scholarly journals Assessment of superior vena caval blood flow velocity in ischemic heart disease.

1991 ◽  
Vol 55 (6) ◽  
pp. 576-580
Author(s):  
KAYOKO MURAI ◽  
HIDETAKA IIDA ◽  
HIROSHI ITAGANE ◽  
KAZUYOSHI HIROTA ◽  
MITSUTAKA YASUDA ◽  
...  
Keyword(s):  
Blood Flow ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Flow Velocity ◽  
Blood Flow Velocity ◽  
Superior Vena ◽  
Ischemic Heart ◽  
Superior Vena Caval

Inverse correlation between coronary blood flow velocity and sICAM-1 level observed in ischemic heart disease patients

2006 ◽  
Vol 188 (1) ◽  
pp. 142-149 ◽  
Author(s):  
Jusztina Bencze ◽  
Robert Gabor Kiss ◽  
Emese Toth-Zsamboki ◽  
Katarina Vargova ◽  
Gabor Kerecsen ◽  
...  
Keyword(s):  
Blood Flow ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Flow Velocity ◽  
Coronary Blood Flow ◽  
Blood Flow Velocity ◽  
Inverse Correlation ◽  
Ischemic Heart ◽  
Coronary Blood Flow Velocity

scholarly journals Physiological Impact of Afterload Reduction on Cardiac Mechanics and Coronary Hemodynamics Following Isosorbide Dinitrate Administration in Ischemic Heart Disease

2021 ◽  
Author(s):  
Tiffany Patterson ◽  
Simone Rivolo ◽  
Daniel Burkhoff ◽  
Jan Schreuder ◽  
Natalia Briceno ◽  
...  
Keyword(s):  
Blood Flow ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Flow Velocity ◽  
Isosorbide Dinitrate ◽  
Blood Flow Velocity ◽  
Inverse Relationship ◽  
Arterial Elastance ◽  
Afterload Reduction ◽  
Coronary Blood Flow Velocity

Abstract Understanding the cardiac-coronary interaction is fundamental to developing treatment strategies for ischemic heart disease. We sought to examine the impact of afterload reduction following isosorbide dinitrate (ISDN) administration on LV properties and coronary hemodynamics to further our understanding of the cardiac-coronary interaction. Novel methodology enabled real-time simultaneous acquisition and analysis of coronary and LV hemodynamics in vivo using coronary pressure-flow wires (used to derive coronary wave energies) and LV pressure-volume loop assessment. ISDN administration resulted in afterload reduction, reduced myocardial demand, and increased mechanical efficiency (all P<0.01). Correlations were demonstrated between the forward compression wave (FCW) and arterial elastance (r=0.6) following ISDN. In the presence of minimal microvascular resistance, coronary blood flow velocity exhibited an inverse relationship with LV elastance. In summary this study demonstrated a reduction in myocardial demand with ISDN, an inverse relationship between coronary blood flow velocity and LV contraction-relaxation and a direct correlation between FCW and arterial elastance. Graphical abstract The pressure volume-loop and corresponding parameters b The pressure volume loop before (solid line) and after (broken line) Isosorbide dintrate

Effect of hyperoxia and vitamin C on coronary blood flow in patients with ischemic heart disease

2007 ◽  
Vol 102 (5) ◽  
pp. 2040-2045 ◽  
Author(s):  
Patrick H. McNulty ◽  
Bryan J. Robertson ◽  
Mark A. Tulli ◽  
Joshua Hess ◽  
Lisa A. Harach ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Blood Flow ◽  
Heart Disease ◽  
Vitamin C ◽  
Ischemic Heart Disease ◽  
Flow Velocity ◽  
Clinical Setting ◽  
Blood Flow Velocity ◽  
Coronary Resistance ◽  
Coronary Tone

Pathological formation of reactive oxygen species within the coronary circulation has been hypothesized to mediate some clinical manifestations of ischemic heart disease (IHD) by interfering with physiological regulation of coronary tone. To determine the degree to which coronary tone responds to acute changes in ambient levels of oxidants and antioxidants in vivo in a clinical setting, we measured the effect of an acute oxidative stress (breathing 100% oxygen) on coronary capacitance artery diameter (quantitative angiography) and blood flow velocity through the coronary microcirculation (intracoronary Doppler ultrasonography) before and after treatment with the antioxidant vitamin C (3-g intravenous infusion) in 12 IHD patients undergoing a clinical coronary interventional procedure. Relative to room air breathing, 100% oxygen breathing promptly reduced coronary blood flow velocity by 20% and increased coronary resistance by 23%, without significantly changing the diameter of capacitance arteries. Vitamin C administration promptly restored coronary flow velocity and resistance to a slightly suprabasal level, and it prevented the reinduction of coronary constriction with rechallenge with 100% oxygen. This suggests that acute oxidative stress produces prompt and substantial changes in coronary resistance and blood flow in a clinical setting in patients with IHD, and it suggests that these changes are mediated by vitamin C-quenchable substances acting on the coronary microcirculation. This observation may have relevance for clinical practice.

Factors affecting regional pulmonary blood flow in chronic ischemic heart disease

1988 ◽  
Vol 3 (3) ◽  
pp. 65-72 ◽  
Author(s):  
Massimo Pistolesi ◽  
Massimo Miniati ◽  
Marisa Bonsignore ◽  
Felicita Andreotti ◽  
Giorgio Di Ricco ◽  
...  
Keyword(s):  
Blood Flow ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Pulmonary Blood Flow ◽  
Ischemic Heart ◽  
Chronic Ischemic Heart Disease ◽  
Factors Affecting
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