scholarly journals MECHANISM OF HISTAMINE-RELEASE INHIBITION BY NICOTINAMIDE IN IN VITRO ANTIGEN-ANTIBODY REACTION

1962 ◽  
Vol 11 (1) ◽  
pp. 54-64 ◽  
Author(s):  
HIDEMASA YAMASAKI ◽  
SABURO MURAOKA ◽  
MIE SUGIYAMA ◽  
KOITI ENDO
Keyword(s):  
Histamine Release ◽  
Antibody Reaction ◽  
Antigen Antibody

Independence of activation of the fibrinolytic system from certain immunologic systems

1959 ◽  
Vol 196 (2) ◽  
pp. 431-435 ◽  
Author(s):  
S. N. Kolmen ◽  
D. R. Celander ◽  
M. Mason Guest
Keyword(s):  
Fibrinolytic Activity ◽  
Complement Fixation ◽  
Fibrinolytic System ◽  
Complement Activity ◽  
Antibody Reaction ◽  
Antigen Antibody

Activation of the immunologic system either in vitro or in vivo results in nearly complete consumption of complement without activation of the fibrinolytic system. However complement activity decreased upon the induction of fibrinolytic activity even in the absence of an antigen-antibody reaction. Presumably this is due to proteolysis of some part of the complement complex since complement activity was found to be destroyed in the presence of small quantities of purified fibrinolysin. These observations are consistent with the conclusion that a) the components of complement and those of the fibrinolytic system are separate and discrete entities; b) that reactions involving complement fixation and activation do not directly influence the fibrinolytic system; and c) that activation of the fibrinolytic system results in decreases in complement through proteolysis of one or more of its components by the fibrinolysin which develops.

scholarly journals Inhibitory Effects of (4-Alkoxy-2,3,6-trimethylphenyl)glycopyranosides on Histamine Release Induced by Antigen-Antibody Reaction.

1994 ◽  
Vol 42 (4) ◽  
pp. 1002-1004
Author(s):  
Tzer Chuan WANG ◽  
Hisao KAKEGAWA ◽  
Shigeru NAKAISHI ◽  
Hitoshi MATSUMOTO ◽  
Toshio SATOH
Keyword(s):  
Histamine Release ◽  
Inhibitory Effects ◽  
Antibody Reaction ◽  
Antigen Antibody

scholarly journals Leukocyte Antigen-Antibody Reaction and Lysis of Paroxysmal Nocturnal Hemoglobinuria Erythrocytes

Blood ◽  
1970 ◽  
Vol 36 (3) ◽  
pp. 334-336 ◽  
Author(s):  
GIROLAMO SIRCHIA ◽  
SOLDANO FERRONE ◽  
FRANCESCO MERCURIALI
Keyword(s):  
Paroxysmal Nocturnal Hemoglobinuria ◽  
Cell Lysis ◽  
Red Cells ◽  
Clinical Implications ◽  
Specific Antibodies ◽  
Leukocyte Antigen ◽  
Leukocyte Antigens ◽  
Antibody Reaction ◽  
Antigen Antibody

Abstract The interaction between leukocyte antigens and specific antibodies can cause lysis of the red cells of paroxysmal nocturnal hemoglobinuria (PNH) in vitro. It is suggested that the activation of complement ensuing from the antigen-antibody interaction is responsible for PNH cell lysis. The clinical implications of this finding are briefly outlined.

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