scholarly journals Effects of lithium chloride administered in combination with methamphetamine or a reserpine-like drug on brain norepinephrine and dopamine metabolism in rats

1976 ◽  
Vol 72 (6) ◽  
pp. 715-723 ◽  
Author(s):  
Takashi NOZU ◽  
Tatsuo FURUKAWA
Keyword(s):  
Lithium Chloride ◽  
Dopamine Metabolism ◽  
Brain Norepinephrine

C-fos Expression in the Brain Following Lithium Chloride Induced-Illness

2006 ◽  
Author(s):  
Katie M. Albanos ◽  
Steve Reilly ◽  
Justin R. St. Andre
Keyword(s):  
Lithium Chloride ◽  
Fos Expression ◽  
The Brain

Noncataleptic neuroleptic agents: Synthesis of some esters of 2-chloro-10-(4-(2-hydroxyethyl)piperazino)-10,11-dihydrodibenzo[b,f]thiepin

1986 ◽  
Vol 51 (7) ◽  
pp. 1503-1508
Author(s):  
Jiří Jílek ◽  
Martin Valchář ◽  
Josef Pomykáček ◽  
Antonín Dlabač ◽  
Miroslav Protiva
Keyword(s):  
Rat Brain ◽  
Succinic Anhydride ◽  
Dopamine Metabolism ◽  
Low Doses ◽  
Brain Striatum

Reactions of 2-chloro-10-(4-(2-hydroxyethyl)piperazino)-10,11-dihydrodibenzo[b,f]thiepin (I) with phenylacetic, methoxyacetic, methylthioacetic, phenoxyacetic and morpholinoacetic acid in dichloromethane and in the presence of N,N'-carbonyldiimidazole gave the title esters II - VI. Reaction of I with succinic anhydride afforded the hemisuccinate VII. The esters prepared elicited ataxia in low doses, were low-cataleptic, but only II, IV, and VII proved some antidopaminergic activity in the test using the affecting dopamine metabolism in rat brain striatum.

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