scholarly journals Effects of In Utero Exposure to Bisphenol A on mRNA Expression of Arylhydrocarbon and Retinoid Receptors in Murine Embryos

2005 ◽  
Vol 51 (3) ◽  
pp. 315-324 ◽  
Author(s):  
Hanako NISHIZAWA ◽  
Maki MORITA ◽  
Miki SUGIMOTO ◽  
Satoshi IMANISHI ◽  
Noboru MANABE
Keyword(s):  
Bisphenol A ◽  
Mrna Expression ◽  
In Utero ◽  
In Utero Exposure ◽  
Retinoid Receptors ◽  
Murine Embryos

scholarly journals Effects of In Utero Exposure to Bisphenol A on Expression of RARα and RXRα mRNAs in Murine Embryos

2003 ◽  
Vol 49 (6) ◽  
pp. 539-545 ◽  
Author(s):  
Hanako NISHIZAWA ◽  
Noboru MANABE ◽  
Maki MORITA ◽  
Miki SUGIMOTO ◽  
Satoshi IMANISHI ◽  
...  
Keyword(s):  
Bisphenol A ◽  
In Utero ◽  
In Utero Exposure ◽  
Murine Embryos

Low dose effect of in utero exposure to bisphenol A and diethylstilbestrol on female mouse reproduction

2002 ◽  
Vol 16 (2) ◽  
pp. 117-122 ◽  
Author(s):  
Shizuka Honma ◽  
Atsuko Suzuki ◽  
David L. Buchanan ◽  
Yoshinao Katsu ◽  
Hajime Watanabe ◽  
...  
Keyword(s):  
Bisphenol A ◽  
Female Mouse ◽  
Low Dose ◽  
In Utero ◽  
Dose Effect ◽  
In Utero Exposure

In utero exposure to bisphenol-A disrupts key elements of retinoid system in male mice offspring

2019 ◽  
Vol 126 ◽  
pp. 142-151 ◽  
Author(s):  
Javier Esteban ◽  
Marina Serrano-Maciá ◽  
Ismael Sánchez-Pérez ◽  
Paloma Alonso-Magdalena ◽  
María de la Cruz Pellín ◽  
...  
Keyword(s):  
Bisphenol A ◽  
In Utero ◽  
In Utero Exposure ◽  
Male Mice

scholarly journals In Utero Exposure to Low Doses of Bisphenol A Lead to Long-term Deleterious Effects in the Vagina

Neoplasia ◽  
2002 ◽  
Vol 4 (2) ◽  
pp. 98-102 ◽  
Author(s):  
G. Schönfelder ◽  
B. Flick ◽  
E. Mayr ◽  
C. Talsness ◽  
M. Paul ◽  
...  
Keyword(s):  
Bisphenol A ◽  
In Utero ◽  
In Utero Exposure ◽  
Low Doses

scholarly journals Fetal Bisphenol-A Induced Changes in Murine Behavior and Brain Gene Expression Persisted in Adult-aged Offspring

Endocrinology ◽  
2020 ◽  
Vol 161 (12) ◽  
Author(s):  
Zhihao Wang ◽  
Myles H Alderman ◽  
Cyrus Asgari ◽  
Hugh S Taylor
Keyword(s):  
Gene Expression ◽  
Locomotor Activity ◽  
Bisphenol A ◽  
In Utero ◽  
Learning Ability ◽  
Long Term Memory ◽  
In Utero Exposure ◽  
Term Memory ◽  
Brain Gene Expression

Abstract In utero Bisphenol A (BPA) exposure has been linked to many deficits during brain development, including sexual differentiation, behavior, and motor coordination. Yet, how BPA induces these disorders and whether its effects are long lasting are largely unknown. In this study, using a mouse model, we demonstrated that in utero exposure to an environmentally relevant dose of BPA induced locomotor deficits, anxiety-like behavior, and declarative memory impairments that persisted into old age (18 months). Compared to the control animals, the BPA-exposed mice had a significant decrease in locomotor activity, exploratory tendencies, and long-term memory, and an increase in anxiety. The global brain gene expression profile was altered permanently by BPA treatment and showed regional and sexual differences. The BPA-treated male mice had more changes in the hippocampus, while female mice experienced more changes in the cortex. Overall, we demonstrate that in utero exposure to BPA induces permanent changes in brain gene expression in a region-specific and sex-specific manner, including a significant decrease in locomotor activity, learning ability, long-term memory, and an increase in anxiety. Fetal/early life exposures permanently affect neurobehavioral functions that deteriorate with age; BPA exposure may compound the effects of aging.

scholarly journals In Utero Exposure to Bisphenol A Shifts the Window of Susceptibility for Mammary Carcinogenesis in the Rat

2010 ◽  
Vol 118 (11) ◽  
pp. 1614-1619 ◽  
Author(s):  
Angela M. Betancourt ◽  
Isam A. Eltoum ◽  
Renee A. Desmond ◽  
Jose Russo ◽  
Coral A. Lamartiniere
Keyword(s):  
Bisphenol A ◽  
Mammary Carcinogenesis ◽  
In Utero ◽  
In Utero Exposure

scholarly journals In Utero Exposure to Bisphenol A Recapitulates the Fetal Testis Cord Dysgenesis Phenotype of Activin A Knockout Mice.

2010 ◽  
Vol 83 (Suppl_1) ◽  
pp. 290-290
Author(s):  
Denise R. Archambeault ◽  
Rupesh K. Gupta ◽  
Jeff Chen-Che Huang ◽  
Jodi A. Flaws ◽  
Humphrey H.C. Yao
Keyword(s):  
Bisphenol A ◽  
Knockout Mice ◽  
In Utero ◽  
Activin A ◽  
In Utero Exposure ◽  
Fetal Testis ◽  
Testis Cord
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