scholarly journals Diagnostic Accuracy of Intraoperative Intact Parathyroid Hormone Monitoring for Surgical Outcomes of Secondary Hyperparathyroidism

2021 ◽  
Vol 27 ◽  
Author(s):  
Yuanyuan Chen ◽  
Bin Liang ◽  
Xiaofeng Dong ◽  
Tao Huang ◽  
Tian-qi Liu
Keyword(s):  
Parathyroid Hormone ◽  
Diagnostic Accuracy ◽  
Secondary Hyperparathyroidism ◽  
Surgical Outcomes ◽  
Intact Parathyroid Hormone ◽  
Parathyroid Hormone Monitoring

Intra-operative parathyroid hormone monitoring in secondary hyperparathyroidism: is it useful?

2006 ◽  
Vol 31 (3) ◽  
pp. 198-203 ◽  
Author(s):  
A. Roshan ◽  
B. Kamath ◽  
S. Roberts ◽  
S.L. Atkin ◽  
R.J.A. England
Keyword(s):  
Parathyroid Hormone ◽  
Secondary Hyperparathyroidism ◽  
Parathyroid Hormone Monitoring

scholarly journals Pre-operative Localisation of the Parathyroid Glands in Secondary Hyperparathyroidism: A Retrospective Cohort Study

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Takahisa Hiramitsu ◽  
Toshihide Tomosugi ◽  
Manabu Okada ◽  
Kenta Futamura ◽  
Makoto Tsujita ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Cohort Study ◽  
Parathyroid Hormone ◽  
Secondary Hyperparathyroidism ◽  
Retrospective Cohort ◽  
Parathyroid Glands ◽  
Imaging Modalities ◽  
Intact Parathyroid Hormone ◽  
Intact Pth ◽  
Persistent Hyperparathyroidism

Abstract Complete parathyroidectomy (PTx) is essential during total PTx for secondary hyperparathyroidism (SHPT) to prevent recurrent and persistent hyperparathyroidism. Pre-operative imaging evaluations, including computed tomography (CT), ultrasonography (US), and Tc-99m sestamibi (MIBI) scans, are commonly performed. Between June 2009 and January 2016, 291 patients underwent PTx for SHPT after pre-operative evaluations involving CT, US, and MIBI scans, and the diagnostic accuracies of these imaging modalities for identifying the parathyroid glands were evaluated in 177 patients whose intact parathyroid hormone (PTH) levels were <9 pg/mL after the initial PTx. Additional PTx procedures were performed on 7 of 114 patients whose intact PTH levels were >9 ng/mL after PTx, and the diagnostic validities of the imaging modalities for the remnant parathyroid glands were evaluated. A combination of CT, US, and MIBI scans achieved the highest diagnostic accuracy (75%) for locating bilateral upper and lower parathyroid glands before initial PTx. The accuracies of CT, US, and MIBI scans with respect to locating remnant parathyroid glands before additional PTx were 100%, 28.6%, and 100%, respectively. A combination of CT, US, and MIBI scans is useful for initial PTx for SHPT, and CT and MIBI scans are useful imaging modalities for additional PTx procedures.

scholarly journals Can the use of intraoperative intact parathyroid hormone monitoring be abandoned in patients with hyperparathyroidism?

2013 ◽  
Vol 206 (4) ◽  
pp. 574-577 ◽  
Author(s):  
Chika Sakimura ◽  
Shigeki Minami ◽  
Naomi Hayashida ◽  
Tatsuya Uga ◽  
Naoko Inokuchi ◽  
...  
Keyword(s):  
Parathyroid Hormone ◽  
Intact Parathyroid Hormone ◽  
Parathyroid Hormone Monitoring

scholarly journals Parathyroid carcinoma survival: improvements in the era of intact parathyroid hormone monitoring?

