scholarly journals UPTAKE AND STORAGE MECHANISM OF 5-HYDRO-XYTRYPTAMINE IN RABBIT BRAIN STEM AND EFFECT OF RESERPINE

1971 ◽  
Vol 21 (1) ◽  
pp. 57-67 ◽  
Author(s):  
Katsuya TAKATSUKA ◽  
Tomio SEGAWA ◽  
Hiroshi TAKAGI
1979 ◽  
Vol 187 (1) ◽  
pp. 199-243 ◽  
Author(s):  
David L. Felten ◽  
John P. Cummings

1997 ◽  
Vol 7 (6) ◽  
pp. 441-451
Author(s):  
J. Kröller ◽  
F. Behrens ◽  
V.V. Marlinsky

Experiments in two awake untrained squirrel monkeys were performed to study the velocity storage mechanism during fast rise of OKN slow phase velocity. This was done by testing the monkey’s capability to perform OKN in response to a stationary-appearing stroboscopically illuminated stripe pattern of a horizontally rotating drum. Nystagmus was initially elicited during constant illumination lasting between 0.6 and 25 s. The periodicity of the stripe pattern was 2.37°. When after the constant light the flash illumination was switched on again, two types of behavior could occur, depending on the length of the constant light interval (CLI): 1) when the CLI was shorter than a threshold value of 6.2 seconds, the OKN ceased under the flash stimulation. Then a “post-OKN” occurred that increased with the length of the CLIs, indicating that the intermittently illuminated pattern did not provoke fixation suppression of OKN aftereffects. 2) when the CLI was above threshold, the OKN continued under the flash light: it will he called “apparent movement OKN.” The threshold CLI between the type 1 and the type 2 response did not depend on drum velocities between 21.5°/s and 71.3°/s. The average gain of the apparent movement OKN was 0.83 ± 0.04; gain and stability of slow phase eye movement velocity did not deviate systematically from the usually elicited OKN. OKAN after apparent movement OKN did not deviate from OKAN after constantly illuminated moving patterns. In response to the OKN initiation by a constantly illuminated pattern up to pattern velocities of 100°/s, the OKN steady state gain was reached within the first 2 or 3 nystagmus beats. We ascribe the increase of the post-OKN with CLI and the existence of a threshold constant light interval to activity-accumulation in the common velocity-to-position integrator (velocity storage) of the brain stem. Loading of the velocity storage takes place after the OKN gain has already reached the steady-state value. Apparent movement OKN could also be elicited in guinea pigs that lack an effective smooth pursuit system. We suggest that apparent movement OKN is produced by mechanisms located in the brain stem.


2016 ◽  
Vol 64 ◽  
pp. 51-59 ◽  
Author(s):  
Bobo Cao ◽  
Shuangyue Liu ◽  
Dongmei Du ◽  
Zhimin Xue ◽  
Hui Fu ◽  
...  

1967 ◽  
Vol 19 (6) ◽  
pp. 345-349 ◽  
Author(s):  
A. DAHLSTRÖM ◽  
K. FUXE ◽  
B. HAMBERGER ◽  
T. HÖKFELT

1955 ◽  
Vol 32 (1) ◽  
pp. 84-94
Author(s):  
B. W. STADDON

1. A study has been made of the excretion and storage of ammonia by the aquatic larva of Sialis lutaria. 2. About 90% of the nitrogen excreted by the larva of Sialis during starvation was in the form of ammonia. The daily ammonia output averaged 10 µg. N/100 mg. wet weight. 3. Ammonia was found to be excreted into the hindgut, presumably via the Malpighian tubules. The concentration of ammonia in the hindgut fluid averaged 136 mg. N/100 ml. 4. Evidence was obtained that the tissue fluids are not maintained completely ammonia-free. Thus the total ammonia content of the body averaged 1.0 µg. N/100 mg. wet weight of tissue. The concentration of ammonia in the haemolymph averaged 0.50 mg. N/100 ml. 5. Evidence was obtained that the larval tissues are capable of ‘storing’ appreciable quantities of ammonia. Thus ammonia did not accumulate in the tissue fluids of larvae prevented from excreting for a period of days. Furthermore, it was found experimentally possible to raise the concentration of ammonia in the tissue fluids, the ammonia subsequently disappearing. The possible significance of this ‘storage’ mechanism was discussed. 6. The method used for raising the concentration of ammonia in the tissue fluids, by immersing the larva for some time in a solution of dilute ammonia, was considered in some detail, particularly with respect to toxic effects. When the concentration of ammonia in the haemolymph had reached a level in the region of 7.0 mg. N/100 ml. toxic symptoms started to appear.


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