scholarly journals Feasibility of Diffusion Tensor Imaging for Assessing Functional Recovery in Rats with Olfactory Ensheathing Cell Transplantation After Contusive Spinal Cord Injury (SCI)

2017 ◽  
Vol 23 ◽  
pp. 2961-2971
Author(s):  
Mengchao Gu ◽  
Zhengchao Gao ◽  
Xiaohui Li ◽  
Feng Zhao ◽  
Lei Guo ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Diffusion Tensor Imaging ◽  
Cell Transplantation ◽  
Functional Recovery ◽  
Diffusion Tensor ◽  
Olfactory Ensheathing Cell ◽  
Cord Injury ◽  
Contusive Spinal Cord Injury

scholarly journals Serial Diffusion Tensor Imaging In Vivo Predicts Long-Term Functional Recovery and Histopathology in Rats following Different Severities of Spinal Cord Injury

2016 ◽  
Vol 33 (10) ◽  
pp. 917-928 ◽  
Author(s):  
Samir P. Patel ◽  
Taylor D. Smith ◽  
Jenna L. VanRooyen ◽  
David Powell ◽  
David H. Cox ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Diffusion Tensor Imaging ◽  
Functional Recovery ◽  
Diffusion Tensor ◽  
Cord Injury

scholarly journals Noninvasive diffusion tensor imaging of evolving white matter pathology in a mouse model of acute spinal cord injury

2007 ◽  
Vol 58 (2) ◽  
pp. 253-260 ◽  
Author(s):  
Joong Hee Kim ◽  
David N. Loy ◽  
Hsiao-Fang Liang ◽  
Kathryn Trinkaus ◽  
Robert E. Schmidt ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Diffusion Tensor Imaging ◽  
White Matter ◽  
Mouse Model ◽  
Diffusion Tensor ◽  
Acute Spinal Cord Injury ◽  
Cord Injury ◽  
White Matter Pathology

scholarly journals Comparison of intramedullary transplantation of olfactory ensheathing cell for patients with chronic complete spinal cord injury worldwide

2018 ◽  
Vol 1 (1) ◽  
pp. 146-151 ◽  
Author(s):  
Lin Chen ◽  
Yuqi Zhang ◽  
Xijing He ◽  
Saberi Hooshang
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Cell Transplantation ◽  
Clinical Results ◽  
Postoperative Management ◽  
Olfactory Ensheathing Cells ◽  
Olfactory Ensheathing Cell ◽  
Advantages And Disadvantages ◽  
Cord Injury ◽  
Ensheathing Cells

Objectives:Traumatic spinal cord injury (tSCI) remains a major clinical challenge. Cell transplantation brings a glimmer of light, among them olfactory ensheathing cells (OECs) have shown some neurorestorative effect. Due to the results of each group lack basic consistency, many technical details are believed to affect the overall outcome. We compare the clinical outcome of intramedullary transplant of olfactory ensheathing cells for patients with spinal cord injury at multi-centers worldwide, and to explore the potential standardized transplantation that suits for the clinical requirements.Methods:Here, we used the Pubmed and CNKI databases to search online the literatures published in the last 20 years for the clinical studies/trials of OECs for chronic spinal cord injury in the representative clinical center. The results of these representative clinical treatment centers were searched and analyzed. The parameters which may affect the effect including the concentration of cells, the total number of cells, the choice of incision, the site of transplantation, the number of transplantation sites, the advantages and disadvantages of transplantation equipment, and postoperative management, were compared carefully to clarify its impact on the clinical results.Results:In these literatures, 2 Chinese centers, 1 Australian center and 1 European center were selected for intraspinal transplantation. The reason of different results may be due to the excessive injection times and/or the excessive total injection volume.Conclusions:Cell implant to the spinal cord parenchyma is effective for restoring neurological functions, but improper procedures may lead to ineffective results. Concise surgery appears to be more suitable for clinical application than ostensibly precise and complex injection procedures. Sufficient rehabilitation training is surely necessary for the integration of motor recovery after cell transplantation.

scholarly journals Diffusion Tensor Imaging in Diagnosis of Post-Traumatic Syringomyelia in Spinal Cord Injury in Rats

2018 ◽  
Vol 24 ◽  
pp. 177-182 ◽  
Author(s):  
Chao Zhang ◽  
Kai Chen ◽  
Xiuxin Han ◽  
Jiayuanyuan Fu ◽  
Patricia Douglas ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Diffusion Tensor Imaging ◽  
Diffusion Tensor ◽  
Cord Injury ◽  
Post Traumatic

Optimizing Olfactory Ensheathing Cell Transplantation for Spinal Cord Injury Repair

2020 ◽  
Vol 37 (5) ◽  
pp. 817-829 ◽  
Author(s):  
Aaron D. Gilmour ◽  
Ronak Reshamwala ◽  
Alison A. Wright ◽  
Jenny A.K. Ekberg ◽  
James A. St John
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Cell Transplantation ◽  
Olfactory Ensheathing Cell ◽  
Injury Repair ◽  
Cord Injury

scholarly journals Acute Delivery of EphA4-Fc Improves Functional Recovery after Contusive Spinal Cord Injury in Rats

2013 ◽  
Vol 30 (12) ◽  
pp. 1023-1034 ◽  
Author(s):  
Mark Damien Spanevello ◽  
Sophie Ines Tajouri ◽  
Cornel Mirciov ◽  
Nyoman Kurniawan ◽  
Martin John Pearse ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Functional Recovery ◽  
Cord Injury ◽  
Contusive Spinal Cord Injury

Analysis of high-voltage electrical spinal cord injury using diffusion tensor imaging

2013 ◽  
Vol 260 (11) ◽  
pp. 2876-2883 ◽  
Author(s):  
Suk Hoon Ohn ◽  
Deog Young Kim ◽  
Ji Cheol Shin ◽  
Seung Min Kim ◽  
Woo-Kyoung Yoo ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Diffusion Tensor Imaging ◽  
High Voltage ◽  
Diffusion Tensor ◽  
Cord Injury
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