scholarly journals Expression of Heat Shock Protein-27 (Hsp27) and P38MAPK in Esophageal Squamous Cell Carcinoma

2017 ◽  
Vol 23 ◽  
pp. 5246-5253 ◽  
Author(s):  
Yan Zhang ◽  
Zhiyin Feng ◽  
Weina Wang ◽  
Juanjuan Dong ◽  
Xiaojin Gong ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Heat Shock ◽  
Esophageal Squamous Cell Carcinoma ◽  
Heat Shock Protein ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Heat Shock Protein 27

Heat shock protein 27 and p16 immunohistochemistry in cervical intraepithelial neoplasia and squamous cell carcinoma

Human Cell ◽  
2012 ◽  
Vol 25 (1) ◽  
pp. 24-28 ◽  
Author(s):  
Akiko Tozawa-Ono ◽  
Ayako Yoshida ◽  
Noriyuki Yokomachi ◽  
Rumiko Handa ◽  
Hirotaka Koizumi ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Heat Shock ◽  
Heat Shock Protein ◽  
Cell Carcinoma ◽  
Cervical Intraepithelial Neoplasia ◽  
Squamous Cell ◽  
Intraepithelial Neoplasia ◽  
Heat Shock Protein 27 ◽  
P16 Immunohistochemistry

scholarly journals Correlation between Clinicopathology and Expression of Heat Shock Protein 72 and Glycoprotein 96 in Human Esophageal Squamous Cell Carcinoma

2010 ◽  
Vol 2010 ◽  
pp. 1-8 ◽  
Author(s):  
Xiaoping Wang ◽  
Qiaoxia Wang ◽  
Huanping Lin
Keyword(s):  
Squamous Cell Carcinoma ◽  
Heat Shock ◽  
Esophageal Squamous Cell Carcinoma ◽  
Heat Shock Protein ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Squamous Cell Carcinomas ◽  
Heat Shock Protein 72 ◽  
Primary Tumors ◽  
Esophageal Squamous Cell Carcinomas

Heat shock protein 72 (HSP72) and glycoprotein 96 (gp96) are highly expressed in cancer tissues. Recent studies indicate the possible roles of HSP72 and gp96 in the development and progression of gastrointestinal carcinomas but detailed information is still ambiguous. We investigated the correlation between clinicopathology and expression of HSP72 and gp96 in human esophageal squamous cell carcinoma. The expression of HSP72 and gp96 was studied in 120 human esophageal squamous cell carcinomas with or without metastasis as well as in mucous membrane adjacent to cancers by way of immunohistochemistry. HSP72 immunoreactivities were detected in 112 of 120 primary tumors (93.3%) and in 30 of 120 mucous membranes adjacent to cancers (25.0%). Gp96 detected in esophageal squamous cell carcinoma and inmucous membrane adjacent to cancer was 85.0% and 20.0%, respectively. Both HSP72 and gp96 stained in cytoplasm. HSP72 and gp96 expression in esophageal squamous cell carcinomas withmetastasis was significantly higher than those with nonmetastasis (P<.05). The results indicate that there exists a significant correlation between the expression of HSP72 and gp96 and the progression of esophageal squamous cell carcinomas. HSP72 and gp96 expression were significantly associated with the presence of tumor infiltration, lymph node, and remote metastasis.

Expression of heat shock protein 70 in grossly resected esophageal squamous cell carcinoma

2002 ◽  
Vol 74 (1) ◽  
pp. 222-226 ◽  
Author(s):  
Tsuyoshi Noguchi ◽  
Shinsuke Takeno ◽  
Tomotaka Shibata ◽  
Yuzo Uchida ◽  
Shigeo Yokoyama ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Heat Shock ◽  
Esophageal Squamous Cell Carcinoma ◽  
Heat Shock Protein ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Heat Shock Protein 70

scholarly journals Dysregulation of heat shock protein 27 expression in oral tongue squamous cell carcinoma

BMC Cancer ◽  
2009 ◽  
Vol 9 (1) ◽  
Author(s):  
Anxun Wang ◽  
Xiqiang Liu ◽  
Shihu Sheng ◽  
Hui Ye ◽  
Tingsheng Peng ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Heat Shock ◽  
Heat Shock Protein ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Heat Shock Protein 27 ◽  
Tongue Squamous Cell Carcinoma ◽  
Oral Tongue

scholarly journals Heat Shock Protein 27 as a New Therapeutic Target for Radiation Sensitization of Head and Neck Squamous Cell Carcinoma

2009 ◽  
Vol 17 (8) ◽  
pp. 1387-1394 ◽  
Author(s):  
Elie Hadchity ◽  
Marie-Thérèse Aloy ◽  
Christian Paulin ◽  
Emma Armandy ◽  
Emmanuel Watkin ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Heat Shock ◽  
Heat Shock Protein ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Therapeutic Target ◽  
Heat Shock Protein 27 ◽  
Neck Squamous Cell Carcinoma ◽  
Radiation Sensitization
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