scholarly journals Reversal of Resistance to Doxorubicin with Cepharanthme in Murine P388 Leukemia Cells

1990 ◽  
Vol 54 (4) ◽  
pp. 464-467 ◽  
Author(s):  
Tsutomu FUJIMURA ◽  
Hironobu SHIBATA ◽  
Itoko MAEKAWA ◽  
Shinobu FURUSAWA ◽  
Hiroaki KAWAUCHI ◽  
...  
Keyword(s):  
Leukemia Cells ◽  
P388 Leukemia ◽  
Resistance To Doxorubicin

Cross resistance to cytostatics of P388 leukemia cells with induced resistance to doxorubicin

1993 ◽  
Vol 116 (3) ◽  
pp. 1153-1155
Author(s):  
F. V. Donenko ◽  
S. M. Sitdikova ◽  
A. O. Kabieva ◽  
L. V. Moroz
Keyword(s):  
Induced Resistance ◽  
Leukemia Cells ◽  
Cross Resistance ◽  
P388 Leukemia ◽  
Resistance To Doxorubicin

Comparison of uptake of mitomycin C and KW-2149 by murine P388 leukemia cells sensitive or resistant to mitomycin C

1993 ◽  
Vol 32 (1) ◽  
pp. 20-24 ◽  
Author(s):  
Eiji Kobayashi ◽  
Masami Okabe ◽  
Motomichi Kono ◽  
Hitoshi Arai ◽  
Masaji Kasai ◽  
...  
Keyword(s):  
Mitomycin C ◽  
Leukemia Cells ◽  
P388 Leukemia

Polyamine Metabolism in P388 Leukemia Cells and in Ascites Tumor-Bearing Mice

Pathobiology ◽  
1984 ◽  
Vol 52 (5) ◽  
pp. 279-285 ◽  
Author(s):  
T. Kremmer ◽  
L. Selmeci ◽  
Susan Bardócz ◽  
L. Holczinger ◽  
Susan Bálint
Keyword(s):  
Leukemia Cells ◽  
Polyamine Metabolism ◽  
Ascites Tumor ◽  
P388 Leukemia ◽  
Tumor Bearing

scholarly journals Oxidation and Acetylation of Ursolic and Oleanolic Acids Isolated from Fragraea fragrans fruits; Antiproliferation of P388 Leukemia Cells

2014 ◽  
Vol 14 (3) ◽  
pp. 269-276 ◽  
Author(s):  
Dasril Basir ◽  
Julinar Julinar ◽  
Eva Agustriana ◽  
Budi Untari
Keyword(s):  
Cell Growth ◽  
Natural Product ◽  
Ursolic Acid ◽  
Oleanolic Acid ◽  
Leukemia Cell ◽  
Leukemia Cells ◽  
P388 Leukemia ◽  
Continuous Work ◽  
Cell Proliferations ◽  
Product Chemistry

An interesting natural product chemistry aspect of Fragraea fragrans is that their fruits are richness with ursolic acid and its isomer oleanolic acid (3.05% of dried powder). As our continuous work on these inseparable structural isomeric triterpenes, this paper reports that 51.0% of inseparable 3-oxo-ursolic[3-oxo-oleanolic] acids and 48.6% of inseparable 3-acethyl-ursolic [3-acethyl-oleanolic] acids have already been made from those triterpenes as starting materials of the oxidized and acetylated compounds and evaluated their activity against P388 leukemia cells. The activity of 3-oxo-ursolic [3-oxo-oleanolic] acids with IC50 = 18.6 µg/mL exhibited three-fold more potent against P388 leukemia cell proliferations compared to ursolic [oleanolic] acids with IC50 = 53.5 µg/mL; while the 3-acethyl-ursolic [3-acethyl-oleanolic] acids with IC50 = 37.9 µg/mL showed two-fold more potent then their parent triterpenes (IC50 = 53.5 µg/mL) in the inhibition of P388 leukemia cell growth.

Changes in the Polyamine and Nucleotide Metabolism of P388 Leukemia Cells Treated with DL-α-Difluoromethylornithine in Culture

Pathobiology ◽  
1988 ◽  
Vol 56 (3) ◽  
pp. 131-137 ◽  
Author(s):  
T. Kremmer ◽  
I. Pályi ◽  
L. Holczinger ◽  
I. Lörincz ◽  
M. Boldizsár ◽  
...  
Keyword(s):  
Nucleotide Metabolism ◽  
Leukemia Cells ◽  
P388 Leukemia

Induction of functional Fc receptors in P388 leukemia cells

1985 ◽  
Vol 157 (2) ◽  
pp. 511-519 ◽  
Author(s):  
Donald A. Cohen ◽  
N.Lynn Stotelmyer ◽  
Alan M. Kaplan
Keyword(s):  
Fc Receptors ◽  
Leukemia Cells ◽  
P388 Leukemia
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