scholarly journals A novel approach to hyperemesis gravidarum: evaluation by a visual analogue scale score and treatment with transdermal clonidine

2011 ◽  
Vol 4 (4) ◽  
pp. 156-159 ◽  
Author(s):  
Aldo Maina ◽  
Tullia Todros

Objective A preliminary report on the symptomatic effect of clonidine in severe hyperemesis gravidarum (HG). Design Observational. Settting Hospital based: Ospedale Sant'Anna, Torino, Italy. Population Twelve pregnant women, 8–16 weeks, affected by severe, refractory HG. Methods Assessment by two clinical score indexes: Pregnancy Unique Quantification of Emesis (PUQE) score and a Visual Analogue Scale (VAS) 5-item questionnaire, filled out daily, to detect subjective improvement or worsening of symptoms. Main outcome measures PUQE score and VAS score before and after transdermal clonidine treatment. Results We found substantial improvement of symptoms and severity score indexes after four and 14 days. The comparison of pretreatment and post-treatment scores shows a significant statistical difference P < 0.0001. Conclusion Transdermal clonidine may be considered as a treatment for resistant severe HG.

2007 ◽  
Vol 30 (1) ◽  
pp. 47-49 ◽  
Author(s):  
Elaine Henna ◽  
Monica L Zilberman ◽  
Valentim Gentil ◽  
Clarice Gorenstein

OBJECTIVE: To test a reliable and easily administered frustration-induction procedure for experimental research. METHOD: One hundred volunteers (81 women, mean age ± SD 34.2 ± 8 years) physically and psychiatrically healthy submitted to the frustration induction procedure were prevented from reaching reward level scores. Subjective aggressiveness feelings related to frustration were self-rated in a 13-item visual analogue scale before and after the procedure. RESULTS: Significant increases in aggressiveness-related feelings were detected in 12 of the 13 items. This was consistent with the observed overt behavior of the subjects during the task. CONCLUSIONS: The frustration-induction procedure is a simple, easy to administer frustration-induction procedure that can be used in experimental studies in normal subjects.


1998 ◽  
Vol 119 (3) ◽  
pp. 288-292 ◽  
Author(s):  
R. W. Clarke ◽  
M. P. J. Yardley ◽  
C. M. Davies ◽  
A. Panarese ◽  
R. T. Clegg ◽  
...  

In a randomized, controlled trial, 62 patients (47 men and 15 women) with severe antisocial snoring, but no sleep apnea, were allocated to one of three surgical treatments. These were uvulopalato-pharyngoplasty, laser palatoplasty, and diathermy palatoplasty. Postoperative morbidity was measured on a visual analogue scale of severity of pain, dysphagia, and nasal regurgitation at 1, 2, and 7 days after the operation. Efficacy of each procedure was measured by asking the sleeping partner to record the severity of snoring before and after the operation, again on a visual analogue scale. Measurements were taken at 1, 3, and 6 months. There were no significant differences in early postoperative morbidity among the treatment groups. Diathermy palatoplasty is a new technique for the relief of snoring that is associated with low morbidity and requires little in the way of expensive equipment.


2021 ◽  
Vol 28 (11) ◽  
pp. 1552-1556
Author(s):  
Samara Siddique ◽  
Yasir Imran ◽  
Asma Rizwan ◽  
Sahira Aaraj

Objectives: To evaluate the role of Diacerein among patients with OA. Study Design: Retrospective Case Series. Setting: Mayo Hospital, Lahore. Period: April 2020 to September 2020. Material & Methods: The study was conducted among forty patients with OA (grade II to IV according to ACR criteria) at Department of Rheumatology (EMW), Mayo Hospital, Lahore. Baseline WOMAC (Western Ontario and McMaster Universities Arthritis Index) and VAS (Visual Analogue Scale) was noted. Diacerine, 100mg in bd (twice a day) dose was given for 6 months. After 6 months, WOMAC and VAS were noted and %age improvement was calculated. Results: The mean WOMAC at presentation was 48.78+6.42 and after treatment was 36.20+20 (p<0.05). The mean VAS before and after treatment was 5.88+1.20 and 3.58+3.22, respectively (p<0.05). A 20% improvement was seen among 40% patients. The efficacy of the drug was labeled as yes in 40% patients. One (2.5%) patients suffered from diarrhea, and one (2.5%) patient had raised LFTs after treatment. Conclusion: Diacerine significantly improves the mean WOMAC and VAS score after 6 months of therapy. The efficacy is also high. So, it can be considered as an alternative drug among symptomatic patients with OA in whom the symptoms do not improve after conventional analgesics.


