scholarly journals HISTOCHEMICAL STUDY ON THE INTRAVITAL REDUCTION POTENCY OF COENZYME Q IN THE RESPIRATORY CHAIN OF THE HAIR CELLS OF THE SPIRAL ORGAN IN NORMAL GUINEA PIGS AND ITS ALTERATION IN ACUTE STARVATION AND VITAMIN B1 DEFICIENCY

1973 ◽  
Vol 6 (4) ◽  
pp. 233-247 ◽  
Author(s):  
MASATOYO AKIYOSHI ◽  
KIICHI SATO ◽  
HOZUMI NAKADA
Keyword(s):  
Respiratory Chain ◽  
Hair Cells ◽  
Guinea Pigs ◽  
Histochemical Study ◽  
Coenzyme Q ◽  
Vitamin B1 ◽  
Acute Starvation ◽  
Vitamin B1 Deficiency

Comparative studies on vitamin B1 deficiency in whole blood of chronically haemodialysed patients: chromatographic, fluorimetric and PCA study

2021 ◽  
pp. 122880
Author(s):  
Paweł B. Rudnicki-Velasquez ◽  
Hanna Storoniak ◽  
Karolina Jagiełło ◽  
Joanna Kreczko–Kurzawa ◽  
Magdalena Jankowska ◽  
...  
Keyword(s):  
Whole Blood ◽  
Comparative Studies ◽  
Vitamin B1 ◽  
Vitamin B1 Deficiency

ADULT SCURVY ASSOCIATED WITH VITAMIN-B1 DEFICIENCY

The Lancet ◽  
1938 ◽  
Vol 231 (5990) ◽  
pp. 1385-1387 ◽  
Author(s):  
J. Bruce Young
Keyword(s):  
Vitamin B1 ◽  
Vitamin B1 Deficiency

scholarly journals Wernicke’s encephalopathy: An uncommon complication from hyperemesis gravidarum

2019 ◽  
Vol 13 (4) ◽  
pp. 198-200
Author(s):  
Roshan Shah ◽  
Isabelle Malhamé ◽  
Mariam Fayek ◽  
Alisa Merolli ◽  
Niharika Mehta
Keyword(s):  
Hyperemesis Gravidarum ◽  
Vitamin B1 ◽  
Wernicke’S Encephalopathy ◽  
Nutritional Deficiencies ◽  
Wernicke's Encephalopathy ◽  
Gait Ataxia ◽  
Severe Nausea ◽  
Neurologic Manifestation ◽  
Vitamin B1 Deficiency ◽  
Uncommon Complication

Hyperemesis gravidarum is a complication of pregnancy associated with severe nausea and vomiting that can lead to fluid-electrolyte imbalances and nutritional deficiencies. Wernicke’s encephalopathy is a neurologic manifestation of acute thiamine (vitamin B1) deficiency. We describe a case of hyperemesis gravidarum presenting with gait ataxia and nystagmus which led to a diagnosis of Wernicke’s encephalopathy.

scholarly journals Synaptic migration and reorganization after noise exposure suggests regeneration in a mature mammalian cochlea

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Tyler T. Hickman ◽  
Ken Hashimoto ◽  
Leslie D. Liberman ◽  
M. Charles Liberman
Keyword(s):  
Hair Cell ◽  
Hair Cells ◽  
Auditory Nerve ◽  
Guinea Pigs ◽  
Noise Exposure ◽  
Recovery Period ◽  
Nerve Fibers ◽  
Neural Regeneration ◽  
Adult Mice ◽  
Synaptic Markers

AbstractOverexposure to intense noise can destroy the synapses between auditory nerve fibers and their hair cell targets without destroying the hair cells themselves. In adult mice, this synaptopathy is immediate and largely irreversible, whereas, in guinea pigs, counts of immunostained synaptic puncta can recover with increasing post-exposure survival. Here, we asked whether this recovery simply reflects changes in synaptic immunostaining, or whether there is actual retraction and extension of neurites and/or synaptogenesis. Analysis of the numbers, sizes and spatial distribution of pre- and post-synaptic markers on cochlear inner hair cells, in guinea pigs surviving from 1 day to 6 months after a synaptopathic exposure, shows dramatic synaptic re-organization during the recovery period in which synapse counts recover from 16 to 91% of normal in the most affected regions. Synaptic puncta move all over the hair cell membrane during recovery, translocating far from their normal positions at the basolateral pole, and auditory-nerve terminals extend towards the hair cell’s apical end to re-establish contact with them. These observations provide stronger evidence for spontaneous neural regeneration in a mature mammalian cochlea than can be inferred from synaptic counts alone.

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