scholarly journals Renal denervation inhibits hypothalamo-sympathetic nerve system in normotensive and hypertensive rats.

1985 ◽  
Vol 49 (9) ◽  
pp. 997-1004 ◽  
Author(s):  
KAZUO TAKEDA ◽  
HIROSHI OKAJIMA ◽  
MASAHIRO YOSHIGA ◽  
LI-CHIK LEE ◽  
ISAO IYODA ◽  
...  
1980 ◽  
Vol 44 (5) ◽  
pp. 409-410 ◽  
Author(s):  
KAZUO TAKEDA ◽  
SUSUMU SASAKI ◽  
ISAO KAIMASU ◽  
MINABU YOSHIMURA ◽  
MASAO NAKAGAWA ◽  
...  

2019 ◽  
Vol 189 ◽  
pp. 107828 ◽  
Author(s):  
Joana Raquel Martins ◽  
Nadine Reichhart ◽  
Nobert Kociok ◽  
Julia Stindl ◽  
Renate Foeckler ◽  
...  

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Tao Dong ◽  
Yu-Wen Cheng ◽  
Fei Yang ◽  
Pei-Wen Sun ◽  
Chen-Jie Zhu ◽  
...  

The increasing pressure of modern social life intensifies the impact of stress on the development of cardiovascular diseases, which include deep venous thrombosis (DVT). Renal sympathetic denervation has been applied as one of the clinical approaches for the treatment of drug-resistant hypertension. In addition, the close relationship between oxidative stress and cardiovascular diseases has been well documented. The present study is designed to explore the mechanism by which the renal sympathetic nerve system and the oxidative stress affect the blood coagulation system in the development of DVT. Chronic foot shock model in rats was applied to mimic a state of physiological stress similar to humans. Our results showed that chronic foot shock procedure could promote DVT which may be through the activation of platelets aggregation. The aggravation of DVT and activation of platelets were alleviated by renal sympathetic denervation or antioxidant (Tempol) treatment. Concurrently, the denervation treatment could also reduce the levels of circulating oxidation factors in rats. These results demonstrate that both the renal sympathetic nerve system and the oxidative stress contribute to the development of DVT in response to chronic stress, which may provide novel strategy for treatment of clinic DVT patients.


1986 ◽  
Vol 251 (2) ◽  
pp. R289-R294 ◽  
Author(s):  
J. P. Koepke ◽  
S. Jones ◽  
G. F. DiBona

The effects of a stressful environmental stimulus (air stress) on mean arterial pressure, heart rate, renal sympathetic nerve activity, and renal function were studied in conscious deoxycorticosterone acetate-sodium chloride (DOCA-NaCl) hypertensive rats, sham DOCA-NaCl normotensive rats, and DOCA-NaCl rats with renal denervation. In conscious DOCA-NaCl hypertensive rats, air stress decreased urine flow rate [36% from 17.9 +/- 3.0 microliter X min-1 X 100 g body wt-1 (BW)], urinary sodium excretion (39% from 3.1 +/- 0.5 microeq X min-1 X 100 g BW-1), fractional water excretion (24% from 4.72 +/- 1.00%), and fractional sodium excretion (28% from 5.72 +/- 1.08%) and increased renal sympathetic nerve activity (94% from 8.3 +/- 0.6 integrator resets/min), but no changes occurred in glomerular filtration rate (-15% from 0.40 +/- 0.06 ml X min-1 X 100 g BW-1) or effective renal plasma flow (-7% from 2.50 +/- 0.53 ml X min-1 X 100 g BW-1). Air stress had no effect on these measures in conscious sham DOCA-NaCl normotensive rats or DOCA-NaCl rats with renal denervation. Mean arterial pressure and heart rate were unaffected by air stress in these three groups. Renal denervation lowered base-line mean arterial pressure in DOCA-NaCl rats. Thus DOCA-NaCl hypertensive rats respond to environmental stress with increased renal sympathetic nerve activity and, consequently, antidiuresis and antinatriuresis.


2008 ◽  
Vol 283 (36) ◽  
pp. 24554-24560 ◽  
Author(s):  
Manabu Murakami ◽  
Takayoshi Ohba ◽  
Feng Xu ◽  
Eisaku Satoh ◽  
Ichiro Miyoshi ◽  
...  

1986 ◽  
Vol 40 (2) ◽  
pp. 112-119 ◽  
Author(s):  
E. van Rhede van der Kloot ◽  
J. Drukker ◽  
H.A.J. Lemmens ◽  
J.M. Greep

2021 ◽  
Vol 42 (5) ◽  
pp. 1001-1008
Author(s):  
Kyeong-seok Wang ◽  
In-cheol Chae ◽  
Mi-so Park ◽  
Su-a Son ◽  
Seong-il Park ◽  
...  

Objective: The aim of this case study was to describe a case of iris diagnosis of primary hyperhidrosis and the use of Korean medicine.Methods: A patient with symptoms of hyperhidrosis was diagnosed as having Taeeumin after assessment using the four basic Korean diagnostic methods. Iris diagnosis was used for further examination. The images obtained showed a remarkably defined collarette and increased nerve rings, which suggested an overactive sympathetic nerve system. Under the diagnosis of Taeeum, a Korean herbal medicine was prescribed with additional herbs to help alleviate the hyperactivity of the sympathetic nervous system.Results: The patient had been receiving treatment for hyperhidrosis for >30 years, with various medical attempts to relieve her symptoms, which were ineffective. She showed signs of improvement from day 4 into the treatment, and 80% of her symptoms were improved after completing a 6-week treatment course.Conclusion: The herbal medicine prescribed to the patient proved effective for reducing her chronic symptoms that had been unresponsive to previous medical treatments.


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