scholarly journals Effects of a new psychotropic agent, CS-430, on the central nervous system of experimental animals.

1978 ◽  
Vol 74 (7) ◽  
pp. 857-870
Author(s):  
Nobuyoshi IWATA ◽  
Kazuo KOBAYASHI ◽  
Takao HARA ◽  
Masako MATSUMURA ◽  
Naoji Mikuni ◽  
...  
PEDIATRICS ◽  
1982 ◽  
Vol 69 (1) ◽  
pp. 129-129
Author(s):  
John M. Graham

In general, I agree with the comments expressed above. We did not intend to imply that the pattern of neuromotor dysfunction was in any way specific to gestational hyperthermia. What we find provocative about our study is that the timing of gestational hyperthermia in the human, and the defects associated with such hyperthermia, are very similar to the timing and defects which are seen in experimental animals. In fact, the studies by Edwards (cited in our paper) would appear to suggest that the predominant effect of prolonged hyperthermia during early pregnancy is on the central nervous system.


Parasitology ◽  
1999 ◽  
Vol 119 (6) ◽  
pp. 577-581 ◽  
Author(s):  
P. HORÁK ◽  
J. DVOŘÁK ◽  
L. KOLÁŘOVÁ ◽  
L. TREFIL

The development of nasal avian schistosomes of the genus Trichobilharzia in their final host is poorly known. Therefore, an experimental infection of ducklings (Anas platyrhynchos f. dom.) by T. regenti was performed. The infection resulted in leg paralysis and orientation/balance disorders of birds. The examination of the duck's spinal cord and brain confirmed the presence of developing parasites in pre-patent as well as patent periods. The absence of the worms in other tissues strongly supports our hypothesis that the parasite migrates through the central nervous system (CNS) to its final location in bird nasal mucosa. The injury level is probably dependent on number of parasites as well as yet unknown host factors. The affinity to the CNS seems to be high; also by exposure of experimental animals to low cercarial doses the growing worms in the CNS were found. In addition to the generally accepted view that bird schistosomes may cause cercarial dermatitis of mammals (including man), there is evidence of a partial development of T. regenti in mouse CNS; in certain cases leg paralysis was also recorded. Therefore, the pathogenesis spectrum caused by bird schistosomes in birds/mammals needs to be reconsidered.


1981 ◽  
Vol 31 (3) ◽  
pp. 391-400
Author(s):  
Yukiko SUZUKI ◽  
Yukihiko HAGIWARA ◽  
Kyoji TAGUCHI ◽  
Kazuyo KAJIYAMA ◽  
Takato IKEDA

NeuroRx ◽  
2005 ◽  
Vol 2 (2) ◽  
pp. 250-264 ◽  
Author(s):  
Istvan Pirko ◽  
Stanley Thomas Fricke ◽  
Aaron J. Johnson ◽  
Moses Rodriguez ◽  
Slobodan I. Macura

1989 ◽  
Vol 17 (6) ◽  
pp. 539-546 ◽  
Author(s):  
J. P. Belon ◽  
M. Orosco ◽  
J. C. Henry ◽  
C. Jacquot

Regulation of blood glucose involves the integration of the central nervous system with both hormonal and neural mechanisms. Considerable evidence suggests that β-endorphin is involved in the regulation of feeding in experimental animals and man. Previous studies have shown that β-endorphin plays an important role during hypergiycaemia. Glipizide has been shown to increase glucose metabolism by both pancreatic and extrapancreatic actions. This study indicates that glipizide may exert its pharmacological action in obese cafeteria rats through a modification of β-endorphin secretions via central and peripheral mechanisms.


Author(s):  
Veronika Makarova ◽  
Konstantin Usov

Evaluation of the effect of isopropyl methacarborane on the central nervous system with repeated inhalation in experimental animals was carried out.


2005 ◽  
Vol 2 (2) ◽  
pp. 250-264
Author(s):  
Istvan Pirko ◽  
Stanley Thomas Fricke ◽  
Aaron J. Johnson ◽  
Moses Rodriguez ◽  
Slobodan I. Macura

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