2013 ◽  
Vol 127 (6) ◽  
pp. 574-577 ◽  
Author(s):  
G J Watson ◽  
G Trainor ◽  
A E Camilleri

AbstractObjective:To demonstrate that Blu-tack is equally effective at attenuating sound as over-the-counter ear plugs.Methods:Nineteen healthy volunteers had their hearing thresholds assessed before and after the insertion of over-the-counter ear plugs. The results were compared with hearing thresholds following the insertion of Blu-tack. Thresholds were tested at: 0.5, 1, 2, 3, 4, 6 and 8 kHz. The differences were compared, and p values of less than 0.02 were regarded as significant. Using a visual analogue scale, volunteers were asked to assess the comfort and ease of insertion of the ear plugs and Blu-tack, and their peace of mind whilst using the ear plugs and Blu-tack.Results:Blu-tack was less effective at attenuating sound at low frequencies, but was as effective as over-the-counter ear plugs at attenuating sound above 3 kHz. Blu-tack was significantly more comfortable to wear (p = 0.006). There was no difference in terms of ease of insertion and peace of mind.Conclusion:Blu-tack can be regarded as a comfortable alternative to over-the-counter ear plugs for the attenuation of everyday sound.


2020 ◽  
Vol 10 (23) ◽  
pp. 8398
Author(s):  
Hanna Sobczak-Zagalska ◽  
Katarzyna Emerich

Background: Stabilization of luxated, avulsed, and root-fractured teeth is a part of the dental trauma treatment. The aim of the study was to assess the power chain and its comparison with two commonly used splinting materials. Methods: The evaluated splints were a wire-composite splint (WCS) with a diameter of 0.5 mm, a titanium trauma splint (TTS), and a power chain-composite splint (PCS). The splints were all fixed to the labial surfaces of permanent maxillary incisors in 10 human volunteers. The following parameters were measured: tooth mobility with Periotest before and after the splint application and removal, Aproximal Plaque Index (API), Sulcus Bleeding Index (SBI), and time needed to apply and to remove the splint. Each volunteer was also given a visual analogue scale (VAS) questionnaire to assess his/her subjective attitudes to splint materials. Results: The PCS was the most flexible material as it had the lowest horizontal Periotest values. For the two other methods, horizontal splint effects were similar and were also low. The PCS was the fastest to apply and remove and was also the most aesthetic splint. Conclusion: In this experimental study among volunteers, all three tested materials were found suitable for splinting the PCS has some advantages worth it to be further evaluated clinically in trauma patients.


2011 ◽  
Vol 15 (02) ◽  
pp. 156-162
Author(s):  
Carlos Eduardo Monteiro Zappelini ◽  
Luana Gonçalves Oliveira ◽  
Luciana Campoy Giro Basile ◽  
Everardo Andrade da Costa ◽  
Rodrigo Ubiratan Franco Teixeira

Summary Introduction: The measurement of the peak nasal inspiratory flow (PNIF) is easily and swiftly obtained, but hardly spread in Brazil though. On the other hand, the visual analogue scale (VAS) for nasal obstruction is a subjective measurement that can also be used. Objective: To evaluate the correlation between PNIF and VAS for nasal obstruction before and after occurring a change in the nasal patency caused by the topic vasoconstriction. Study outline: Non-randomized clinical and experimental study. Method: 60 volunteers, including patients, doctors, nurses and administrative assistants of the institution were submitted to PNIF and VAS examinations before and after the nasal vasoconstriction with oxymetazoline chloride at 0.05%. Results: The average value found for pre-vasoconstriction VAS was 4.1 and, for post-vasoconstriction, it was 2. This represented a 44% range between the measurements. With regard to PNIF values, the average found when measuring the vasoconstriction was 151 l/min and 178 l/min after vasoconstriction, showing a 20% increase. At the pre-vasoconstrictor moment, increasing a point in average VAS value corresponds to a 3.8% decrease in average PNIF value. In the post-vasoconstriction, each increase of a point in average VAS value corresponds to a 4.5% decrease in average PNIF value. Conclusion: There was an important correlation between the objective measurement of the nasal obstruction through PNIF and the subjective measurement provided by VAS before nasal vasoconstriction. A similar correlation could also be observed after using the decongestant.


