Imaging findings and accuracy of core needle biopsy in mucinous carcinoma of the breast

2011 ◽  
Vol 52 (2) ◽  
pp. 128-133 ◽  
Author(s):  
MK Bode ◽  
T Rissanen
Keyword(s):  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Mucinous Carcinoma ◽  
Imaging Findings ◽  
Carcinoma Of The Breast ◽  
Core Needle

scholarly journals A difficult-to-diagnose fibromatosis-like metaplastic carcinoma of the breast: a case report

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Daiki Takatsuka ◽  
Hiroyuki Ogura ◽  
Yuko Asano ◽  
Akiko Nakamura ◽  
Kei Koizumi ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Metaplastic Carcinoma ◽  
Low Grade ◽  
Carcinoma Of The Breast ◽  
Breast Ultrasonography ◽  
Core Needle ◽  
Spindle Cells

Abstract Background Fibromatosis-like metaplastic carcinoma (FLMCa), classified as a metaplastic carcinoma of the breast, is a very rare type of metaplastic carcinoma. We report a case of FLMCa that was difficult to diagnose. Case presentation The patient was a 56-year-old postmenopausal woman who presented with a left-sided breast mass. A 1.3-cm irregular mass was found in the lower outer quadrant of the left breast on breast ultrasonography. She underwent core needle biopsy and vacuum-assisted biopsy, but the pathological findings only revealed inflammatory cell infiltration and a high level of fibrosis, with no malignant findings. At 3 months follow-up, she underwent a repeat breast ultrasonography, which revealed an increase in the size of the mass to 1.8 cm, and a repeat core needle biopsy, which showed a few spindle cells and squamous cells positive for cytokeratin (CK)5/6 and AE1/AE3, leading to the suspicion of FLMCa. Since the amount of tissue was insufficient to establish a definitive diagnosis, she underwent a lumpectomy. We found low-grade and slightly atypical spindle cells and partly atypical spindle cell carcinoma and squamous cell carcinoma. CK5/6 and α-SMA were positive, thus confirming FLMCa. Because the margins on the edge of the nipple side and anterior side were “ink on tumor”, she underwent a mastectomy and sentinel lymph node biopsy. After the surgery, she received adjuvant chemotherapy. At 3 years and 8 months of follow-up, no recurrent or metastatic lesions were identified in her body. Conclusions FLMCa should be considered in the differential diagnosis when collagenous fibers are proliferating and malignancy is clinically suspected. Immunohistochemical analysis may be helpful in confirming this diagnosis.

scholarly journals Trial of a Rare Diagnosis in a Core Needle Biopsy of Breast

2021 ◽  
Vol 14 ◽  
pp. 2632010X2110492
Author(s):  
Karima Idrissi Serhrouchni ◽  
Jinane Kharmoum ◽  
Mariame Chraibi ◽  
Ouafae karmouni ◽  
Fayrouz Rabhi ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Mucinous Carcinoma ◽  
Left Breast ◽  
Good Prognosis ◽  
Pathological Examination ◽  
Biopsy Material ◽  
Core Needle ◽  
Benign Process

Objective: Mucinous carcinoma is a rare, special subtype of breast carcinoma associated with a good prognosis. It often presents a confusing appearance with a benign process. For all these reasons, differential diagnosis could be challenging. Case Report: Eighty years-old woman with a soft, lobulated, and well circumscribed mass at the left breast mimicking a benign process. Pathological examination of a core needle biopsy showed pure mucinous carcinoma. Discussion: It is a disease of elderly patient, over 60 years, and usually occurs in postmenopausal women. It accounts for only 2% of total breast carcinomas. On pathologic analysis, to be defined as pure mucinous carcinoma, a carcinoma must be made up of at least 90% intracellular or extracellular mucin. Conclusion: Examination of core biopsy material should be done carefully respecting this criteria to confirm the diagnosis of this rare entity and eliminate differential diagnosis.

Predicting the biologic classification of phyllodes tumors from preoperative core needle biopsy and imaging findings.

