scholarly journals The role of hypothalamo-sympathetic nerve system to maintain high blood pressure in DOCA hypertensive rats.

1980 ◽  
Vol 44 (5) ◽  
pp. 409-410 ◽  
Author(s):  
KAZUO TAKEDA ◽  
SUSUMU SASAKI ◽  
ISAO KAIMASU ◽  
MINABU YOSHIMURA ◽  
MASAO NAKAGAWA ◽  
...  
Keyword(s):  
Blood Pressure ◽  
High Blood Pressure ◽  
Sympathetic Nerve ◽  
Hypertensive Rats ◽  
Sympathetic Nerve System ◽  
Nerve System

scholarly journals Renal denervation inhibits hypothalamo-sympathetic nerve system in normotensive and hypertensive rats.

1985 ◽  
Vol 49 (9) ◽  
pp. 997-1004 ◽  
Author(s):  
KAZUO TAKEDA ◽  
HIROSHI OKAJIMA ◽  
MASAHIRO YOSHIGA ◽  
LI-CHIK LEE ◽  
ISAO IYODA ◽  
...  
Keyword(s):  
Sympathetic Nerve ◽  
Renal Denervation ◽  
Hypertensive Rats ◽  
Sympathetic Nerve System ◽  
Nerve System

Increased Pressor Responsiveness to Enkephalin in Spontaneously Hypertensive Rats: The Role of Vasopressin

1980 ◽  
Vol 59 (s6) ◽  
pp. 235s-237s ◽  
Author(s):  
R. W. Rockhold ◽  
J. T. Crofton ◽  
L. Share
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Pressor Response ◽  
Cardiovascular Effects ◽  
Hypertensive Rats ◽  
Methionine Enkephalin ◽  
Spontaneously Hypertensive ◽  
Wistar Kyoto Rats ◽  
Wistar Kyoto

1. The cardiovascular effects of an enkephalin analogue were examined in spontaneously hypertensive and normotensive Wistar-Kyoto rats. (D-Ala2)-methionine enkephalin caused a biphasic increase in blood pressure and an increase in heart rate after intracerebroventricular injection. 2. The initial pressor response to (D-Ala2)-methionine enkephalin was greater in hypertensive than in normotensive rats. No difference was noted between groups during the secondary pressor response. Heart rate increases paralleled the secondary increase in blood pressure. 3. Naloxone pretreatment abolished the secondary increase in blood pressure and the tachycardia, but did not blunt the initial pressor response in female Wistar-Kyoto rats. 4. Plasma levels of arginine vasopressin were depressed during the plateau phase of the pressor response in hypertensive rats given intracerebroventricular (d-Ala2)-methionine enkephalin. 5. The results suggest that the cardiovascular effects of central enkephalin are not due to vasopressin, but may involve activation of the sympathetic nervous system.

Sign in / Sign up

Export Citation Format

Share Document