2018 ◽  
Vol 21 (17) ◽  
pp. 3216-3222 ◽  
Author(s):  
Misa Shimpo ◽  
Rie Akamatsu

AbstractObjectivePortion sizes and bowl sizes may be related to food intake and perceived fullness. The objective of the present study was to investigate the effects of portion size and bowl size and possible interactions between these variables on food intake and fullness in a sample of Japanese men.DesignParticipants ate four different experimental meals across four weeks and completed questionnaires about their fullness using a visual analogue scale administered before and after meals. The four meal patterns included consistent portions of several foods commonly eaten together in typical Japanese meals, along with 150 g of rice served in a small rice bowl (diameter of 11·5 cm), 150 g of rice served in a large rice bowl (diameter of 13·5 cm), 250 g of rice served in a small rice bowl or 250 g of rice served in a large rice bowl.SettingTokyo.SubjectTwenty-one adult men participated in the study.ResultsPortion size had a significant main effect on rice intake (F(1,20)=83, P<0·001) and fullness (F(1,20)=8·0, P=0·010), but no significant effects of bowl size on the outcome variables were found. The interactions between portion size and bowl size on intake and fullness were not significant.ConclusionsThe sample of Japanese men showed an influence of portion size on food intake. Further research is needed to clarify the combined effects of bowl size and portion size on intake and fullness.


2020 ◽  
Vol 11 (4) ◽  
pp. 7160-7165
Author(s):  
Chitra Khanwelkar ◽  
Kartik Peethambaran ◽  
Sujata Jadhav

Oral proteolytic enzymes like serratiopeptidase are very commonly used by clinicians either alone or in combination with non-steroidal anti-inflammatory drugs for analgesia and anti-inflammatory purpose. As the activity of these drugs is not proved in trials, and they are not listed in any country's official pharmacopoeia, it was planned to study their effect in osteoarthritis patients. Two groups (n= 30 each) of diagnosed knee osteoarthritis patients, were treated with diclofenac 50 mg twice a day (BID) and serratiopeptidase 10mg three times a day (TID) + Diclofenac 50 mg BID for two weeks. The pain and difficulty in daily activities were assessed by Visual Analogue Scale (VAS) and Western Ontario and Mc Masters Universities Osteoarthritis (WOMAC OA) index scale before and after the treatment.  Highly significant improvement in both scales was seen in both groups. There was no statistically significant difference in the improvements found in both groups.  Addition of serratiopeptidase has not potentiated analgesic and anti-inflammatory effects of diclofenac. Thus, the analgesic and anti-inflammatory efficacy of serratiopeptidase are not proved.


2007 ◽  
Vol 63 (2) ◽  
Author(s):  
A. O. Akinpelu ◽  
A. C. Odole ◽  
B. O. A. Adegoke ◽  
A. F. Adeyini

Background and Aim: Development of outcome measures remains a focus of health research in the 21st century. Outcome measures originally developed for the Nigerian environment are very rare. The aims of this study were to develop an outcome measure for management of hip and knee arthritic conditions, and to investigate the validity and responsiveness of it. Methods: The Ibadan Knee/Hip Osteoarthritis Measure (IKHOAM)was developed from other measures found in literature, as well as complaints of attending patients. Forty nine patients with pain from knee and/or hip osteoarthritis, the OA group (OAG) and 49 individuals without knee or hip pain, the pain-free group (PFG) were assessed, using the IKHOAM. The OAG was assessed on IKHOAM and the Visual Analogue Scale (VAS) before and after a 6-week physiotherapy programme. Results: Significant differences between IKHOAM scores of the OAG and PFG and between IKHOAM scores of OAG pre and post 6-week physiotherapy programme, as well as the significant negative correlations between changes in IKHOAM and VAS scores of OAG before and after the 6-week physiotherapy programme were demonstrated. Conclusion: IKHOAM demonstrated initial criteria towards validity and responsiveness and may be used in a Nigerian population of OA knee/hip individuals and similar environments.


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