2014 ◽  
Vol 32 (26_suppl) ◽  
pp. 86-86
Author(s):  
Saba Yasir ◽  
Erica L Martin-Macintosh ◽  
Edwin O Onkendi ◽  
Rafael E. Jimenez ◽  
Robert T. Fazzio ◽  
...  
Keyword(s):  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Surgical Excision ◽  
Final Diagnosis ◽  
Tumor Type ◽  
Imaging Findings ◽  
Chi Square ◽  
Core Needle ◽  
Phyllodes Tumors ◽  
Low Sensitivity

86 Background: Phyllodes tumors (PT) are rare breast neoplasms confounding their systematic study and evidence-based management guidelines. There is little data on the sensitivity of preoperative core needle biopsy (CNB) and imaging findings in establishing a correct preoperative diagnosis. We undertook this study to evaluate the sensitivity of CNB histologic findings and imaging findings in preoperatively categorizing tumors as benign or borderline/malignant. Methods: We identified 47 patients who underwent surgical resection of a PT at our institution after a preoperative CNB between 6/2000-3/2012. Statistical analysis utilized Wilcoxon rank-sum, chi-square or Fisher’s exact tests, and 95% confidence intervals (CI) are reported. Results: 30 patients had a final diagnosis of benign and 17 of borderline/malignant PT. The latter were significantly more often palpable (76.5% vs 36.7%, p=0.01). No other clinical or radiologic feature predicted borderline/malignant subtype, although irregular shape on US was suggestive (70.6% vs 44.8%, p= 0.09). CNB diagnosis by tumor type is summarized in the table. No benign PT had ≥10 mitoses, necrosis or marked stromal atypia on CNB. No case with absent mitoses on preoperative CNB was a borderline/malignant PT; however 77% of benign PT did exhibit mitoses on CNB. Sensitivity of CNB for PT overall was 48.9% (95% CI: 35.3-62.8%) while it was 40% (24.6-57.7%) for benign PT and 17.6% (6.2-41.0%) for borderline/malignant PT. Conclusions: Marked stromal atypia, ≥10 mitoses and necrosis were rare on CNB, but suggestive of malignancy. No imaging or histology feature reliably distinguished between tumor types. Over one-third of borderline/malignant PT had a preoperative CNB diagnosis of fibroadenoma or cellular fibroepithelial lesion emphasizing the low sensitivity of CNB and the need for judicious consideration of definitive surgical excision. [Table: see text]

Lymphoepithelioma-like Carcinoma of the Breast: Diagnosis by Core Needle Biopsy

2009 ◽  
Vol 15 (6) ◽  
pp. 658-660 ◽  
Author(s):  
Emerald O’Sullivan-Mejia ◽  
Michael O. Idowu ◽  
H. Davis Masssey ◽  
Gilda Cardenosa ◽  
Margaret M. Grimes
Keyword(s):  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Carcinoma Of The Breast ◽  
Core Needle

scholarly journals Invasive Pleomorphic-Type Lobular Carcinoma of the Breast Presenting as a Mucinous Carcinoma

2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
A. Baig ◽  
G. Omeroglu-Altinel ◽  
A. Omeroglu
Keyword(s):  
Needle Biopsy ◽  
Invasive Carcinoma ◽  
Lobular Carcinoma ◽  
Mucinous Carcinoma ◽  
Unique Case ◽  
Carcinoma Of The Breast ◽  
Core Needle ◽  
Mucin Production ◽  
Solid Papillary Carcinoma ◽  
The Impact

Invasive mucinous carcinoma of the breast is mostly associated with invasive carcinoma of no special type (NST) and sometimes with neuroendocrine type tumors such as solid papillary carcinoma. Extracellular mucin production in invasive lobular carcinoma (ILC) is extremely rare. To the best of our knowledge only 18 such cases have been described in the literature. Here we present a unique case of invasive pleomorphic-type lobular carcinoma (IPTLC) presenting as a mucinous carcinoma of the breast on core needle biopsy. Here we discuss the impact and ways to suspect such case.

Intracystic papillary carcinoma of the breast in a male patient diagnosed by core needle biopsy: a case report

The Breast ◽  
2005 ◽  
Vol 14 (4) ◽  
pp. 322-324 ◽  
Author(s):  
Takayuki Kinoshita ◽  
Takashi Fukutomi ◽  
Eriko Iwamoto ◽  
Miyuki Takasugi ◽  
Sadako Akashi-Tanaka ◽  
...  
Keyword(s):  
Case Report ◽  
Papillary Carcinoma ◽  
Male Patient ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Carcinoma Of The Breast ◽  
Core Needle ◽  
Intracystic Papillary Carcinoma
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