Trials for safety assessments of the transgenic rice expressing T cell epitopes derived from Japanese cedar pollen allergens—Environmental assessments for biodiversity and the large scale cultivation under the isolated field—

Sakiko Hirose; Hidenori Takagi; Taiji Kawakatsu; Yuhya Wakasa; Eiji Domon; Yuji Endo; Ken-ichi Muraoka; Kazuo Hirai; Tomonari Watanabe; Makoto Hattori; Ken Tateishi; Fumio Takaiwa

doi:10.1270/jsbbr.10.23

Trials for safety assessments of the transgenic rice expressing T cell epitopes derived from Japanese cedar pollen allergens—Environmental assessments for biodiversity and the large scale cultivation under the isolated field—

Breeding Research ◽

10.1270/jsbbr.10.23 ◽

2008 ◽

Vol 10 (1) ◽

pp. 23-30

Author(s):

Sakiko Hirose ◽

Hidenori Takagi ◽

Taiji Kawakatsu ◽

Yuhya Wakasa ◽

Eiji Domon ◽

...

Keyword(s):

T Cell ◽

Large Scale ◽

Japanese Cedar ◽

T Cell Epitopes ◽

Pollen Allergens ◽

Environmental Assessments ◽

Japanese Cedar Pollen ◽

Safety Assessments ◽

Large Scale Cultivation ◽

Cedar Pollen

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Biochemical Safety Evaluation of Transgenic Rice Seeds Expressing T Cell Epitopes of Japanese Cedar Pollen Allergens

Journal of Agricultural and Food Chemistry ◽

10.1021/jf061848v ◽

2006 ◽

Vol 54 (26) ◽

pp. 9901-9905 ◽

Cited By ~ 36

Author(s):

Hidenori Takagi ◽

Sakiko Hirose ◽

Hiroshi Yasuda ◽

Fumio Takaiwa

Keyword(s):

T Cell ◽

Transgenic Rice ◽

Safety Evaluation ◽

Japanese Cedar ◽

T Cell Epitopes ◽

Pollen Allergens ◽

Japanese Cedar Pollen ◽

Rice Seeds ◽

Cedar Pollen

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Immunological and Symptomatic Effects of Oral Intake of Transgenic Rice Containing 7 Linked Major T-Cell Epitopes from Japanese Cedar Pollen Allergens

International Archives of Allergy and Immunology ◽

10.1159/000509996 ◽

2020 ◽

pp. 1-11

Author(s):

Tomonori Endo ◽

Daiya Asaka ◽

Tsuguhisa Nakayama ◽

Shota Saito ◽

Hiroki Kodama ◽

...

Keyword(s):

T Cell ◽

Transgenic Rice ◽

Oral Intake ◽

Japanese Cedar ◽

T Cell Epitopes ◽

Pollen Allergens ◽

Japanese Cedar Pollen ◽

Cedar Pollen

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Production of Therapeutic Proteins Composed of Seven Dominant Human T Cell Epitopes Derived from the Japanese Cedar Pollen Allergens

Basic and Applied Aspects ◽

10.1007/978-90-481-3892-0_34 ◽

2010 ◽

pp. 209-214

Author(s):

Yoshinori Kawabe ◽

Yoshifumi Hayashida ◽

Kensaku Numata ◽

Akira Hishigae ◽

Akira Ito ◽

...

Keyword(s):

T Cell ◽

Therapeutic Proteins ◽

Japanese Cedar ◽

T Cell Epitopes ◽

Pollen Allergens ◽

Human T Cell ◽

Japanese Cedar Pollen ◽

Cedar Pollen

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Evaluation of basophil activation caused by transgenic rice seeds expressing whole T cell epitopes of the major Japanese cedar pollen allergens

Clinical and Translational Allergy ◽

10.1186/s13601-019-0249-8 ◽

2019 ◽

Vol 9 (1) ◽

Cited By ~ 4

Author(s):

Shinya Takaishi ◽

Saburo Saito ◽

Minori Kamada ◽

Nobuyoshi Otori ◽

Hiromi Kojima ◽

...

Keyword(s):

T Cell ◽

Transgenic Rice ◽

Japanese Cedar ◽

Basophil Activation ◽

T Cell Epitopes ◽

Pollen Allergens ◽

Japanese Cedar Pollen ◽

Rice Seeds ◽

Cedar Pollen

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Nisin-induced expression of recombinant T cell epitopes of major Japanese cedar pollen allergens in Lactococcus lactis

Applied Microbiology and Biotechnology ◽

10.1007/s00253-017-8579-8 ◽

2017 ◽

Vol 102 (1) ◽

pp. 261-268 ◽

Cited By ~ 6

Author(s):

Vinh Van Hoang ◽

Takahumi Ochi ◽

Kentaro Kurata ◽

Yutaka Arita ◽

Yusuke Ogasahara ◽

...

