽  
Tadahiro TADOKORO ◽  
Akio MAEKAWA
Keyword(s):  
Lipid Peroxidation ◽  
Docosahexaenoic Acid ◽  
Peroxidizability Index ◽  
Dietary Docosahexaenoic Acid ◽  
Rat Tissue

scholarly journals Relationship between tissue lipid peroxidation and peroxidizability index after α-linolenic, eicosapentaenoic, or docosahexaenoic acid intake in rats

2003 ◽  
Vol 89 (1) ◽  
pp. 19-28 ◽  
Author(s):  
Morio Saito ◽  
Kazuhiro Kubo
Keyword(s):  
Lipid Peroxidation ◽  
Vitamin E ◽  
Docosahexaenoic Acid ◽  
Nutritional Status ◽  
Dietary Vitamin ◽  
Tissue Lipid ◽  
Double Bonds ◽  
Adequate Level ◽  
Peroxidizability Index ◽  
Tissue Lipid Peroxidation

In a previous study, we found that the extent of dietary n-3 docosahexaenoic acid (DHA)-stimulated tissue lipid peroxidation was less than expected from the relative peroxidizability index of the total tissue lipids in rats with adequate vitamin E nutritional status. This suppression of lipid peroxidation was especially prominent in the liver. To elucidate whether this phenomenon was unique to DHA, we compared the peroxidation effects of n-3 α-linolenic acid (α-LN) and n-3 eicosapentaeonic acid (EPA) with those of DHA in rats. Either α-LN (8·6 % of total energy), EPA (8·2 %), or DHA (8·0 %) and one of two levels of dietary vitamin E (7·5 and 54 mg/kg diet) were fed to rats for 22 d. Levels of conjugated diene, chemiluminescence emission and thiobarbituric acid (TBA)-reactive substance in the liver, kidney, and testis were determined as indicators of lipid peroxidation. In rats fed the DHA diet deficient in vitamin E (7·5 m/g diet), TBA values in the liver, kidney, and testis correlated well with the tissues' relative peroxidizability indices. In rats fed the α-LN diet with an adequate level of vitamin E (54 m/g diet), a close association between relative peroxidizability indices and lipid peroxide levels was observed in all the tissues analysed. However, in rats fed either the EPA diet or the DHA diet with an adequate level of vitamin E, the extent of lipid peroxidation in each tissue was less than expected from the relative peroxidizability index. This suppression was particularly marked in the liver. We concluded that suppression of lipid peroxidation below the relative peroxidizability index was not unique to DHA, but was also seen with EPA, which has five double bonds, in rats with adequate vitamin E nutritional status, but not with α-LN, which has three double bonds.

scholarly journals Effect of Dietary Docosahexaenoic Acid Connecting Phospholipids on the Lipid Peroxidation of the Brain in Mice

2008 ◽  
Vol 54 (6) ◽  
pp. 501-506 ◽  
Author(s):  
Seiichi HIRATSUKA ◽  
Kenji ISHIHARA ◽  
Tomoko KITAGAWA ◽  
Shun WADA ◽  
Hidehiko YOKOGOSHI
Keyword(s):  
Lipid Peroxidation ◽  
Docosahexaenoic Acid ◽  
Dietary Docosahexaenoic Acid ◽  
The Brain

scholarly journals Effect of dietary docosahexaenoic acid on biosynthesis of docosahexaenoic acid from alpha-linolenic acid in young rats

2008 ◽  
Vol 49 (9) ◽  
pp. 1963-1980 ◽  
Author(s):  
James C. DeMar ◽  
Carmine DiMartino ◽  
Adam W. Baca ◽  
William Lefkowitz ◽  
Norman Salem
Keyword(s):  
Docosahexaenoic Acid ◽  
Linolenic Acid ◽  
Alpha Linolenic Acid ◽  
Young Rats ◽  
Dietary Docosahexaenoic Acid

scholarly journals Dietary Docosahexaenoic Acid and Eicosapentaenoic Acid Influence Liver Triacylglycerol and Insulin Resistance in Rats Fed a High-Fructose Diet

Marine Drugs ◽  
2015 ◽  
Vol 13 (4) ◽  
pp. 1864-1881 ◽  
Author(s):  
Gabriela Salim de Castro ◽  
Rafael Deminice ◽  
Livia Cordeiro Simões-Ambrosio ◽  
Philip C. Calder ◽  
Alceu A. Jordão ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Docosahexaenoic Acid ◽  
Eicosapentaenoic Acid ◽  
High Fructose Diet ◽  
High Fructose ◽  
Dietary Docosahexaenoic Acid

scholarly journals THE EFFECT OF VARYING LEVELS OF DIETARY DOCOSAHEXAENOIC ACID (DHA) UPON RAT PUP AUDITORY BRAINSTEM CONDUCTION TIMES (ABCTs) † 1432

1997 ◽  
Vol 41 ◽  
pp. 241-241
Author(s):  
Janet E. Stockard ◽  
Jane D. Carver ◽  
Valerie J. Benford ◽  
Robert M. Nelson ◽  
Lewis A. Barness
Keyword(s):  
Docosahexaenoic Acid ◽  
Auditory Brainstem ◽  
Dietary Docosahexaenoic Acid ◽  
Rat Pup
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