Rare Tumors ◽  
2013 ◽  
Vol 5 (1) ◽  
pp. 44-48 ◽  
Author(s):  
Miya E. Allen ◽  
Alison Semrad ◽  
Anthony D. Yang ◽  
Steve R. Martinez
Keyword(s):  
Parathyroid Hormone ◽  
Parathyroid Carcinoma ◽  
Intact Parathyroid Hormone ◽  
Parathyroid Hormone Monitoring

Serum levels of intact parathyroid hormone in elderly patients with hip fracture living at home

1992 ◽  
Vol 126 (1) ◽  
pp. 10-12 ◽  
Author(s):  
Jan A Falch ◽  
Morten Mowé ◽  
Thomas Bøhmer ◽  
Egil Haug
Keyword(s):  
Risk Factor ◽  
Parathyroid Hormone ◽  
Hip Fracture ◽  
Elderly Patients ◽  
Secondary Hyperparathyroidism ◽  
Serum Levels ◽  
Intact Parathyroid Hormone ◽  
Control Subjects ◽  
Home Living ◽  
Age And Sex

The serum levels of intact parathyroid hormone and cholecalciferol metabolites have been measured in patients with hip fracture above 70 years of age admitted to hospital from home-living conditions and compared with serum levels in age- and sex-matched home-living control subjects. It was found that patients with hip fracture had significantly lower levels of calcidiol (29.7±15.9 vs 46.0±27.8 nmol/l) and calcitriol (63.6±25.0 vs 91.1±39.5 pmol/l) with no difference in serum levels of intact parathyroid hormone (47.2±2.1 vs 5.3±3.3 pmol/l). The data suggest that secondary hyperparathyroidism is not an important risk factor in our population of patients with hip fracture.

scholarly journals Changes in 3-month mineral and bone disorder patterns were associated with all-cause mortality in prevalent hemodialysis patients with secondary hyperparathyroidism

2020 ◽  
Author(s):  
Chihiro Kato ◽  
Naohiko Fujii ◽  
Chisato Miyakoshi ◽  
Shinji Asada ◽  
Yoshihiro Onishi ◽  
...  
Keyword(s):  
Parathyroid Hormone ◽  
Secondary Hyperparathyroidism ◽  
Hemodialysis Patients ◽  
Lower Mortality ◽  
Intact Parathyroid Hormone ◽  
Mineral And Bone Disorder ◽  
High Category ◽  
Bone Disorder ◽  
All Cause Mortality ◽  
Changing Patterns

Abstract Background. There is limited evidence on the association between short-term changes in mineral and bone disorder parameters and survival in maintenance hemodialysis patients. Methods. We investigated the association between changing patterns of phosphorus, calcium and intact parathyroid hormone levels and all-cause mortality in hemodialysis patients with secondary hyperparathyroidism. Each parameter was divided into three categories (low [L], middle [M] and high [H]), and the changing patterns between two consecutive visits at 3-month intervals were categorized into nine groups (e.g., L-L and M-H). The middle category was defined as 4.0-7.0 mg/dL for phosphorous, 8.5-9.5 mg/dL for calcium and 200-500 pg/mL for intact parathyroid hormone. Adjusted incidence rates and rate ratios were analyzed by weighted Poisson regression models accounting for time-dependent exposures. Results. For phosphorus, shifts from low/high to middle category (L-M/H-M) were associated with a lower mortality compared with the L-L and H-H groups, whereas shifts from middle to low/high category (M-L/M-H) were associated with a higher mortality compared with the M-M group. For calcium, shifts from low/middle to high category (L-H/M-H) were associated with a higher mortality compared with the L-L and M-M groups, whereas shifts from high to middle category (H-M) were associated with a lower mortality compared with the H-H group. For intact parathyroid hormone, shifts from low to middle category (L-M) were associated with a lower mortality compared with the L-L group. Conclusions. Changes in the 3-month patterns of phosphorus and calcium toward the middle category were associated with lower mortality. Our study also suggests the importance of avoiding hypercalcemia.

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