scholarly journals Vitamin E Intake and Pancreatic Cancer Risk: A Meta-Analysis of Observational Studies

2015 ◽  
Vol 21 ◽  
pp. 1249-1255 ◽  
Author(s):  
Zhanyu Yang
Keyword(s):  
Pancreatic Cancer ◽  
Vitamin E ◽  
Cancer Risk ◽  
Observational Studies ◽  
Meta Analysis ◽  
Pancreatic Cancer Risk

scholarly journals Consumption of Sweet Beverages and Cancer Risk. A Systematic Review and Meta-Analysis of Observational Studies

2020 ◽  
Author(s):  
Fjorida Llaha ◽  
Mercedes Gil-Lespinard ◽  
Pelin Unal ◽  
Izar de Villasante ◽  
Jazmin Castañeda ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Systematic Review ◽  
Pancreatic Cancer ◽  
Cancer Risk ◽  
Observational Studies ◽  
Meta Analysis ◽  
Prostate Cancer Risk ◽  
Significant Positive Association ◽  
Pancreatic Cancer Risk ◽  
Sweetened Beverages

The consumption of sweet beverages, including sugar-sweetened beverages (SSB), artificially sweetened beverages (ASB) and fruit juices (FJ) is associated with the risk of different cardiometabolic diseases and probably with some tumors as well. We carried out a systematic review and meta-analysis of observational studies aimed at evaluating the association between sweet beverage intake and different types of cancer risk. Suitable papers published up to June 2020 were searched through PubMed, Web of Science and SCOPUS databases, using relevant keywords. Overall, 64 studies were identified for the systematic review, of which 27 were selected for the meta-analysis. This was performed by analyzing the multivariable-adjusted OR, RR or HR of the highest compared with the lowest sweet beverage intake categories. Random effects showed significant positive association between SSBs intake and breast (RR: 1.14, 95% CI: 1.01 – 1.30) and prostate cancer risk (RR: 1.18, 95% CI: 1.10 – 1.27), also between FJs and prostate cancer risk (RR: 1.03, 95% CI: 1.01 – 1.05). Associations between SSBs and colorectal and pancreatic cancer risk, FJs and breast, colorectal and pancreatic cancer risk, ASBs and pancreatic cancer risk tended to be positive but did not reach the statistically significant threshold. This study supports the recommendation to limit the consumption of SSBs and FJs for cancer prevention and proposes to further investigate the potential harmful role of ASBs intake in cancer risk.

scholarly journals Consumption of Sweet Beverages and Cancer Risk. A Systematic Review and Meta-Analysis of Observational Studies

Nutrients ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 516
Author(s):  
Fjorida Llaha ◽  
Mercedes Gil-Lespinard ◽  
Pelin Unal ◽  
Izar de Villasante ◽  
Jazmín Castañeda ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Systematic Review ◽  
Pancreatic Cancer ◽  
Cancer Risk ◽  
Observational Studies ◽  
Meta Analysis ◽  
Prostate Cancer Risk ◽  
Significant Positive Association ◽  
Pancreatic Cancer Risk ◽  
Sweetened Beverages

The consumption of sweet beverages, including sugar-sweetened beverages (SSB), artificial-sweetened beverages (ASB) and fruit juices (FJ), is associated with the risk of different cardiometabolic diseases. It may also be linked to the development of certain types of tumors. We carried out a systematic review and meta-analysis of observational studies aimed at examining the association between sweet beverage intake and cancer risk. Suitable articles published up to June 2020 were sourced through PubMed, Web of Science and SCOPUS databases. Overall, 64 studies were identified, of which 27 were selected for the meta-analysis. This was performed by analyzing the multivariable-adjusted OR, RR or HR of the highest sweet beverage intake categories compared to the lowest one. Random effects showed significant positive association between SSB intake and breast (RR: 1.14, 95% CI: 1.01–1.30) and prostate cancer risk (RR: 1.18, 95% CI: 1.10–1.27) and also between FJs and prostate cancer risk (RR: 1.03, 95% CI: 1.01–1.05). Although the statistically significant threshold was not reached, there tended to be positive associations for the following: SSBs and colorectal and pancreatic cancer risk; FJs and breast, colorectal and pancreatic cancer risk; and ASBs and pancreatic cancer risk. This study recommends limiting sweet beverage consumption. Furthermore, we propose to establish a homogeneous classification of beverages and investigate them separately, to better understand their role in carcinogenesis.

Association between Helicobacter pylori and pancreatic cancer risk: a meta-analysis

2015 ◽  
Vol 26 (7) ◽  
pp. 1027-1035 ◽  
Author(s):  
Annaka Schulte ◽  
Nirmala Pandeya ◽  
Jonathan Fawcett ◽  
Lin Fritschi ◽  
Harvey A. Risch ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Helicobacter Pylori ◽  
Cancer Risk ◽  
Meta Analysis ◽  
Pancreatic Cancer Risk

scholarly journals Vitamin B6, vitamin B12 and methionine and risk of pancreatic cancer: a meta-analysis

2020 ◽  
Vol 19 (1) ◽  
Author(s):  
Dan-Hong Wei ◽  
Qi-Qi Mao
Keyword(s):  
Pancreatic Cancer ◽  
Cancer Risk ◽  
Vitamin B12 ◽  
Dose Response ◽  
Vitamin B6 ◽  
Meta Analysis ◽  
Response Relationship ◽  
Dose Response Relationship ◽  
Pancreatic Cancer Risk ◽  
Linear Dose

Abstract Background Nutrients involved in one-carbon metabolism may play a key role in pancreatic carcinogenesis. The aim of this study was to examine the association between pancreatic cancer risk and intake or blood levels of vitamins B6, B12 and methionine via meta-analysis. Methods A systematic search was performed in PubMed, Web of Knowledge and Chinese National Knowledge Infrastructure (CNKI) up to April 2020 to identify relevant studies. Risk estimates and their 95% confidence intervals (CIs) were retrieved from the studies and combined by a random-effect model. Results A total of 18 studies were included in this meta-analysis on the association of vitamin B6, B12 and methionine with pancreatic cancer risk. The combined risk estimate (95% CI) of pancreatic cancer for the highest vs lowest category of vitamin B6 intake and blood pyridoxal 5′-phosphate (PLP, active form of vitamin B6) levels was 0.63 (0.48–0.79) and 0.65 (0.52–0.79), respectively. The results indicated a non-linear dose-response relationship between vitamin B6 intake and pancreatic risk. Linear dose–response relationship was found, and the risk of pancreatic cancer decreased by 9% for every 10 nmol/L increment in blood PLP levels. No significant association were found between pancreatic cancer risk and vitamin B12 intake, blood vitamin B12 levels, methionine intake and blood methionine levels. Conclusion Our study suggests that high intake of vitamin B6 and high concentration of blood PLP levels may be protective against the development of pancreatic cancer. Further research are warranted to confirm the results.

scholarly journals Parity and pancreatic cancer risk: evidence from a meta-analysis of twenty epidemiologic studies

2014 ◽  
Vol 4 (1) ◽  
Author(s):  
Beibei Zhu ◽  
Li Zou ◽  
Juan Han ◽  
Wei Chen ◽  
Na Shen ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Cancer Risk ◽  
Meta Analysis ◽  
Epidemiologic Studies ◽  
Pancreatic Cancer Risk
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