scholarly journals Afferent nerve activity in relation to bladder sensation

2019 ◽  
Vol 154 (5) ◽  
pp. 255-258
Author(s):  
Naoki Aizawa
1999 ◽  
Vol 276 (6) ◽  
pp. R1819-R1824
Author(s):  
Els van Asselt ◽  
Joost le Feber ◽  
Ron van Mastrigt

In this study, the mechanism involved in the initiation of voiding was investigated. Bladder pressure and bladder and urethral nerve activity were recorded in the anesthetized rat. Bladder nerve activity was resolved into afferent and efferent activity by means of a theoretical model. The beginning of an active bladder contraction was defined as the onset of bladder efferent firing at a certain time ( t 0). From t 0 onward, bladder efferent activity increased linearly during δ t seconds (rise time) to a maximum. The pressure at t 0 was 1.0 ± 0.4 kPa, the afferent nerve activity at t 0 was 2.0 ± 0.6 μV (53 ± 15% of maximum total nerve activity), and δ t was 11 ± 13 s. Between contractions the afferent activity at t 0 was never exceeded. Urethral afferent nerve activity started at bladder pressures of 2.1 ± 1.1 kPa. Therefore, we concluded that urethral afferent nerve activity does not play a role in the initiation of bladder contractions; voiding contractions presumably are initiated by bladder afferent nerve activity exceeding a certain threshold.


1999 ◽  
Vol 162 (1) ◽  
pp. 204-212 ◽  
Author(s):  
SUK YOUNG JUNG ◽  
MATTHEW O. FRASER ◽  
HIDEO OZAWA ◽  
OSAMU YOKOYAMA ◽  
MITSUHARU YOSHIYAMA ◽  
...  

2007 ◽  
Vol 27 (7) ◽  
pp. 1725-1737 ◽  
Author(s):  
E. Erazo-Fischer ◽  
J. Striessnig ◽  
H. Taschenberger

2019 ◽  
Vol 18 (6) ◽  
pp. 1915-1926 ◽  
Author(s):  
Lingxia Bao ◽  
Jingbo Zhao ◽  
Donghua Liao ◽  
Guixue Wang ◽  
Hans Gregersen

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