scholarly journals Cardiotonic and Coronary Vasodilatatory Effects of Amrinone in the Canine Heart-Lung Preparation with a Support Dog as Compared with Those of Dobutamine

1986 ◽  
Vol 40 (3) ◽  
pp. 381-387 ◽  
Author(s):  
Keisuke TAKEDA ◽  
Kazuki MATSUI ◽  
Mikio NAKAZAWA ◽  
Hajime NAKAHARA ◽  
Hirohisa IMAI ◽  
...  
1984 ◽  
Vol 34 (2) ◽  
pp. 351-355 ◽  
Author(s):  
Shozo KOYAMA ◽  
Nobuyuki TERADA ◽  
Yumiko SHIOJIMA ◽  
Toru TAKEUCHI

1984 ◽  
Vol 36 ◽  
pp. 264
Author(s):  
Motoshi Kainuma ◽  
Itaru Ichimura ◽  
Naohisa Ishikawa ◽  
Tatsuro Shigei.

1977 ◽  
Vol 73 (4) ◽  
pp. 411-421 ◽  
Author(s):  
Yoshito NAKAGAWA ◽  
Keisuke TAKEDA ◽  
Yumi KATANO ◽  
Tokumasa TSUKADA ◽  
Issei MATSUBARA ◽  
...  

1955 ◽  
Vol 3 (1) ◽  
pp. 32-38 ◽  
Author(s):  
E. ROTHLIN ◽  
M. TAESCHLER ◽  
A. CERLETTI

1961 ◽  
Vol 16 (1) ◽  
pp. 186-190
Author(s):  
William L. Sheehan ◽  
William B. Kinzie ◽  
Kenneth L. Westbrook ◽  
William A. Spencer ◽  
Hebbel E. Hoff

Five isolated canine heart-lung preparations were successfully ventilated with intermittent negative pressure in a specially constructed chamber. Improved cardiopulmonary dynamics resulted in increased survival time and improved performance of all preparations. Results obtained with these preparations exceed most of the others reported in the literature. Submitted on May 9, 1960


1988 ◽  
Vol 65 (3) ◽  
pp. 1244-1250 ◽  
Author(s):  
H. E. Fessler ◽  
R. G. Brower ◽  
R. A. Wise ◽  
S. Permutt

To investigate the mechanism by which increased pleural pressure (Ppl) assists left ventricular (LV) ejection, we compared the effects of phasic systolic or diastolic increases in Ppl (40-60 mmHg) with use of an isolated canine heart-lung preparation with constant venous return. Positive Ppl during systole (S) caused left atrial transmural pressure (Platm = Pla - Ppl) to decrease by 1.25 +/- 0.46 (SE) mmHg (P less than 0.025). Central blood volume (CBV), the volume of blood in the heart, lungs, and thoracic great vessels, decreased by 29 +/- 4.0 (SE) ml (P less than 0.001). When Ppl was raised for an equal duration during diastole (D), the decrease in Platm was not significant, but there was a significant decrease in CBV (10.5 +/- 4.1 ml, P less than 0.05). With constant venous return, these changes suggested that phasic elevations in Ppl in either S or D assisted LV ejection by decreasing LV afterload. To test the hypothesis that positive Ppl during D reduced afterload by emptying the thoracic aorta, we compared the effects of diastolic positive Ppl with a rigid aorta vs. a compliant aorta. Although there was no statistical difference in the effects of diastolic positive Ppl on Platm, the decrease in CBV was significantly greater when the aorta was compliant than when it was rigid (23 +/- 2.2 vs. 17 +/- 2.7 ml, P less than 0.05).(ABSTRACT TRUNCATED AT 250 WORDS)


Circulation ◽  
1996 ◽  
Vol 93 (7) ◽  
pp. 1459-1463 ◽  
Author(s):  
Micheal A. Kuhn ◽  
Larry A. Latson ◽  
John P. Cheatham ◽  
Bruce McManus ◽  
James M. Anderson ◽  
...  

Circulation ◽  
1997 ◽  
Vol 95 (2) ◽  
pp. 415-422 ◽  
Author(s):  
Lawrence H. Young ◽  
Yin Renfu ◽  
Raymond Russell ◽  
Xiaoyue Hu ◽  
Michael Caplan ◽  
...  

Circulation ◽  
1995 ◽  
Vol 91 (11) ◽  
pp. 2824-2833 ◽  
Author(s):  
Susan F. Steinberg ◽  
HongLu Zhang ◽  
Elena Pak ◽  
Geraldine Pagnotta ◽  
Penelope A. Boyden

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