The significance of accurate diagnosis of encapsulated papillary carcinoma of the breast by core needle biopsy

2021 ◽  
Vol 27 (3) ◽  
pp. 207-208
Author(s):  
Shahla Masood
The Breast ◽  
2005 ◽  
Vol 14 (4) ◽  
pp. 322-324 ◽  
Author(s):  
Takayuki Kinoshita ◽  
Takashi Fukutomi ◽  
Eriko Iwamoto ◽  
Miyuki Takasugi ◽  
Sadako Akashi-Tanaka ◽  
...  

2020 ◽  
Vol 2 (6) ◽  
pp. 590-597
Author(s):  
Sarah E Bonnet ◽  
Gloria J Carter ◽  
Wendie A Berg

Abstract Encapsulated papillary carcinoma (EPC) is a rare, clinically indolent breast malignancy most common in postmenopausal women. Absence of myoepithelial cells at the periphery is a characteristic feature. Mammographically, EPC typically presents as a mostly circumscribed, noncalcified, dense mass that can have focally indistinct margins when there is associated frank invasive carcinoma. Ultrasound shows a circumscribed solid or complex cystic and solid mass, and occasional hemorrhage in the cystic component may produce a fluid-debris level; the solid components typically show intense washout enhancement on MRI. Color Doppler may demonstrate a prominent vascular pedicle and blood flow within solid papillary fronds. Encapsulated papillary carcinoma can exist in pure form; however, EPC is often associated with conventional ductal carcinoma in-situ and/or invasive ductal carcinoma, no special type. Adjacent in-situ and invasive disease may be only focally present at the periphery of EPC and potentially unsampled at core-needle biopsy. In order to facilitate diagnosis, the mass wall should be included on core-needle biopsy, which will show absence of myoepithelial markers. Staging and prognosis are determined by any associated frankly invasive component, with usually excellent long-term survival and rare distant metastases.


2019 ◽  
Vol 6 (4) ◽  
pp. 265
Author(s):  
ArunK Kumar ◽  
Prita Pradhan ◽  
Saranya Mohan ◽  
Debasis Gochhait ◽  
PampaChi Toi ◽  
...  

2006 ◽  
Vol 94 (1) ◽  
pp. 21-27 ◽  
Author(s):  
Goro Mitsuyoshi ◽  
Noriko Naito ◽  
Akira Kawai ◽  
Toshiyuki Kunisada ◽  
Aki Yoshida ◽  
...  

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Daiki Takatsuka ◽  
Hiroyuki Ogura ◽  
Yuko Asano ◽  
Akiko Nakamura ◽  
Kei Koizumi ◽  
...  

Abstract Background Fibromatosis-like metaplastic carcinoma (FLMCa), classified as a metaplastic carcinoma of the breast, is a very rare type of metaplastic carcinoma. We report a case of FLMCa that was difficult to diagnose. Case presentation The patient was a 56-year-old postmenopausal woman who presented with a left-sided breast mass. A 1.3-cm irregular mass was found in the lower outer quadrant of the left breast on breast ultrasonography. She underwent core needle biopsy and vacuum-assisted biopsy, but the pathological findings only revealed inflammatory cell infiltration and a high level of fibrosis, with no malignant findings. At 3 months follow-up, she underwent a repeat breast ultrasonography, which revealed an increase in the size of the mass to 1.8 cm, and a repeat core needle biopsy, which showed a few spindle cells and squamous cells positive for cytokeratin (CK)5/6 and AE1/AE3, leading to the suspicion of FLMCa. Since the amount of tissue was insufficient to establish a definitive diagnosis, she underwent a lumpectomy. We found low-grade and slightly atypical spindle cells and partly atypical spindle cell carcinoma and squamous cell carcinoma. CK5/6 and α-SMA were positive, thus confirming FLMCa. Because the margins on the edge of the nipple side and anterior side were “ink on tumor”, she underwent a mastectomy and sentinel lymph node biopsy. After the surgery, she received adjuvant chemotherapy. At 3 years and 8 months of follow-up, no recurrent or metastatic lesions were identified in her body. Conclusions FLMCa should be considered in the differential diagnosis when collagenous fibers are proliferating and malignancy is clinically suspected. Immunohistochemical analysis may be helpful in confirming this diagnosis.


2012 ◽  
Vol 126 (4) ◽  
pp. 391-394 ◽  
Author(s):  
R Salzman ◽  
M A Buchanan ◽  
L Berman ◽  
P Jani

AbstractIntroduction:Intramuscular haemangiomas of the digastric muscle are often misdiagnosed due to their low incidence and non-specific manifestation. Only two out of six previously reported cases were diagnosed correctly before excision. Ultrasound may not reveal their vascularity, and fine-needle aspiration biopsy is unhelpful as it reveals only blood.Methods:A case of intramuscular haemangioma of the posterior belly of the digastric muscle is described. Previously reported cases are reviewed. Investigations used to diagnose the lesions and reasons for their common failure are discussed.Results:Core-needle biopsy led to the correct histological diagnosis, and magnetic resonance imaging precisely located the lesion within the digastric muscle.Conclusion:Core-needle biopsy was safely used in the diagnosis of an intramuscular haemangioma. The combination of core-needle biopsy and meticulous review of magnetic resonance imaging enables accurate diagnosis pre-operatively.


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