scholarly journals Influences of febrile seizures on developing neuronal circuits: cellular and molecular approaches using animal models

2010 ◽  
Vol 136 (4) ◽  
pp. 219-224
Author(s):  
Junya Ichikawa ◽  
Norio Matsuki ◽  
Ryuta Koyama
Keyword(s):  
Animal Models ◽  
Febrile Seizures ◽  
Neuronal Circuits ◽  
Molecular Approaches

scholarly journals Update on animal models of diabetic retinopathy: from molecular approaches to mice and higher mammals

2012 ◽  
Vol 5 (4) ◽  
pp. 444-456 ◽  
Author(s):  
R. Robinson ◽  
V. A. Barathi ◽  
S. S. Chaurasia ◽  
T. Y. Wong ◽  
T. S. Kern
Keyword(s):  
Diabetic Retinopathy ◽  
Animal Models ◽  
Molecular Approaches

scholarly journals Febrile Seizures: Current Views and Investigations

2009 ◽  
Vol 36 (6) ◽  
pp. 679-686 ◽  
Author(s):  
Aylin Y. Reid ◽  
Michael A. Galic ◽  
G. Campbell Teskey ◽  
Quentin J. Pittman
Keyword(s):  
Animal Models ◽  
Current Literature ◽  
Growth And Development ◽  
Animal Studies ◽  
Pediatric Population ◽  
Febrile Seizures ◽  
Long Term Effects ◽  
Common Cause ◽  
Increased Risk

Febrile seizures (FSs) are seizures that occur during fever, usually at the time of a cold or flu, and represent the most common cause of seizures in the pediatric population. Up to 5% of children between the ages of six months and five years-of-age will experience a FS. Clinically these seizures are categorized as benign events with little impact on the growth and development of the child. However, studies have linked the occurrence of FSs to an increased risk of developing adult epileptic disorders. There are many unanswered questions about FSs, such as the mechanism of their generation, the long-term effects of these seizures, and their role in epileptogenesis. Answers are beginning to emerge based on results from animal studies. This review summarizes the current literature on animal models of FSs, mechanisms underlying the seizures, and functional, structural, and molecular changes that may result from them.

Molecular Approaches to Human Neurological Diseases and Their Animal Models

1986 ◽  
pp. 171-180 ◽  
Author(s):  
Donald L. Price ◽  
Paul N. Hoffman ◽  
Richard J. Altschuler ◽  
Edward H. M. Koo ◽  
Peter J. Whitehouse ◽  
...  
Keyword(s):  
Animal Models ◽  
Neurological Diseases ◽  
Molecular Approaches

Reductionist thinking and animal models in neuropsychiatric research

2019 ◽  
Vol 42 ◽  
Author(s):  
Nicole M. Baran
Keyword(s):  
Animal Models ◽  
Mental Disorders ◽  
Environmental Factors ◽  
Neuropsychiatric Disorders ◽  
Model Organisms ◽  
Developmental Genetic ◽  
Term Study ◽  
Genetic And Environmental Factors ◽  
Mechanisms Of Plasticity

AbstractReductionist thinking in neuroscience is manifest in the widespread use of animal models of neuropsychiatric disorders. Broader investigations of diverse behaviors in non-model organisms and longer-term study of the mechanisms of plasticity will yield fundamental insights into the neurobiological, developmental, genetic, and environmental factors contributing to the “massively multifactorial system networks” which go awry in mental disorders.

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