Letter: A Simple Ion Source Set-up for Desorption/Ionization on Silicon with Ion Mobility Spectrometry and Ion Mobility Spectrometry-Mass Spectrometry

2011 ◽  
Vol 17 (6) ◽  
pp. 593-597 ◽  
Author(s):  
Alexey Adamov ◽  
Alexey A. Sysoev ◽  
Kestutis Grigoras ◽  
Jaakko Laakia ◽  
Tapio Kotiaho
Keyword(s):  
Mass Spectrometry ◽  
Ion Mobility Spectrometry ◽  
Ion Mobility ◽  
Ion Source ◽  
Desorption Ionization ◽  
Set Up

Ion mobility spectrometry-mass spectrometry examination of the structures, stabilities, and extents of hydration of dimethylamine–sulfuric acid clusters

2016 ◽  
Vol 18 (33) ◽  
pp. 22962-22972 ◽  
Author(s):  
Jikku M. Thomas ◽  
Siqin He ◽  
Carlos Larriba-Andaluz ◽  
Joseph W. DePalma ◽  
Murray V. Johnston ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Sulfuric Acid ◽  
Mass Spectrometer ◽  
Ion Mobility Spectrometry ◽  
Ion Mobility ◽  
Atmospheric Pressure ◽  
P Uptake ◽  
Ion Source ◽  
Cluster Ions ◽  
Water Molecules

Uptake of water molecules by dimethylamine–sulfuric acid cluster ions mitigates dissociation in atmospheric pressure ion source mass spectrometer inlets.

scholarly journals Use of Cyclic Ion Mobility Spectrometry (cIM)-Mass Spectrometry to Study the Intramolecular Transacylation of Diclofenac Acyl Glucuronide

2021 ◽  
Author(s):  
David Higton ◽  
Martin E. Palmer ◽  
Johannes P. C. Vissers ◽  
Lauren G. Mullin ◽  
Robert S. Plumb ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Ion Mobility Spectrometry ◽  
Ion Mobility ◽  
Acyl Glucuronide

scholarly journals Ion Mobility–Mass Spectrometry for Bioanalysis

Separations ◽  
2021 ◽  
Vol 8 (3) ◽  
pp. 33
Author(s):  
Xavier Garcia ◽  
Maria del Mar Sabaté ◽  
Jorge Aubets ◽  
Josep Maria Jansat ◽  
Sonia Sentellas
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Ion Mobility Spectrometry ◽  
Ion Mobility ◽  
Biological Samples ◽  
Ion Mobility Mass Spectrometry ◽  
Exogenous Compounds ◽  
Analytical Separation

This paper aims to cover the main strategies based on ion mobility spectrometry (IMS) for the analysis of biological samples. The determination of endogenous and exogenous compounds in such samples is important for the understanding of the health status of individuals. For this reason, the development of new approaches that can be complementary to the ones already established (mainly based on liquid chromatography coupled to mass spectrometry) is welcomed. In this regard, ion mobility spectrometry has appeared in the analytical scenario as a powerful technique for the separation and characterization of compounds based on their mobility. IMS has been used in several areas taking advantage of its orthogonality with other analytical separation techniques, such as liquid chromatography, gas chromatography, capillary electrophoresis, or supercritical fluid chromatography. Bioanalysis is not one of the areas where IMS has been more extensively applied. However, over the last years, the interest in using this approach for the analysis of biological samples has clearly increased. This paper introduces the reader to the principles controlling the separation in IMS and reviews recent applications using this technique in the field of bioanalysis.

scholarly journals Rapid determination of N-methylpyrrolidine in cefepime by combining direct infusion electrospray ionisation-time-of-flight mass spectrometry with field asymmetric waveform ion mobility spectrometry

2015 ◽  
Vol 7 (1) ◽  
pp. 34-39 ◽  
Author(s):  
Robert W. Smith ◽  
Lisa B. Cox ◽  
Aswandi Yudin ◽  
James C. Reynolds ◽  
Mark Powell ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Ion Mobility Spectrometry ◽  
Ion Mobility ◽  
Rapid Determination ◽  
Time Of Flight ◽  
Asymmetric Waveform ◽  
Direct Infusion ◽  
Electrospray Ionisation ◽  
Flight Mass Spectrometry

FAIMS separation prior to mass spectrometry enables selective transmission of NMP in cefepime without interference from NMP formed by in-source CID.

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