Fine-needle aspiration cytology of the thyroid: Ten years experience in a community teaching hospital

2006 ◽  
Vol 34 (2) ◽  
pp. 93-96 ◽  
Author(s):  
Howard Her-Juing Wu ◽  
Jennifer N. Jones ◽  
Jailan Osman
2020 ◽  
Vol 22 (4) ◽  
pp. 260-265
Author(s):  
Neeta Kafle ◽  
B Koirala ◽  
SU Kafle ◽  
M Singh ◽  
A Sinha

More than 50% of the world’s population has at least a thyroid nodule. Detail clinical examination and radiology may help in diagnosing thyroid lesions but the management depends upon the cytopathological diagnosis. Optimum use of fine needle aspiration cytology (FNAC) and better understanding of cytomorphological characteristic of thyroid lesions by using Bethesda system, triaging of patients who are to be treated medically or surgically is more accurate. The objective of this present study is cytopathological evaluation of thyroid lesions based on Bethesda System in patients attending Birat Medical College and Teaching Hospital. The objective was also to correlate the cytological findings with histopathological findings where ever possible. A total of 104 patients with thyroid lesions underwent fine needle aspiration cytology in a period of a year (September 1, 2019 to August 31, 2020). Cytological features were evaluated and classified according to the Bethesda system. Histopathological features were evaluated and correlated wherever available. Among 104 patients with thyroid lesions 93 were female and 11 were male. Four cases turned out to be non diagnostic, 85 benign, three Atypia of undetermined significance, three Suspicious for follicular neoplasm and eight Suspicious of malignancy and one Malignant according to Bethesda system. Histopathology specimen was received in 31 patients out of whom 20 (64.5%) patients were reported as colloid nodule, two follicular adenoma, one Hurthle cell adenoma, six papillary carcinoma and two follicular carcinoma. Medullary carcinoma and anaplastic carcinoma were not seen in the patients evaluated. Specificity and sensitivity of fine needle aspiration cytology was 94.7% and 88.9% respectively. Thus reporting thyroid lesions FNAC with Bethesda system allow a more specific cytological diagnosis.


2003 ◽  
Vol 41 (143) ◽  
pp. 388-91
Author(s):  
Jagat Singh Pandey ◽  
G Sayami ◽  
S Dali ◽  
H G Shrestha ◽  
B Shrestha ◽  
...  

This is a retrospective study of fine needle aspiration cytology of breast lesionsperformed between May 1998 and April 2000. During this period, a total of 2001 fineneedle aspirations were done in the Tribhuvan Universtiy Teaching Hospital (TUTH),of which 470 (23.48 %) were of the breast. Fibrocystic disease found to be the mostfrequent and was diagnosed in 183 cases (38.9%). Fibroadenoma was the third commonpathological condition, numbering 61 (12.9%). Malignant conditions of the breastwere 72 cases (15.3%).During these two years, histological diagnosis was available in 154 cases. Histologicalexamination revealed benign conditions in 74 cases (48%), malignancy in 59 cases(38.3%) and inflammatory & lactational changes in 21 cases (13.7%). Out of these154 cases, 71 cases had also undergone fine needle aspiration cytology. The 36 casesdiagnosed as benign cytologically, 34 cases were also benign histologically, whereas 2cases turned out to be malignant. Out of 37 cases that were histologically malignant,on cytology 35 cases were diagnosed as malignant. The sensitivity and specificity ofcytopathological diagnosis for breast lesions was 100% and 94.6% respectively.Inflammatory lesions correlated well cytologically and histolgically.FNAC is a safe and rapid diagnostic method for evaluation of various lesions. However,there are possibilities of false negative and false positive results because of wide rangeof appearance of breast lesions.Key Words: Breast lumps, Fine Needle Aspiration Cytology, Benign Lesions,Malignant Lesions, Histopathology and Correlation.


2008 ◽  
Vol 38 (4) ◽  
pp. 245-247
Author(s):  
Kasonde Bowa ◽  
Jim Jewel ◽  
Victor Mudenda

The study was undertaken to determine the value of fine needle aspiration cytology (FNAC) in the investigation of breast lumps at the University Teaching Hospital (UTH) in Lusaka, Zambia. This technique, which has been shown to be cheap, simple and accurate has not been in common use at this institution. FNAC and open biopsy (OB) were performed on 56 patients who presented with a breast lump and the results compared, in order to determine the accuracy of FNAC. FNAC was found to have a sensitivity of 72% and specificity of 100%. This level of accuracy compares favourably with the quality assurance criteria set for breast FNAC by the Royal College of Pathologists in the British National Health Service (NHS).


Author(s):  
Inclub Dhungana ◽  
Krishna Koirala ◽  
Ashish Khadgi ◽  
Niraj Khatri Sapkota

<p><strong>Background: </strong>Palpable neck swelling is a common clinical manifestation in otolaryngology. Rapid, inexpensive and simple method of examination for the diagnosis of such superficial masses is fine needle aspiration cytology (FNAC). Objectives were to evaluate the usage of fine needle aspiration cytology as a first-line tool for diagnosis, accuracy compared with histopathology.</p><p><strong>Method</strong>: A hospital based prospective cross sectional was conducted by taking 65 patients with neck swelling presentation thyroid swelling were highest in number followed by lymph node and salivary, in which female were 43 (66.15%) and male were 22 (33.85%), the age group ranged from 6 to 75 years in ear, nose, throat (ENT) OPD of Manipal teaching hospital between 15<sup>th </sup>November 2015 to 15<sup>th</sup> May 2017. FNAC along with histopathological examination (HPE) were done and compared. For data analysis SPSS 20 version was used. The sensitivity, specificity and accuracy rates were calculated. The Cohen’s Kappa statistical test was employed.</p><p><strong>Results</strong><strong>: </strong>The overall sensitivity and specificity of FNAC was 90.76% and 98.075% respectively in determining the various pathologies. The diagnostic accuracy of FNAC in comparison to histopathology was 92.25%. This study showed almost perfect correlation (measure of agreement) between FNAC and final histopathology diagnosis of neck swellings from Cohen’s Kappa test.</p><p><strong>Conclusions: </strong>FNAC is a safe, simple and rapid method with a high sensitivity and specificity that can be done in diagnosing wide range of neck swellings.</p>


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