Keyword(s):

T Cell ◽

Lactococcus Lactis ◽

Japanese Cedar ◽

T Cell Epitopes ◽

Pollen Allergens ◽

Induced Expression ◽

Japanese Cedar Pollen ◽

Cedar Pollen

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Preclinical evaluation of an immunotherapeutic peptide comprising 7 T-cell determinants of Cry j 1 and Cry j 2, the major Japanese cedar pollen allergens

Journal of Allergy and Clinical Immunology ◽

10.1067/mai.2001.115481 ◽

2001 ◽

Vol 108 (1) ◽

pp. 94-100 ◽

Cited By ~ 56

Author(s):

Kazuki Hirahara ◽

Toru Tatsuta ◽

Toshiro Takatori ◽

Masahiko Ohtsuki ◽

Hideyo Kirinaka ◽

...

Keyword(s):

T Cell ◽

Japanese Cedar ◽

Pollen Allergens ◽

Preclinical Evaluation ◽

Japanese Cedar Pollen ◽

Cedar Pollen ◽

Cry J 2

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26-Week Oral Safety Study in Macaques for Transgenic Rice Containing Major Human T-Cell Epitope Peptides from Japanese Cedar Pollen Allergens

Journal of Agricultural and Food Chemistry ◽

10.1021/jf900371u ◽

2009 ◽

Vol 57 (12) ◽

pp. 5633-5638 ◽

Cited By ~ 15

Author(s):

Eiji Domon ◽

Hidenori Takagi ◽

Sakiko Hirose ◽

Koichi Sugita ◽

Saori Kasahara ◽

...

Keyword(s):

T Cell ◽

Transgenic Rice ◽

Cell Epitope ◽

Japanese Cedar ◽

T Cell Epitope ◽

Pollen Allergens ◽

Safety Study ◽

Human T Cell ◽

Japanese Cedar Pollen ◽

Cedar Pollen

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Expression of recombinant T-cell epitopes of major Japanese cedar pollen allergens fused with cholera toxin B subunit in Escherichia coli

Protein Expression and Purification ◽

10.1016/j.pep.2015.02.001 ◽

2015 ◽

Vol 109 ◽

pp. 62-69 ◽

Cited By ~ 4

Author(s):

Vinh Van Hoang ◽

Yanshuang Zou ◽

Kentaro Kurata ◽

Keiichi Enomoto

Keyword(s):

Escherichia Coli ◽

Japanese Cedar ◽

Cholera Toxin B Subunit ◽

T Cell Epitopes ◽

Pollen Allergens ◽

Toxin B ◽

Cholera Toxin B ◽

B Subunit ◽

Japanese Cedar Pollen ◽

Cedar Pollen

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Identification of human T cell epitopes in Japanese cypress pollen allergen, Cha o 1, elucidates the intrinsic mechanism of cross-allergenicity between Cha o 1 and Cry j 1, the major allergen of Japanese cedar pollen, at the T cell level

Clinical & Experimental Allergy ◽

10.1111/j.1365-2222.2005.02221.x ◽

2005 ◽

Vol 35 (5) ◽

pp. 664-671 ◽

Cited By ~ 32

Author(s):

T. Sone ◽

K. Dairiki ◽

K. Morikubo ◽

K. Shimizu ◽

H. Tsunoo ◽

...

Keyword(s):

T Cell ◽

Japanese Cedar ◽

Major Allergen ◽

T Cell Epitopes ◽

Cell Level ◽

Japanese Cypress ◽

Human T Cell ◽

Intrinsic Mechanism ◽

Japanese Cedar Pollen ◽

Cedar Pollen

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T‐cell activation by transgenic rice seeds expressing the genetically modified Japanese cedar pollen allergens

Immunology ◽

10.1111/imm.13097 ◽

2019 ◽

Vol 158 (2) ◽

pp. 94-103

Author(s):

Shinya Takaishi ◽

Saburo Saito ◽

Tomonori Endo ◽

Daiya Asaka ◽

Yuhya Wakasa ◽

...

Keyword(s):

T Cell ◽

Transgenic Rice ◽

T Cell Activation ◽

Cell Activation ◽

Genetically Modified ◽

Japanese Cedar ◽

Pollen Allergens ◽

Japanese Cedar Pollen ◽

Rice Seeds ◽

Cedar Pollen

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