scholarly journals Isolation of a New Minor Protein (Ovofactor-1), Which Has a Cell Growth Promoting Activity, from Hen’s Egg White by Heparin Affinity Chromatography

1995 ◽  
Vol 59 (10) ◽  
pp. 1946-1948 ◽  
Author(s):  
Tadashi Nakamura ◽  
Tadao Saito ◽  
Haruki Kitazawa ◽  
Sanae Takeuchi ◽  
Takatoshi Itoh
Keyword(s):  
Cell Growth ◽  
Affinity Chromatography ◽  
Egg White ◽  
Hen’S Egg ◽  
A Cell ◽  
Minor Protein ◽  
Growth Promoting ◽  
Heparin Affinity

Release of a cell growth promoting factor from human platelets

1976 ◽  
Vol 8 (4) ◽  
pp. 493-500 ◽  
Author(s):  
Christer Busch ◽  
Åke Wasteson ◽  
Bengt Westermark
Keyword(s):  
Cell Growth ◽  
Human Platelets ◽  
A Cell ◽  
Growth Promoting

Presence of Cell Growth Promoting Peptides in Chicken Egg White Extract

1989 ◽  
Vol 53 (5) ◽  
pp. 1291-1295
Author(s):  
Norihiro Azuma ◽  
Hiroaki Mori ◽  
Shuichi Kaminogawa ◽  
Kunio Yamauchi
Keyword(s):  
Cell Growth ◽  
Egg White ◽  
Chicken Egg ◽  
Growth Promoting

scholarly journals Presence of cell growth promoting peptides in chicken egg white extract.

1989 ◽  
Vol 53 (5) ◽  
pp. 1291-1295 ◽  
Author(s):  
Norihiro AZUMA ◽  
Hiroaki MORI ◽  
Shuichi KAMINOGAWA ◽  
Kunio YAMAUCHI
Keyword(s):  
Cell Growth ◽  
Egg White ◽  
Chicken Egg ◽  
Growth Promoting

Fisetin Attenuates AKT Associated Growth Promoting Events in AflatoxinB1 Induced Hepatocellular Carcinoma

2019 ◽  
Vol 18 (13) ◽  
pp. 1885-1891 ◽  
Author(s):  
Brajesh K. Maurya ◽  
Surendra K. Trigun
Keyword(s):  
Hepatocellular Carcinoma ◽  
Cell Growth ◽  
Glycogen Synthase ◽  
Nuclear Antigen ◽  
Akt Phosphorylation ◽  
Dependent Cell ◽  
A Cell ◽  
Growth Promoting ◽  
Phosphatase And Tensin Homologue

Background: Recently, we have reported that Fisetin, a natural flavonol, is able to regress Aflatoxin- B1 (AFB1) induced hepatocellular carcinoma (HCC) by suppressing reactive oxygen species (ROS) led proinflammatory factors in rats. In the current study, we aimed to delineate whether Fisetin does so by modulating the cell growth promoting signaling cascade in HCC. The reciprocal interplay of 3-phosphoinositol kinase (PI3K) vs phosphatase and tensin homologue deleted on chromosome 10 (PTEN) displays Akt, a protein kinase B, to get phosphorylated at Thr308 by a 3-phosphoinositol dependent kinase 1 (PDK1). This commits cells of neoplastic niche to undergo rapid proliferation by p-Aktthr308 dependent phosphorylation of glycogen synthase kinase 3β (GSK3β) at Ser 9 position. Method: In this study, the effect of in vivo treatment of 20 mg/kg b.w. Fisetin on relative profile of all these factors were studied in the liver from the HCC rats induced by two doses of 1mg/kg b.w. AFB1 i.p. Result: As compared to the untreated HCC liver, liver from Fisetin treated HCC group rats showed a significant decline in the activity and level of p-Aktthr308 which was consistent with a similar decline in PDK1 level. Concordantly, the level of p-GSK3βSer 9 was also found to be declined significantly in those Fisetin-treated HCC livers. Conclusion: A concomitant decline in immunohistochemically detected number of the proliferating cell nuclear antigen (PCNA), a cell proliferation marker, in the HCC liver, further confirmed anti-cell proliferative role of Fisetin during HCC growth in vivo. These findings suggest that Fisetin is able to suppress Akt dependent cell growth signaling mechanisms in HCC mainly by down regulating PDK1 dependent Akt phosphorylation.

scholarly journals Integrative Genomics RevealedRAI3Is a Cell Growth-promoting Gene and a Novel P53 Transcriptional Target

2005 ◽  
Vol 280 (13) ◽  
pp. 12935-12943 ◽  
Author(s):  
Qun Wu ◽  
Wei Ding ◽  
Asra Mirza ◽  
Tish Van Arsdale ◽  
Iris Wei ◽  
...  
Keyword(s):  
Cell Growth ◽  
Integrative Genomics ◽  
A Cell ◽  
Growth Promoting ◽  
Transcriptional Target

Separation of minor protein components from whey protein isolates by heparin affinity chromatography

2008 ◽  
Vol 18 (10-11) ◽  
pp. 1043-1050 ◽  
Author(s):  
Wassef Ben Ounis ◽  
Sylvie F. Gauthier ◽  
Sylvie L. Turgeon ◽  
Samira Roufik ◽  
Yves Pouliot
Keyword(s):  
Affinity Chromatography ◽  
Whey Protein ◽  
Protein Isolates ◽  
Minor Protein ◽  
Protein Components ◽  
Whey Protein Isolates ◽  
Heparin Affinity
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