Fine needle aspiration cytology in the investigation of breast lumps at the University Teaching Hospital in Lusaka, Zambia

2008 ◽  
Vol 38 (4) ◽  
pp. 245-247
Author(s):  
Kasonde Bowa ◽  
Jim Jewel ◽  
Victor Mudenda
Keyword(s):  
Teaching Hospital ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
University Teaching ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology ◽  
Breast Lumps ◽  
The University

The study was undertaken to determine the value of fine needle aspiration cytology (FNAC) in the investigation of breast lumps at the University Teaching Hospital (UTH) in Lusaka, Zambia. This technique, which has been shown to be cheap, simple and accurate has not been in common use at this institution. FNAC and open biopsy (OB) were performed on 56 patients who presented with a breast lump and the results compared, in order to determine the accuracy of FNAC. FNAC was found to have a sensitivity of 72% and specificity of 100%. This level of accuracy compares favourably with the quality assurance criteria set for breast FNAC by the Royal College of Pathologists in the British National Health Service (NHS).

scholarly journals FINE NEEDLE ASPIRATION CYTOLOGY OF BREAST LUMP IN T.U. TEACHING HOSPITAL

2003 ◽  
Vol 41 (143) ◽  
pp. 388-91
Author(s):  
Jagat Singh Pandey ◽  
G Sayami ◽  
S Dali ◽  
H G Shrestha ◽  
B Shrestha ◽  
...  
Keyword(s):  
Teaching Hospital ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
False Negative ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Rapid Diagnostic Method ◽  
Needle Aspiration Cytology ◽  
Breast Lumps

This is a retrospective study of fine needle aspiration cytology of breast lesionsperformed between May 1998 and April 2000. During this period, a total of 2001 fineneedle aspirations were done in the Tribhuvan Universtiy Teaching Hospital (TUTH),of which 470 (23.48 %) were of the breast. Fibrocystic disease found to be the mostfrequent and was diagnosed in 183 cases (38.9%). Fibroadenoma was the third commonpathological condition, numbering 61 (12.9%). Malignant conditions of the breastwere 72 cases (15.3%).During these two years, histological diagnosis was available in 154 cases. Histologicalexamination revealed benign conditions in 74 cases (48%), malignancy in 59 cases(38.3%) and inflammatory & lactational changes in 21 cases (13.7%). Out of these154 cases, 71 cases had also undergone fine needle aspiration cytology. The 36 casesdiagnosed as benign cytologically, 34 cases were also benign histologically, whereas 2cases turned out to be malignant. Out of 37 cases that were histologically malignant,on cytology 35 cases were diagnosed as malignant. The sensitivity and specificity ofcytopathological diagnosis for breast lesions was 100% and 94.6% respectively.Inflammatory lesions correlated well cytologically and histolgically.FNAC is a safe and rapid diagnostic method for evaluation of various lesions. However,there are possibilities of false negative and false positive results because of wide rangeof appearance of breast lesions.Key Words: Breast lumps, Fine Needle Aspiration Cytology, Benign Lesions,Malignant Lesions, Histopathology and Correlation.

Cytopathological Evaluation of Thyroid Lesions Based on Bethesda System in Patients Attending Birat Medical College and Teaching Hospital

2020 ◽  
Vol 22 (4) ◽  
pp. 260-265
Author(s):  
Neeta Kafle ◽  
B Koirala ◽  
SU Kafle ◽  
M Singh ◽  
A Sinha
Keyword(s):  
Teaching Hospital ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Medical College ◽  
Bethesda System ◽  
Needle Aspiration Cytology ◽  
Thyroid Lesions

More than 50% of the world’s population has at least a thyroid nodule. Detail clinical examination and radiology may help in diagnosing thyroid lesions but the management depends upon the cytopathological diagnosis. Optimum use of fine needle aspiration cytology (FNAC) and better understanding of cytomorphological characteristic of thyroid lesions by using Bethesda system, triaging of patients who are to be treated medically or surgically is more accurate. The objective of this present study is cytopathological evaluation of thyroid lesions based on Bethesda System in patients attending Birat Medical College and Teaching Hospital. The objective was also to correlate the cytological findings with histopathological findings where ever possible. A total of 104 patients with thyroid lesions underwent fine needle aspiration cytology in a period of a year (September 1, 2019 to August 31, 2020). Cytological features were evaluated and classified according to the Bethesda system. Histopathological features were evaluated and correlated wherever available. Among 104 patients with thyroid lesions 93 were female and 11 were male. Four cases turned out to be non diagnostic, 85 benign, three Atypia of undetermined significance, three Suspicious for follicular neoplasm and eight Suspicious of malignancy and one Malignant according to Bethesda system. Histopathology specimen was received in 31 patients out of whom 20 (64.5%) patients were reported as colloid nodule, two follicular adenoma, one Hurthle cell adenoma, six papillary carcinoma and two follicular carcinoma. Medullary carcinoma and anaplastic carcinoma were not seen in the patients evaluated. Specificity and sensitivity of fine needle aspiration cytology was 94.7% and 88.9% respectively. Thus reporting thyroid lesions FNAC with Bethesda system allow a more specific cytological diagnosis.

scholarly journals Fine Needle Aspiration Cytology of Palpable Breast Lumps - Their Cytological Spectrum and Histopathological Correlation

KYAMC Journal ◽  
2017 ◽  
Vol 7 (2) ◽  
pp. 780-786
Author(s):  
Shaheen Akter ◽  
Md Jahidul Islam ◽  
Md Shariful Haque
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Breast Lump ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Histopathological Correlation ◽  
Palpable Breast ◽  
Needle Aspiration Cytology ◽  
Breast Lumps

Background: With the advent of fine needle aspiration cytology (FNAC), the approach to diagnosis and management of breast lumps has been revolutionized and it has high sensitivity and specificity.Aim: In this study we analyze the spectrum of FNAC diagnoses in breast lumps and compare the diagnostic accuracy of fine FNAC in differentiating the benign and malignant lesions of breast lumps with histopathological correlation.Materials & Methods: Two years prospective study was conducted in our institution and in that 490 aspirations, including 6 bilateral were performed. Suppurative and inflammatory lesions were excluded from the total aspirates. The cytological diagnosis was classified into 3 groups benign, suspicious and malignant. After this reporting all the available 94 cases were later subjected to mastectomy or open/excision biopsy and followed-up by histopathological confirmation. Later diagnostic accuracy of cytology reporting was compared with that of histopathology.Results: A total of 490 FNAC cases were reported including 373 as benign, 4 as suspicious for carcinoma and 113 as carcinoma. Majorities were premenopausal females and commonest age group was 31-40 years. Among them only 94 cases were followed-up by histopathologic confirmation. In histopathological correlation study, we had accuracy rate of 100% for benign lesion and 92.10% for malignant lesion with false negative rate of 7.90% and false positive rate of zero with fine needle aspiration cytology in the diagnosis of palpable breast lump. The overall sensitivity of fine needle aspiration in diagnosing the palpable breast lump is 92.10%, specificity is 100%, positive predictive value is 100% and negative predictive value is 94.91%.Conclusion: FNAC in experienced hands is a very useful tool with very high specificity and rare false positive result. Sensitivity can be further improved with clinical and imaging correlation.KYAMC Journal Vol. 7, No.-2, Jan 2017, Page 780-786

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