scholarly journals Probing the use of fluorescence spectroscopy as a novel diagnostic tool in patients with rheumatoid arthritis: Applicability in the detection of secondary amyloidosis

2012 ◽  
Vol 18 (10) ◽  
pp. BR414-BR418
Author(s):  
Sławomir Jeka ◽  
Paweł Zuchowski ◽  
Mariusz Korkosz ◽  
Monika Prochorec-Sobieszek ◽  
Jacek J. Fisz
2009 ◽  
Vol 28 (9) ◽  
pp. 1113-1116 ◽  
Author(s):  
Hiroe Sato ◽  
Takehito Sakai ◽  
Toshiaki Sugaya ◽  
Yasuhiro Otaki ◽  
Kana Aoki ◽  
...  

1986 ◽  
Vol 11 (1) ◽  
pp. 120-122
Author(s):  
A. I. ROTH ◽  
B. N. STULBERG ◽  
E. J. FLEEGLER ◽  
G. H. BELHOBEK

This is a case report of a fifty-nine-year-old rheumatoid arthritic woman who developed lack in finger extension bilaterally. These deficits had two completely different aetiologies, Posterior Interosseous Nerve (PIN) Syndrome and extensor tendon rupture. No previous report in the literature has used elbow arthrography as a diagnostic tool in a patient with PIN Syndrome. Elbow arthrography confirmed the abnormality at this joint and aided in appropriate management.


Biomolecules ◽  
2018 ◽  
Vol 8 (4) ◽  
pp. 136 ◽  
Author(s):  
Levent Kilic ◽  
Abdulsamet Erden ◽  
Yusuf Sener ◽  
Berkan Armagan ◽  
Alper Sari ◽  
...  

Secondary amyloid A (AA) amyloidosis is a late and serious complication of poorly controlled, chronic inflammatory diseases. Rheumatoid arthritis (RA) patients with poorly controlled, longstanding disease and those with extra-articular manifestations are under risk for the development of AA amyloidosis. Although new drugs have proven to be significantly effective in the treatment of secondary AA amyloidosis, no treatment modality has proven to be ideal. To date, only in small case series preliminary clinical improvement have been shown with rituximab therapy for AA amyloidosis secondary to RA that is refractory to TNF-α inhibitors (TNF-i) therapy. In these case series, we assessed the efficacy and safety of rituximab therapy for patients with RA and secondary amyloidosis. Hacettepe University Biologic Registry was developed at 2005. The data of the RA patients who were prescribed a biological drug were recorded regularly. Patients with biopsy proven AA amyloidosis patients were screened. Of 1022 RA patients under biologic therapy, 0.7% patients had clinically apparent histologically confirmed amyloidosis. Four of seven patients who were prescribed rituximab at least one infusion enrolled to those case series. Two of four patients showed significant clinical improvement and one of them also had decrease in proteinuria and the other one had stable renal function and proteinuria. The main goal for the treatment of AA amyloidosis is to control the activity of the underlying disorder. In this study, we showed that rituximab may be an effective treatment in RA patients with amyloidosis who were unresponsive to conventional disease modifying anti-rheumatic drugs (DMARDs) and/or TNFi.


1995 ◽  
Vol 18 (1) ◽  
pp. 83-89
Author(s):  
Kazuki Tanimoto ◽  
Minoru Nakamura ◽  
Kaoru Okada ◽  
Kohei Nagasawa ◽  
Yoshiyuki Niho

2014 ◽  
Vol 3 (2) ◽  
pp. 237-243 ◽  
Author(s):  
Shunsuke Yamada ◽  
Akihiro Tsuchimoto ◽  
Yoshiki Kaizu ◽  
Masatomo Taniguchi ◽  
Kosuke Masutani ◽  
...  

1994 ◽  
Vol 52 (1) ◽  
pp. 31-38 ◽  
Author(s):  
N. Ramanujam ◽  
M.F. Mitchell ◽  
A. Mahadevan ◽  
S. Thomsen ◽  
E. Silva ◽  
...  

2015 ◽  
Vol 42 (7) ◽  
pp. 1119-1122 ◽  
Author(s):  
Sunil Das ◽  
DoQuyen Huynh ◽  
Hong Yang ◽  
Arnoldas Ceponis ◽  
Arthur Kavanaugh

Objective.To assess salivary gland ultrasonography (US) as a diagnostic tool for secondary Sjögren syndrome (sSS) in patients with rheumatoid arthritis (RA).Methods.Salivary gland US images from 30 patients with RA were graded using a validated semiquantitative scoring system. Sicca symptoms, oral health, and RA disease activity were assessed.Results.US changes consistent with SS were found in 40% of patients. Patients with higher US scores had more sicca symptoms as well as higher RA activity and poorer oral health.Conclusion.Salivary gland US may aid the diagnosis of sSS in patients with RA.


2009 ◽  
Vol 0 (3) ◽  
pp. 50
Author(s):  
Irina Mikhailovna Marusenko ◽  
Ya A Avdeyeva ◽  
I I Polskaya

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